Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway

Virology Journal

Volumn 8, Issue , 2011, Pages

  Zaremba, Angelika ^a   Schmuecker, Ursula ^b   Esche, Helmut ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRAL E1A ONCOPROTEIN; HUMAN PAPILLOMAVIRUS TYPE 16 E7 ONCOPROTEIN; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SPROUTY PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; E1A PROTEIN; MEMBRANE PROTEIN; PHOSPHOPROTEIN; SPRY1 PROTEIN, HUMAN; SPRY1 PROTEIN, MOUSE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOPLASM; DELETION MUTANT; FEMALE; GENE REGULATORY NETWORK; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSACTIVATION; VIRUS REPLICATION; ADENOVIRUS; ANIMAL; CELL LINE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENE DELETION; METABOLISM; PATHOGENICITY; PROTEIN ANALYSIS; TWO HYBRID SYSTEM;

ADENOVIRIDAE; ADENOVIRUS E1A PROTEINS; ANIMALS; CELL LINE; CYTOPLASM; MEMBRANE PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; PHOSPHOPROTEINS; PROTEIN INTERACTION MAPPING; PROTEIN-TYROSINE KINASES; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 79955042545     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-192     Document Type: Article

References (50)

1. Adenovirus promoters and E1A transactivation. AJ Berk, Annu Rev Genet 1986 20 45 79 10.1146/annurev.ge.20.120186.000401 3028247
2. Regulation of viral and cellular gene expression by E1A proteins encoded by the oncogenic adenovirus type 12. D Brockmann H Esche, Curr Top Microbiol Immunol 1995 199 Pt 3 81 112 7555085
3. Adenovirus E1A: remodelling the host cell, a life or death experience. PH Gallimore AS Turnell, Oncogene 2001 20 7824 7835 10.1038/sj.onc.1204913 11753665 (Pubitemid 33135309)
4. Regulation of p53-dependent apoptosis by E1A and E1B. E White, Curr Top Microbiol Immunol 1995 199 Pt 3 34 58 7555083
5. E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. S Wienzek J Roth M Dobbelstein, J Virol 2000 74 193 202 10.1128/JVI.74.1.193-202.2000 10590106 (Pubitemid 30002898)
6. Assessing the role of E1A in the differential oncogenicity of group A and group C human adenoviruses. J Williams M Williams C Liu G Telling, Curr Top Microbiol Immunol 1995 199 Pt 3 149 175 7555075
7. Mapping of adenovirus 12 mRNA's transcribed from the transforming region. Y Sawada K Fujinaga, J Virol 1980 36 639 651 7463554 (Pubitemid 11194303)
8. A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Z Arany D Newsome E Oldread DM Livingston R Eckner, Nature 1995 374 81 84 10.1038/374081a0 7870178
9. E1A 13S and 12S mRNA products made in Escherichia coli both function as nucleus-localized transcription activators but do not directly bind DNA. B Ferguson B Krippl O Andrisani N Jones H Westphal M Rosenberg, Mol Cell Biol 1985 5 2653 2661 2942760 (Pubitemid 15249551)
10. The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Y Li C Graham S Lacy AM Duncan P Whyte, Genes Dev 1993 7 2366 2377 10.1101/gad.7.12a.2366 8253383 (Pubitemid 24003240)
11. Roles for the coactivators CBP and p300 and the APC/C E3 ubiquitin ligase in E1A-dependent cell transformation. AS Turnell JS Mymryk, Br J Cancer 2006 95 555 560 10.1038/sj.bjc.6603304 16880778 (Pubitemid 44325894)
12. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. P Whyte KJ Buchkovich JM Horowitz SH Friend M Raybuck RA Weinberg E Harlow, Nature 1988 334 124 129 10.1038/334124a0 2968522
13. Acetylation of the adenovirus-transforming protein E1A determines nuclear localization by disrupting association with importin-alpha. DL Madison P Yaciuk RP Kwok JR Lundblad, J Biol Chem 2002 277 38755 38763 10.1074/jbc.M207512200 12161448 (Pubitemid 35154738)
14. Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity. P Fax CR Carlson P Collas K Tasken H Esche D Brockmann, Virology 2001 285 30 41 10.1006/viro.2001.0926 11414803 (Pubitemid 32589005)
15. RACK1 interacts with E1A and rescues E1A-induced yeast growth inhibition and mammalian cell apoptosis. N Sang A Severino P Russo A Baldi A Giordano AM Mileo MG Paggi A De Luca, J Biol Chem 2001 276 27026 27033 10.1074/jbc. M010346200 11358958
16. RACK1 is a functional target of the E1A oncoprotein. A Severino A Baldi G Cottone M Han N Sang A Giordano AM Mileo MG Paggi A De Luca, J Cell Physiol 2004 199 134 139 10.1002/jcp.10448 14978742 (Pubitemid 38197521)
17. Regulation of the 26S proteasome by adenovirus E1A. AS Turnell RJ Grand C Gorbea X Zhang W Wang JS Mymryk PH Gallimore, Embo J 2000 19 4759 4773 10.1093/emboj/19.17.4759 10970867
18. Sprouty, an intracellular inhibitor of Ras signaling. T Casci J Vinos M Freeman, Cell 1999 96 655 665 10.1016/S0092-8674(00)80576-0 10089881 (Pubitemid 29122808)
19. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. N Hacohen S Kramer D Sutherland Y Hiromi MA Krasnow, Cell 1998 92 253 263 10.1016/S0092-8674(00)80919-8 9458049 (Pubitemid 28073048)
20. Modulation of signalling by Sprouty: a developing story. HJ Kim D Bar-Sagi, Nat Rev Mol Cell Biol 2004 5 441 450 10.1038/nrm1400 15173823 (Pubitemid 38745494)
21. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. G Minowada LA Jarvis CL Chi A Neubuser X Sun N Hacohen MA Krasnow GR Martin, Development 1999 126 4465 4475 10498682
22. Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. MA Impagnatiello S Weitzer G Gannon A Compagni M Cotten G Christofori, J Cell Biol 2001 152 1087 1098 10.1083/jcb.152.5.1087 11238463 (Pubitemid 34286083)
23. Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation. I Gross B Bassit M Benezra JD Licht, J Biol Chem 2001 276 46460 46468 10.1074/jbc.M108234200 11585837
24. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. D Chambers I Mason, Mech Dev 2000 91 361 364 10.1016/S0925-4773(99)00288-9 10704865 (Pubitemid 30125939)
25. Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. OD Klein G Minowada R Peterkova A Kangas BD Yu H Lesot M Peterka J Jernvall GR Martin, Dev Cell 2006 11 181 190 10.1016/j.devcel.2006.05.014 16890158 (Pubitemid 44159239)
26. Sprouty: how does the branch manager work? GR Guy ES Wong P Yusoff S Chandramouli TL Lo J Lim CW Fong, J Cell Sci 2003 116 3061 3068 10.1242/jcs.00652 12829736 (Pubitemid 37038955)
27. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. JD Tefft M Lee S Smith M Leinwand J Zhao P Bringas Jr DL Crowe D Warburton, Curr Biol 1999 9 219 222 10.1016/S0960-9822(99)80094-3 10074434 (Pubitemid 29120388)
28. Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. H Hanafusa S Torii T Yasunaga E Nishida, Nat Cell Biol 2002 4 850 858 10.1038/ncb867 12402043 (Pubitemid 35331359)
29. The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes. J Lim P Yusoff ES Wong S Chandramouli DH Lao CW Fong GR Guy, Mol Cell Biol 2002 22 7953 7966 10.1128/MCB.22.22.7953-7966.2002 12391162 (Pubitemid 35217304)
30. Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function. CW Fong HF Leong ES Wong J Lim P Yusoff GR Guy, J Biol Chem 2003 278 33456 33464 10.1074/jbc.M301317200 12815057 (Pubitemid 37055800)
31. Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop. JM Mason DJ Morrison B Bassit M Dimri H Band JD Licht I Gross, Mol Biol Cell 2004 15 2176 2188 10.1091/mbc.E03-07-0503 15004239 (Pubitemid 38580637)
32. Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty. H Hanafusa S Torii T Yasunaga K Matsumoto E Nishida, J Biol Chem 2004 279 22992 22995 10.1074/jbc.M312498200 15031289 (Pubitemid 38685601)
33. mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins. D Tefft M Lee S Smith DL Crowe S Bellusci D Warburton, Am J Physiol Lung Cell Mol Physiol 2002 283 700 706 12225946
34. The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer. TL Lo P Yusoff CW Fong K Guo BJ McCaw WA Phillips H Yang ES Wong HF Leong Q Zeng,, et al. Cancer Res 2004 64 6127 6136 10.1158/0008-5472.CAN-04-1207 15342396 (Pubitemid 39129413)
35. The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer. B Kwabi-Addo J Wang H Erdem A Vaid P Castro G Ayala M Ittmann, Cancer Res 2004 64 4728 4735 10.1158/0008-5472.CAN-03-3759 15256439 (Pubitemid 38924514)
36. Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines. S Bloethner B Chen K Hemminki J Muller-Berghaus S Ugurel D Schadendorf R Kumar, Carcinogenesis 2005 26 1224 1232 15760917 (Pubitemid 41417899)
37. Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms. H Sutterluty CE Mayer U Setinek J Attems S Ovtcharov M Mikula W Mikulits M Micksche W Berger, Mol Cancer Res 2007 5 509 520 10.1158/1541-7786.MCR-06-0273 17510316 (Pubitemid 46903958)
38. Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma. CW Fong MS Chua AB McKie SH Ling V Mason R Li P Yusoff TL Lo HY Leung SK So GR Guy, Cancer Res 2006 66 2048 2058 10.1158/0008-5472.CAN-05-1072 16489004
39. Distinct requirements for the Sprouty domain for functional activity of Spred proteins. JA King AF Straffon GM D'Abaco CL Poon ST I CM Smith M Buchert NM Corcoran NE Hall BA Callus,, et al. Biochem J 2005 388 445 454 10.1042/BJ20041284 15683364 (Pubitemid 40839921)
40. Spred is a Sprouty-related suppressor of Ras signalling. T Wakioka A Sasaki R Kato T Shouda A Matsumoto K Miyoshi M Tsuneoka S Komiya R Baron A Yoshimura, Nature 2001 412 647 651 10.1038/35088082 11493923 (Pubitemid 32772277)
41. Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. S Chellappan VB Kraus B Kroger K Munger PM Howley WC Phelps JR Nevins, Proc Natl Acad Sci USA 1992 89 4549 4553 10.1073/pnas.89.10.4549 1316611
42. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. N Dyson P Guida K Munger E Harlow, J Virol 1992 66 6893 6902 1331501
43. Positive regulation of jun/AP-1 by E1A. R de Groot N Foulkes M Mulder W Kruijer P Sassone-Corsi, Mol Cell Biol 1991 11 192 201 1824713 (Pubitemid 21895196)
44. E1A dependent up-regulation of c-jun/AP-1 activity. I Kitabayashi R Chiu G Gachelin K Yokoyama, Nucleic Acids Res 1991 19 649 655 10.1093/nar/19.3.649 1826351 (Pubitemid 21897054)
45. Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways. C Rubin Y Zwang N Vaisman D Ron Y Yarden, J Biol Chem 2005 280 9735 9744 15637081 (Pubitemid 40409672)
46. Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. AJ Berk, Oncogene 2005 24 7673 7685 10.1038/sj.onc.1209040 16299528 (Pubitemid 41670670)
47. Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase. Y Tsumura J Toshima OC Leeksma K Ohashi K Mizuno, Biochem J 2005 387 627 637 10.1042/BJ20041181 15584898 (Pubitemid 40685696)
48. Intermolecular interactions of Sprouty proteins and their implications in development and disease. F Edwin K Anderson C Ying TB Patel, Mol Pharmacol 2009 76 679 691 10.1124/mol.109.055848 19570949
49. hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl. AB Hall N Jura J DaSilva YJ Jang D Gong D Bar-Sagi, Curr Biol 2003 13 308 314 10.1016/S0960-9822(03)00086-1 12593796 (Pubitemid 36230021)
50. A novel role of Sprouty 2 in regulating cellular apoptosis. F Edwin TB Patel, J Biol Chem 2008 283 3181 3190 18070883