Development of an immunoaffinity column for the determination of T-2 and HT-2 toxins in cereals using liquid chromatography with fluorescence detection

ACS Symposium Series

Volumn 1001, Issue , 2008, Pages 276-284

  Donnelly, C ^a   Pollock, A ^a   Heidtmann, Y ^a   Marley, E ^a  

^a R Biopharm Rhone Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; LAWS AND LEGISLATION; LIQUID CHROMATOGRAPHY; METABOLITES; SODIUM CHLORIDE; TOXIC MATERIALS; WATER FILTRATION;

ANALYTICAL METHOD; EUROPEAN UNION; FLUORESCENCE DETECTION; IMMUNOAFFINITY COLUMNS; LIMIT OF DETECTION; PERFORMANCE CRITERION; RESEARCH CENTRES; SWITZERLAND;

ANTIGEN-ANTIBODY REACTIONS;

EID: 79955056385     PISSN: 00976156     EISSN: 19475918     Source Type: Book Series    
DOI: 10.1021/bk-2008-1001.ch015     Document Type: Conference Paper

References (9)

1. European Commission Regulation (E No 856/2005 amending Regulation (E No 466/2001 as regards Fusarium toxins.
2. Josephs, R.D.; Derbyshire, M.; Stroka, J.; Emons, H.; Anklam E. Trichothecenes: reference materials and method validation. Toxicol. Lett. 2004, 153, 123-132.
3. Langseth, W.; Rundberget, T. Instrumental methods for determination of non-macrocyclic trichothecenes in cereals, foodstuffs and cultures. J. Chromatogr. A 1998, 815, 103-121.
4. Council for Agricultural Science and Technology (CAST). Mycotoxins, Risks in Plant, Animal and Human Systems, Task Force Report No. 139, CAST: Ames, IA, January 2003.
5. Berger, U.; Oehme, M.; Kuhn, F. Quantitative determination and structure elucidation of type A and B trichothecenes by HPLC/ion trap multiple mass spectrometry. J. Agric. Food Chem. 1999, 47, 4240-4245.
6. Krska, R.; Baumgartner, S.; Josephs, R. The state-of-The-Art in the analysis of type-A and -B trichothecene mycotoxins in cereals. Fresenius J. Anal. Chem. 2001, 37, 285-299.
7. Tanaka, T.; Yoneda, A.; Inoue, S.; Sugiura, Y.; Ueno, Y. Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography-mass spectrometry J. Chromatogr. A 2000, 882, 23-28.
8. Klotzel, M.; Lauber, W.; Humpf, H. U. A new solid phase extraction cleanup method for the determination of 12 type A and type B trichothecenes in cereals and cereal-based food by LC-MS/MS. Mol. Nutr.Food Res. 2006, 50, 261-269.
9. Pascale, M.; Haidukowski, M.; Visconti, A. Determination of T-2 toxin in cereal grains by liquid chromatography with fluorescence detection after immunoaffinity column clean-up and derivatization with 1-Anthroylnitrile. J. Chromatogr. A 2003, 989, 257-264