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Volumn 39, Issue 5, 2011, Pages 882-890

Liver-selective expression of human arylamine N-acetyltransferase NAT2 in transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

4 BIPHENYLAMINE; AMINOSALICYLIC ACID; ARYLAMINE ACETYLTRANSFERASE; ARYLAMINE N ACETYLTRANSFERASE 2; SULFADIMIDINE; UNCLASSIFIED DRUG;

EID: 79955036094     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.038216     Document Type: Article
Times cited : (14)

References (46)
  • 1
    • 70350344950 scopus 로고    scopus 로고
    • Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenylinduced DNA adducts and mutations
    • Bendaly J, Doll MA, Millner LM, Metry KJ, Smith NB, Pierce WM Jr, and Hein DW (2009) Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenylinduced DNA adducts and mutations. Mutat Res 671:13-19.
    • (2009) Mutat Res , vol.671 , pp. 13-19
    • Bendaly, J.1    Doll, M.A.2    Millner, L.M.3    Metry, K.J.4    Smith, N.B.5    Pierce Jr., W.M.6    Hein, D.W.7
  • 2
    • 23644432643 scopus 로고    scopus 로고
    • Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice
    • DOI 10.1038/sj.tpj.6500319
    • Cao W, Chau B, Hunter R, Strnatka D, McQueen CA, and Erickson RP (2005) Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice. Pharmacogenomics J 5:255-261. (Pubitemid 41131717)
    • (2005) Pharmacogenomics Journal , vol.5 , Issue.4 , pp. 255-261
    • Cao, W.1    Chau, B.2    Hunter, R.3    Strnatka, D.4    McQueen, C.A.5    Erickson, R.P.6
  • 5
    • 54349128898 scopus 로고    scopus 로고
    • Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment
    • Cheung C and Gonzalez FJ (2008) Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment. J Pharmacol Exp Ther 327: 288-299.
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 288-299
    • Cheung, C.1    Gonzalez, F.J.2
  • 7
    • 1542320024 scopus 로고    scopus 로고
    • Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: A cellular and mechanistic study
    • DOI 10.1074/jbc.M311469200
    • Dairou J, Atmane N, Rodrigues-Lima F, and Dupret JM (2004) Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: A cellular and mechanistic study. J Biol Chem 279: 7708-7714. (Pubitemid 38294653)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.9 , pp. 7708-7714
    • Dairou, J.1    Atmane, N.2    Rodrigues-Lima, F.3    Dupret, J.-M.4
  • 9
    • 77954913118 scopus 로고    scopus 로고
    • Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes
    • Doll MA, Zang Y, Moeller T, and Hein DW (2010) Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes. J Pharmacol Exp Ther 334:540-544.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 540-544
    • Doll, M.A.1    Zang, Y.2    Moeller, T.3    Hein, D.W.4
  • 11
    • 0028278431 scopus 로고
    • 191 and NAT2(341/803)) and wild-type human polymorphic N- acetyltransferase (NAT2) alleles
    • Ferguson RJ, Doll MA, Rustan TD, Gray K, and Hein DW (1994) Cloning, expression, and functional characterization of two mutant (NAT2191 and NAT2341/803) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles. Drug Metab Dispos 22:371-376. (Pubitemid 24158534)
    • (1994) Drug Metabolism and Disposition , vol.22 , Issue.3 , pp. 371-376
    • Ferguson, R.J.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Hein, D.W.5
  • 13
    • 0020051095 scopus 로고
    • Genetic regulation of aromatic amine N-acetylation in inbred mice
    • Glowinski IB and Weber WW (1982) Genetic regulation of aromatic amine N-acetylation in inbred mice. J Biol Chem 257:1424-1430. (Pubitemid 12121652)
    • (1982) Journal of Biological Chemistry , vol.257 , Issue.3 , pp. 1424-1430
    • Glowinski, I.B.1    Weber, W.W.2
  • 14
    • 0025967717 scopus 로고
    • Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
    • Grant DM, Blum M, Beer M, and Meyer UA (1991) Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes. Mol Pharmacol 39:184-191.
    • (1991) Mol Pharmacol , vol.39 , pp. 184-191
    • Grant, D.M.1    Blum, M.2    Beer, M.3    Meyer, U.A.4
  • 15
    • 0037201542 scopus 로고    scopus 로고
    • Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
    • DOI 10.1016/S0027-5107(02)00153-7, PII S0027510702001537
    • Hein D (2002) Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis. Mutat Res 506-507:65-77. (Pubitemid 35286541)
    • (2002) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.506-507 , pp. 65-77
    • Hein, D.W.1
  • 16
    • 33645117090 scopus 로고    scopus 로고
    • N-Acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk
    • Hein DW (2006) N-Acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 25:1649-1658.
    • (2006) Oncogene , vol.25 , pp. 1649-1658
    • Hein, D.W.1
  • 17
    • 67649243788 scopus 로고    scopus 로고
    • N-Acetyltransferase SNPs: Emerging concepts serve as a paradigm for understanding complexities of personalized medicine
    • Hein DW (2009) N-Acetyltransferase SNPs: Emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opin Drug Metab Toxicol 5:353-366.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 353-366
    • Hein, D.W.1
  • 19
    • 34247323530 scopus 로고    scopus 로고
    • Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-Specific mRNA in human tissues
    • DOI 10.1124/dmd.106.014621
    • Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727. (Pubitemid 46641541)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.5 , pp. 721-727
    • Husain, A.1    Zhang, X.2    Doll, M.A.3    States, J.C.4    Barker, D.F.5    Hein, D.W.6
  • 21
    • 13844316753 scopus 로고    scopus 로고
    • Cytochrome P450 activation of arylamines and heterocyclic amines
    • DOI 10.1146/annurev.pharmtox.45.120403.100010
    • Kim D and Guengerich FP (2005) Cytochrome P450 activation of arylamines and heterocyclic amines. Annu Rev Pharmacol Toxicol 45:27-49. (Pubitemid 40261797)
    • (2005) Annual Review of Pharmacology and Toxicology , vol.45 , pp. 27-49
    • Kim, D.1    Guengerich, F.P.2
  • 24
    • 77956925425 scopus 로고    scopus 로고
    • Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues
    • Lakics V, Karran EH, and Boess FG (2010) Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues. Neuropharmacology 59:367-374.
    • (2010) Neuropharmacology , vol.59 , pp. 367-374
    • Lakics, V.1    Karran, E.H.2    Boess, F.G.3
  • 29
    • 33845267470 scopus 로고    scopus 로고
    • The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
    • DOI 10.1038/nrc2015, PII NRC2015
    • Nebert DW and Dalton TP (2006) The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat Rev Cancer 6:947-960. (Pubitemid 44862679)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.12 , pp. 947-960
    • Nebert, D.W.1    Dalton, T.P.2
  • 30
    • 33947311640 scopus 로고    scopus 로고
    • Aromatic amines in experimental cancer research: Tissue-specific effects, an old problem and new solutions
    • Neumann HG (2007) Aromatic amines in experimental cancer research: Tissue-specific effects, an old problem and new solutions. Crit Rev Toxicol 37:211-236.
    • (2007) Crit Rev Toxicol , vol.37 , pp. 211-236
    • Neumann, H.G.1
  • 32
    • 33847068206 scopus 로고    scopus 로고
    • Overview of PDEs and their regulation
    • Omori K and Kotera J (2007) Overview of PDEs and their regulation. Circ Res 100:309-327.
    • (2007) Circ Res , vol.100 , pp. 309-327
    • Omori, K.1    Kotera, J.2
  • 33
    • 0023339694 scopus 로고
    • An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
    • Pinkert CA, Ornitz DM, Brinster RL, and Palmiter RD (1987) An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev 1:268-276.
    • (1987) Genes Dev , vol.1 , pp. 268-276
    • Pinkert, C.A.1    Ornitz, D.M.2    Brinster, R.L.3    Palmiter, R.D.4
  • 36
    • 56349101750 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms
    • Sim E, Lack N, Wang CJ, Long H, Westwood I, Fullam E, and Kawamura A (2008) Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms. Toxicology 254:170-183.
    • (2008) Toxicology , vol.254 , pp. 170-183
    • Sim, E.1    Lack, N.2    Wang, C.J.3    Long, H.4    Westwood, I.5    Fullam, E.6    Kawamura, A.7
  • 39
    • 33748886474 scopus 로고    scopus 로고
    • In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice
    • DOI 10.1124/dmd.106.010819
    • Sugamori KS, Brenneman D, and Grant DM (2006) In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. Drug Metab Dispos 34:1697-1702. (Pubitemid 44427472)
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.10 , pp. 1697-1702
    • Sugamori, K.S.1    Brenneman, D.2    Grant, D.M.3
  • 41
    • 0037561531 scopus 로고    scopus 로고
    • Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
    • DOI 10.1124/mol.64.1.170
    • Sugamori KS, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, and Grant DM (2003) Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double- knockout mice. Mol Pharmacol 64:170-179. (Pubitemid 36759829)
    • (2003) Molecular Pharmacology , vol.64 , Issue.1 , pp. 170-179
    • Sugamori, K.S.1    Wong, S.2    Gaedigk, A.3    Yu, V.4    Abramovici, H.5    Rozmahel, R.6    Grant, D.M.7
  • 44
    • 2142695286 scopus 로고    scopus 로고
    • Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation
    • DOI 10.1124/mol.65.5.1225
    • Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, and Nebert DW (2004) Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation. Mol Pharmacol 65:1225-1237. (Pubitemid 38543493)
    • (2004) Molecular Pharmacology , vol.65 , Issue.5 , pp. 1225-1237
    • Uno, S.1    Dalton, T.P.2    Derkenne, S.3    Curran, C.P.4    Miller, M.L.5    Shertzer, H.G.6    Nebert, D.W.7
  • 46


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.