Risk for colorectal cancer in elderly persons and possible methodologies for their screening

European Journal of Gastroenterology and Hepatology

Volumn 23, Issue 5, 2011, Pages 431-437

  Rozen, Paul ^a,b   Shabtai, Ester I ^a   Liphshitz, Irena ^c   Barchana, Micha ^c,d  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c MINISTRY OF HEALTH   (Israel)

^d UNIVERSITY OF HAIFA   (Israel)

Author keywords

Cancer site; colonoscopy; colorectal cancer; elderly persons; epidemiology; Jews; occult blood; screening; sex

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER REGISTRY; CANCER RISK; CANCER SCREENING; COLON POLYPOSIS; COLONOSCOPY; COLORECTAL CANCER; FEMALE; HUMAN; IMMUNOCHEMICAL FECAL OCCULT BLOOD TEST; MAJOR CLINICAL STUDY; MALE; OCCULT BLOOD TEST; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ADENOMATOUS POLYPS; AGED; COLORECTAL NEOPLASMS; EARLY DETECTION OF CANCER; FEMALE; HUMANS; MALE; MASS SCREENING; OCCULT BLOOD; REGISTRIES; RETROSPECTIVE STUDIES; RISK; SENSITIVITY AND SPECIFICITY; SIGMOIDOSCOPY;

EID: 79955068291     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328345bc38     Document Type: Article

References (54)

1. Zavoral M, Suchanek S, Zavada F, Dusek L, Muzik J, Seifert B, et al. Colorectal cancer screening in Europe. World J Gastroenterol 2009; 15:5907-5915.
2. US Preventive Services Task Force Recommendation Statement. Screening for colorectal cancer. Ann Intern Med 2008; 149:627-637.
3. Zauber AG, Lansdorp-Vogelaar I, Knudsen AB,Wilschut J, Van Ballegooijen M, Kuntz KM. Evaluating test strategies for colorectal cancer screening: a decision analysis for the US Preventive Services Task Force. Ann Intern Med 2008; 149:659-669.
4. Israel Ministry of Health. Available at: http://www.health.gov.il/ (in Hebrew) (accessed 1 January 2011).
5. Cucino C, Buchner AM, Sonnenberg A. Continued rightward shift of colorectal cancer. Dis Colon Rectum 2002; 45:1035-1040.
6. Rabeneck L, Davila JA, El-Serag HB. Is there a true shift to the right colon in the incidence of colorectal cancer? Am J Gastroenterol 2003; 98:1400-1409. (Pubitemid 36741541)
7. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics. CA Cancer J Clin 2005; 55:74-108.
8. Meza R, Jeon J, Renehan AG, Luebeck EG. Colorectal cancer incidence trends in the United States and United Kingdom: evidence of right- to leftsided biological gradients with implications for screening. Cancer Res 2010; 70:5419-5429.
9. Shellnut JK,Wasvary HJ, Grodsky MB, Boura JA, Priest SG. Evaluating the age distribution of patients with colorectal cancer: are the United States Preventative Services Task Force guidelines for colorectal cancer screening appropriate? Dis Colon Rectum 2010; 53:5-8.
10. Rozen P, Liphshitz I, Barchana M. The changing epidemiology of colorectal cancer and its relevance for adapting screening guidelines and methods. Eur J Cancer Prev 2011; 20:46-53.
11. Rozen P, Levi Z, Hazazi R, Waked A, Vilkin A, Maoz E, et al. Quantitative colonoscopic evaluation of relative efficiencies of an immunochemical faecal occult blood test and a sensitive guaiac test for detecting significant colorectal neoplasms. Aliment Pharmacol Ther 2009; 29:450-457.
12. Hol L, Wilschut JA, Van Ballegooijen M, Van Vuuren AJ, Van der Valk H, Reijerink JC, et al. Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels. Br J Cancer 2009; 100:1103-1110.
13. Van Rossum LGM, Van Rijn AF, Verbeek ALM, Van Oijen MGH, Laheij RJF, Fockens P, et al. Colorectal cancer screening comparing no screening, immunochemical and guaiac fecal occult blood tests: a cost-effectiveness analysis. Int J Cancer 2010. doi: 10.1002/ijc.25530. (in press).
14. Imperiale TF,Wagner DR, Lin CY, Larkin GN, Rogge JD, Ransohoff DF. Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings. N Engl J Med 2000; 343:169-174. (Pubitemid 30489213)
15. Leiberman DA, Holub J, Eisen G, Kraemer D, Morris CD. Utilization of colonoscopy in the United States: results from a national consortium. Gastrointest Endosc 2005; 62:875-883. (Pubitemid 41654422)
16. Gupta AK, Melton LJ III, Petersen GM, Timmons LJ, Vege SS, Harmsen WS, et al. Changing trends in the incidence, stage, survival, and screen-detection of colorectal cancer: a population-based study. Clin Gastroenterol Hepatol 2005; 3:150-158. (Pubitemid 40220310)
17. Schoenfeld P, Cash B, Flood A, Dobhan R, Eastone J, Coyle W, et al. Colonoscopic screening of average-risk women for colorectal neoplasia. N Engl J Med 2005; 352:2061-2068. (Pubitemid 40664307)
18. Rozen P Comaneshter D Levi Z Hazazi R, Vilkin A, Maoz E, et al. Cumulative evaluation of a quantitative immunochemical fecal occult blood test to determine its optimal clinical use. Cancer 2010; 116:2115-2125.
19. Hazazi R, Rozen P, Leshno M, Levi Z, Samuel Z,Waked A, et al. Can patients at high risk for significant colorectal neoplasms and having normal quantitative faecal occult blood test postpone elective colonoscopy? Aliment Pharmacol Ther 2010; 31:523-533.
20. Guittet L, Launoy G. Screening for colorectal cancer (letter). N Engl J Med 2010; 362:84-85.
21. Lane JM, Chow E, Young GP, Good N, Smith A, Bull J, et al. Interval fecal immunochemical testing in a colonoscopic surveillance program speeds detection of colorectal neoplasia. Gastroenterology 2010; 139:1918-1926.
22. Levi Z, Birkenfeld S, Vilkin A, Bar-Chana M, Lifshitz I, Chared M, et al. A higher detection rate for colorectal cancer and advanced adenomatous polyp for screening with immunochemical fecal occult blood test than guaiac fecal occult blood test, despite lower compliance rate. A prospective, controlled, feasibility study. Int J Cancer 2010 (in press).
23. Israel National Cancer Registry. Available at: www.health.gov.il/icr (accessed 1 January 2011).
24. SEER Program. Self-instructional manual for cancer registrars. 3rd ed. USA: National Institutes of Health, National Cancer Institute; 1999.
25. Statistical Abstract of Israel 2009. Central Bureau of Statistics publication. Government Press, Jerusalem. Available at: (accessed 1 January 2011).
26. Ko CW, Sonnenberg A. Comparing risks and benefits of colorectal cancer screening in elderly patients. Gastroenterology 2005; 129:1163-1170. (Pubitemid 41446856)
27. Australia - The National Bowel Cancer Screening Program. Available at: www.cancerscreening.gov.au. (accessed 2010).
28. Regula J, Rupinski M, Kraszewska E, Polkowski M, Pachlewski J, Orlowska J, et al. Colonoscopy in colorectal-cancer screening for detection of advanced neoplasia. N Engl J Med 2006; 355:1863-1872. (Pubitemid 44664644)
29. Zorzi M, Fedato C, Naldoni C, Sassatelli R, Sassoli De Bianchi P, Senore C, et al. Screening for colorectal cancer in Italy: 2007 survey. Epidemiol Prev 2009; 33 (Suppl 2):57-74.
30. Goulard H, Boussac-Zarebska M, Ancelle-Park R, Bloch J. French colorectal cancer screening pilot programme: results of the first round. J Med Screen 2008; 15:143-148.
31. Scottish Bowel Screening. Available at: http:// www.bowelscreening.scot. nhs.uk/ (accessed 1 January 2011).
32. Schub R, Steinheber FU. Rightward shift of colon cancer: a feature of the aging gut. J Clin Gastroenterol 1986; 8:630-634. (Pubitemid 17207507)
33. Jass JR. Subsite distribution and incidence of colorectal cancer in New Zealand, 1974-1983. Dis Colon Rectum 1991; 34:56-59.
34. Okamoto M, Shiratori Y, Yamaji Y, Kato J, Ikenoue T, Togo G, et al. Relationship between age and site of colorectal cancer based on colonoscopy findings. Gastrointest Endosc 2002; 55:548-551. (Pubitemid 41123509)
35. Lieberman D. Colon cancer screening and surveillance controversies. Review. Curr Opin Gastroenterol 2009; 25:422-427.
36. Etzioni DA, Beart RWJr, Madoff RD, Ault GT. Impact of the aging population on the demand for colorectal procedures. Dis Colon Rectum 2009; 52:583-590.
37. Albert RH, Clark MM. Cancer screening in the older patient. Am Fam Physician 2008; 78:1369-1374.
38. Walter LC, Covinsky KE. Cancer screening in elderly patients: a framework for individualized decision making. JAMA 2001; 285:2750-2756. (Pubitemid 32525372)
39. Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D, Tinetti ME. The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Ann Intern Med 2006; 145:646-653. (Pubitemid 46768839)
40. Maheshwari S, Patel T, Patel P. Screening for colorectal cancer in elderly persons: who should we screen and when can we stop? J Aging Health 2008; 20:126-139.
41. Braithwaite RS, Fiellin D, Justice AC. The payoff time: a flexible framework to help clinicians decide when patients with comorbid disease are not likely to benefit from practice guidelines. Med Care 2009; 47:610-617.
42. Pabby A, Suneja A, Heeren T, Farraye FA. Flexible sigmoidoscopy for colorectal cancer screening in the elderly. Dig Dis Sci 2005; 50:2147-2152. (Pubitemid 41504104)
43. Stevens T, Burke CA. Colonoscopy screening in the elderly: when to stop? Am J Gastroenterol 2003; 98:1881-1885. (Pubitemid 36959174)
44. Duncan JE, Sweeney WB, Trudel JL, Madoff RD, Mellgren AF. Colonoscopy in the elderly: low risk, low yield in asymptomatic patients. Dis Colon Rectum 2006; 49:646-551.
45. Lin OS, Kozarek RA, Schembre DB, Ayub K, Gluck M, Drennan F, et al. Screening colonoscopy in very elderly patients: prevalence of neoplasia and estimated impact on life expectancy. JAMA 2006; 295:2357-2365. (Pubitemid 43788103)
46. Schoen RE. Debate: should screening colonoscopy be performed on an 88-yr-old healthy patient? Am J Gastroenterol 2006; 101:1713-1715; discussion 1717-1718.
47. Strul H, Kariv R, Leshno M, Halak A, Jakubowicz M, Santo M, et al. The prevalence rate and anatomic location of colorectal adenoma and cancer detected by colonoscopy in average-risk individuals aged 40-80 years. Am J Gastroenterol 2006; 101:255-262. (Pubitemid 43381664)
48. Kahi CJ, Azzouz F, Juliar BE, Imperiale TF. Survival of elderly persons undergoing colonoscopy: implications for colorectal cancer screening and surveillance. Gastrointest Endosc 2007; 66:544-550. (Pubitemid 47304413)
49. Okamoto M, Kawabe T, Yamaji Y, Kato J, Ikenoue T, Togo G, et al. Flat-type early colorectal cancer preferentially develops in right-sided colon in older patients. Dis Colon Rectum 2005; 48:101-107. (Pubitemid 40895661)
50. Hosokawa O, Shirasaki S, Kaizaki Y, Hayashi H, Douden K, Hattori M. Invasive colorectal cancer detected up to 3 years after a colonoscopy negative for cancer. Endoscopy 2003; 35:506-510. (Pubitemid 36705642)
51. Bressler B, Paszat LF, Vinden C, Li C, He J, Rabeneck L. Colonoscopic miss rates for right-sided colon cancer: a population-based analysis. Gastroenterology 2004; 127:452-456. (Pubitemid 39091893)
52. Pabby A, Schoen RE, Weissfeld JL, Burt R, Kikendall JW, Lance P, et al. Analysis of colorectal cancer occurrence during surveillance colonoscopy in the dietary Polyp Prevention Trial. Gastrointest Endosc 2005; 61:385-391. (Pubitemid 40349030)
53. Stock C, Brenner H. Utilization of lower gastrointestinal endoscopy and fecal occult blood test in 11 European countries: evidence from the survey of health, aging and retirement in Europe (share). Endoscopy 2010; 42:546-556.
54. Duffy MJ, Van Rossum LG, Van Turenhout ST, Malminiemi O, Sturgeon C, Lamerz R, et al. Use of Faecal markers in screening for colorectal neoplasia: a european group on tumor markers position paper. Int J Cancer 2011; 128:3-11.