-
1
-
-
70350344950
-
Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenylinduced DNA adducts and mutations
-
Bendaly J, Doll MA, Millner LM, Metry KJ, Smith NB, Pierce WM Jr, and Hein DW (2009) Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenylinduced DNA adducts and mutations. Mutat Res 671:13-19.
-
(2009)
Mutat Res
, vol.671
, pp. 13-19
-
-
Bendaly, J.1
Doll, M.A.2
Millner, L.M.3
Metry, K.J.4
Smith, N.B.5
Pierce Jr., W.M.6
Hein, D.W.7
-
2
-
-
23644432643
-
Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice
-
DOI 10.1038/sj.tpj.6500319
-
Cao W, Chau B, Hunter R, Strnatka D, McQueen CA, and Erickson RP (2005) Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice. Pharmacogenomics J 5:255-261. (Pubitemid 41131717)
-
(2005)
Pharmacogenomics Journal
, vol.5
, Issue.4
, pp. 255-261
-
-
Cao, W.1
Chau, B.2
Hunter, R.3
Strnatka, D.4
McQueen, C.A.5
Erickson, R.P.6
-
3
-
-
73549094922
-
N-Acetyltransferase 2 activity and folate levels
-
Cao W, Strnatka D, McQueen CA, Hunter RJ, and Erickson RP (2010) N-Acetyltransferase 2 activity and folate levels. Life Sci 86:103-106.
-
(2010)
Life Sci
, vol.86
, pp. 103-106
-
-
Cao, W.1
Strnatka, D.2
McQueen, C.A.3
Hunter, R.J.4
Erickson, R.P.5
-
5
-
-
54349128898
-
Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment
-
Cheung C and Gonzalez FJ (2008) Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment. J Pharmacol Exp Ther 327: 288-299.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 288-299
-
-
Cheung, C.1
Gonzalez, F.J.2
-
6
-
-
25444456926
-
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2
-
DOI 10.1021/tx050136g
-
Cheung C, Ma X, Krausz KW, Kimura S, Feigenbaum L, Dalton TP, Nebert DW, Idle JR, and Gonzalez FJ (2005) Differential metabolism of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2. Chem Res Toxicol 18:1471-1478. (Pubitemid 41361721)
-
(2005)
Chemical Research in Toxicology
, vol.18
, Issue.9
, pp. 1471-1478
-
-
Cheung, C.1
Ma, X.2
Krausz, K.W.3
Kimura, S.4
Feigenbaum, L.5
Dalton, T.P.6
Nebert, D.W.7
Idle, J.R.8
Gonzalez, F.J.9
-
7
-
-
1542320024
-
Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: A cellular and mechanistic study
-
DOI 10.1074/jbc.M311469200
-
Dairou J, Atmane N, Rodrigues-Lima F, and Dupret JM (2004) Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: A cellular and mechanistic study. J Biol Chem 279: 7708-7714. (Pubitemid 38294653)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 7708-7714
-
-
Dairou, J.1
Atmane, N.2
Rodrigues-Lima, F.3
Dupret, J.-M.4
-
8
-
-
63649098086
-
Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants
-
Dairou J, Petit E, Ragunathan N, Baeza-Squiban A, Marano F, Dupret JM, and Rodrigues-Lima F (2009) Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants. Toxicol Appl Pharmacol 236:366-371.
-
(2009)
Toxicol Appl Pharmacol
, vol.236
, pp. 366-371
-
-
Dairou, J.1
Petit, E.2
Ragunathan, N.3
Baeza-Squiban, A.4
Marano, F.5
Dupret, J.M.6
Rodrigues-Lima, F.7
-
9
-
-
77954913118
-
Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes
-
Doll MA, Zang Y, Moeller T, and Hein DW (2010) Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes. J Pharmacol Exp Ther 334:540-544.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 540-544
-
-
Doll, M.A.1
Zang, Y.2
Moeller, T.3
Hein, D.W.4
-
10
-
-
34250184674
-
Generation of 'humanized' hCYP1A1-1A2-Cyp1a1/1a2(-/-) mouse line
-
DOI 10.1016/j.bbrc.2007.05.202, PII S0006291X07011229
-
Dragin N, Uno S, Wang B, Dalton TP, and Nebert DW (2007) Generation of 'humanized' hCYP1A1-1A2-Cyp1a1/1a2(-/-) mouse line. Biochem Biophys Res Commun 359:635-642. (Pubitemid 46898998)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.359
, Issue.3
, pp. 635-642
-
-
Dragin, N.1
Uno, S.2
Wang, B.3
Dalton, T.P.4
Nebert, D.W.5
-
11
-
-
0028278431
-
191 and NAT2(341/803)) and wild-type human polymorphic N- acetyltransferase (NAT2) alleles
-
Ferguson RJ, Doll MA, Rustan TD, Gray K, and Hein DW (1994) Cloning, expression, and functional characterization of two mutant (NAT2191 and NAT2341/803) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles. Drug Metab Dispos 22:371-376. (Pubitemid 24158534)
-
(1994)
Drug Metabolism and Disposition
, vol.22
, Issue.3
, pp. 371-376
-
-
Ferguson, R.J.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Hein, D.W.5
-
12
-
-
0030734835
-
Neonatal mouse assay for tumorigenicity: Alternative to the chronic rodent bioassay
-
DOI 10.1006/rtph.1997.1125
-
Flammang TJ, Tungeln LS, Kadlubar FF, and Fu PP (1997) Neonatal mouse assay for tumorigenicity: Alternative to the chronic rodent bioassay. Regul Toxicol Pharmacol 26:230-240. (Pubitemid 27494297)
-
(1997)
Regulatory Toxicology and Pharmacology
, vol.26
, Issue.2
, pp. 230-240
-
-
Flammang, T.J.1
Von Tungeln, L.S.2
Kadlubar, F.F.3
Fu, P.P.4
-
13
-
-
0020051095
-
Genetic regulation of aromatic amine N-acetylation in inbred mice
-
Glowinski IB and Weber WW (1982) Genetic regulation of aromatic amine N-acetylation in inbred mice. J Biol Chem 257:1424-1430. (Pubitemid 12121652)
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.3
, pp. 1424-1430
-
-
Glowinski, I.B.1
Weber, W.W.2
-
14
-
-
0025967717
-
Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
-
Grant DM, Blum M, Beer M, and Meyer UA (1991) Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes. Mol Pharmacol 39:184-191.
-
(1991)
Mol Pharmacol
, vol.39
, pp. 184-191
-
-
Grant, D.M.1
Blum, M.2
Beer, M.3
Meyer, U.A.4
-
15
-
-
0037201542
-
Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
-
DOI 10.1016/S0027-5107(02)00153-7, PII S0027510702001537
-
Hein D (2002) Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis. Mutat Res 506-507:65-77. (Pubitemid 35286541)
-
(2002)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.506-507
, pp. 65-77
-
-
Hein, D.W.1
-
16
-
-
33645117090
-
N-Acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk
-
Hein DW (2006) N-Acetyltransferase 2 genetic polymorphism: Effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 25:1649-1658.
-
(2006)
Oncogene
, vol.25
, pp. 1649-1658
-
-
Hein, D.W.1
-
17
-
-
67649243788
-
N-Acetyltransferase SNPs: Emerging concepts serve as a paradigm for understanding complexities of personalized medicine
-
Hein DW (2009) N-Acetyltransferase SNPs: Emerging concepts serve as a paradigm for understanding complexities of personalized medicine. Expert Opin Drug Metab Toxicol 5:353-366.
-
(2009)
Expert Opin Drug Metab Toxicol
, vol.5
, pp. 353-366
-
-
Hein, D.W.1
-
18
-
-
0031969231
-
Expression of arylamine N-acetyltransferase in human intestine
-
Hickman D, Pope J, Patil SD, Fakis G, Smelt V, Stanley LA, Payton M, Unadkat JD, and Sim E (1998) Expression of arylamine N-acetyltransferase in human intestine. Gut 42:402-409. (Pubitemid 28197032)
-
(1998)
Gut
, vol.42
, Issue.3
, pp. 402-409
-
-
Hickman, D.1
Pope, J.2
Patil, S.D.3
Fakis, G.4
Smelt, V.5
Stanley, L.A.6
Payton, M.7
Unadkat, J.D.8
Sim, E.9
-
19
-
-
34247323530
-
Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-Specific mRNA in human tissues
-
DOI 10.1124/dmd.106.014621
-
Husain A, Zhang X, Doll MA, States JC, Barker DF, and Hein DW (2007) Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues. Drug Metab Dispos 35:721-727. (Pubitemid 46641541)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.5
, pp. 721-727
-
-
Husain, A.1
Zhang, X.2
Doll, M.A.3
States, J.C.4
Barker, D.F.5
Hein, D.W.6
-
20
-
-
40649109723
-
Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1
-
Kawamura A, Westwood I, Wakefield L, Long H, Zhang N, Walters K, Redfield C, and Sim E (2008) Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1. Biochem Pharmacol 75:1550-1560.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1550-1560
-
-
Kawamura, A.1
Westwood, I.2
Wakefield, L.3
Long, H.4
Zhang, N.5
Walters, K.6
Redfield, C.7
Sim, E.8
-
21
-
-
13844316753
-
Cytochrome P450 activation of arylamines and heterocyclic amines
-
DOI 10.1146/annurev.pharmtox.45.120403.100010
-
Kim D and Guengerich FP (2005) Cytochrome P450 activation of arylamines and heterocyclic amines. Annu Rev Pharmacol Toxicol 45:27-49. (Pubitemid 40261797)
-
(2005)
Annual Review of Pharmacology and Toxicology
, vol.45
, pp. 27-49
-
-
Kim, D.1
Guengerich, F.P.2
-
22
-
-
0032820660
-
CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice
-
DOI 10.1093/carcin/20.9.1825
-
Kimura S, Kawabe M, Ward JM, Morishima H, Kadlubar FF, Hammons GJ, Fernandez-Salguero P, and Gonzalez FJ (1999) CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl- induced hepatocarcinogenesis in mice. Carcinogenesis 20:1825-1830. (Pubitemid 29410564)
-
(1999)
Carcinogenesis
, vol.20
, Issue.9
, pp. 1825-1830
-
-
Kimura, S.1
Kawabe, M.2
Ward, J.M.3
Morishima, H.4
Kadlubar, F.F.5
Hammons, G.J.6
Fernandez-Salguero, P.7
Gonzalez, F.J.8
-
23
-
-
0345700808
-
Carcinogenesis of the food mutagen PhIP in mice is dependent of CYP1A2
-
DOI 10.1093/carcin/24.3.583
-
Kimura S, Kawabe M, Yu A, Morishima H, Fernandez-Salguero P, Hammons GJ, Ward JM, Kadlubar FF, and Gonzalez FJ (2003) Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2. Carcinogenesis 24:583-587. (Pubitemid 36432656)
-
(2003)
Carcinogenesis
, vol.24
, Issue.3
, pp. 583-587
-
-
Kimura, S.1
Kawabe, M.2
Yu, A.3
Morishima, H.4
Fernandez-Salguero, P.5
Hammons, G.J.6
Ward, J.M.7
Kadlubar, F.F.8
Gonzalez, F.J.9
-
24
-
-
77956925425
-
Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues
-
Lakics V, Karran EH, and Boess FG (2010) Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues. Neuropharmacology 59:367-374.
-
(2010)
Neuropharmacology
, vol.59
, pp. 367-374
-
-
Lakics, V.1
Karran, E.H.2
Boess, F.G.3
-
25
-
-
23744463885
-
Detailed review of transgenic rodent mutation assays
-
DOI 10.1016/j.mrrev.2005.04.002, PII S1383574205000384
-
Lambert IB, Singer TM, Boucher SE, and Douglas GR (2005) Detailed review of transgenic rodent mutation assays. Mutat Res 590:1-280. (Pubitemid 41121981)
-
(2005)
Mutation Research - Reviews in Mutation Research
, vol.590
, Issue.1-3
, pp. 1-280
-
-
Lambert, I.B.1
Singer, T.M.2
Boucher, S.E.3
Douglas, G.R.4
-
26
-
-
0032967592
-
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse
-
Leff MA, Epstein PN, Doll MA, Fretland AJ, Devanaboyina US, Rustan TD, and Hein DW (1999) Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse. J Pharmacol Exp Ther 290:182-187. (Pubitemid 29302318)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.1
, pp. 182-187
-
-
Leff, M.A.1
Epstein, P.N.2
Doll, M.A.3
Fretland, A.J.4
Devanaboyina, U.-S.5
Rustan, T.D.6
Hein, D.W.7
-
27
-
-
33751180365
-
N-Acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice
-
Loehle JA, Cornish V, Wakefield L, Doll MA, Neale JR, Zang Y, Sim E, and Hein DW (2006) N-Acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice. J Pharmacol Exp Ther 319:724-728.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 724-728
-
-
Loehle, J.A.1
Cornish, V.2
Wakefield, L.3
Doll, M.A.4
Neale, J.R.5
Zang, Y.6
Sim, E.7
Hein, D.W.8
-
28
-
-
79251542378
-
GSTM1 null and NAT2 slow acetylation genotypes, smoking intensity and bladder cancer risk: Results from the New England Bladder Cancer Study and NAT2 meta-analysis
-
Moore LE, Baris DR, Figueroa JD, Garcia-Closas M, Karagas MR, Schwenn MR, Johnson AT, Lubin JH, Hein DW, Dagnall CL, et al. (2011) GSTM1 null and NAT2 slow acetylation genotypes, smoking intensity and bladder cancer risk: Results from the New England Bladder Cancer Study and NAT2 meta-analysis. Carcinogenesis 32:182-189.
-
(2011)
Carcinogenesis
, vol.32
, pp. 182-189
-
-
Moore, L.E.1
Baris, D.R.2
Figueroa, J.D.3
Garcia-Closas, M.4
Karagas, M.R.5
Schwenn, M.R.6
Johnson, A.T.7
Lubin, J.H.8
Hein, D.W.9
Dagnall, C.L.10
-
29
-
-
33845267470
-
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
-
DOI 10.1038/nrc2015, PII NRC2015
-
Nebert DW and Dalton TP (2006) The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat Rev Cancer 6:947-960. (Pubitemid 44862679)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.12
, pp. 947-960
-
-
Nebert, D.W.1
Dalton, T.P.2
-
30
-
-
33947311640
-
Aromatic amines in experimental cancer research: Tissue-specific effects, an old problem and new solutions
-
Neumann HG (2007) Aromatic amines in experimental cancer research: Tissue-specific effects, an old problem and new solutions. Crit Rev Toxicol 37:211-236.
-
(2007)
Crit Rev Toxicol
, vol.37
, pp. 211-236
-
-
Neumann, H.G.1
-
31
-
-
67650439241
-
Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study
-
Nöthlings U, Yamamoto JF, Wilkens LR, Murphy SP, Park SY, Henderson BE, Kolonel LN, and Le Marchand L (2009) Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 18:2098-2106.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 2098-2106
-
-
Nöthlings, U.1
Yamamoto, J.F.2
Wilkens, L.R.3
Murphy, S.P.4
Park, S.Y.5
Henderson, B.E.6
Kolonel, L.N.7
Le Marchand, L.8
-
32
-
-
33847068206
-
Overview of PDEs and their regulation
-
Omori K and Kotera J (2007) Overview of PDEs and their regulation. Circ Res 100:309-327.
-
(2007)
Circ Res
, vol.100
, pp. 309-327
-
-
Omori, K.1
Kotera, J.2
-
33
-
-
0023339694
-
An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
-
Pinkert CA, Ornitz DM, Brinster RL, and Palmiter RD (1987) An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev 1:268-276.
-
(1987)
Genes Dev
, vol.1
, pp. 268-276
-
-
Pinkert, C.A.1
Ornitz, D.M.2
Brinster, R.L.3
Palmiter, R.D.4
-
34
-
-
76449120601
-
N-Acetyltransferase 2, exposure to aromatic and heterocyclic amines, and receptor-defined breast cancer
-
Rabstein S, Brüning T, Harth V, Fischer HP, Haas S, Weiss T, Spickenheuer A, Pierl C, Justenhoven C, Illig T, et al. (2010) N-Acetyltransferase 2, exposure to aromatic and heterocyclic amines, and receptor-defined breast cancer. Eur J Cancer Prev 19:100-109.
-
(2010)
Eur J Cancer Prev
, vol.19
, pp. 100-109
-
-
Rabstein, S.1
Brüning, T.2
Harth, V.3
Fischer, H.P.4
Haas, S.5
Weiss, T.6
Spickenheuer, A.7
Pierl, C.8
Justenhoven, C.9
Illig, T.10
-
35
-
-
77954516471
-
Well-done meat consumption, NAT1 and NAT2 acetylator genotypes and prostate cancer risk: The multiethnic cohort study
-
Sharma S, Cao X, Wilkens LR, Yamamoto J, Lum-Jones A, Henderson BE, Kolonel LN, and Le Marchand L (2010) Well-done meat consumption, NAT1 and NAT2 acetylator genotypes and prostate cancer risk: The multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 19:1866-1870.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 1866-1870
-
-
Sharma, S.1
Cao, X.2
Wilkens, L.R.3
Yamamoto, J.4
Lum-Jones, A.5
Henderson, B.E.6
Kolonel, L.N.7
Le Marchand, L.8
-
36
-
-
56349101750
-
Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms
-
Sim E, Lack N, Wang CJ, Long H, Westwood I, Fullam E, and Kawamura A (2008) Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms. Toxicology 254:170-183.
-
(2008)
Toxicology
, vol.254
, pp. 170-183
-
-
Sim, E.1
Lack, N.2
Wang, C.J.3
Long, H.4
Westwood, I.5
Fullam, E.6
Kawamura, A.7
-
38
-
-
0041886613
-
Analysis of aromatic amines in cigarette smoke
-
Stabbert R, Schäfer KH, Biefel C, and Rustemeier K (2003) Analysis of aromatic amines in cigarette smoke. Rapid Commun Mass Spectrom 17:2125-2132. (Pubitemid 37098328)
-
(2003)
Rapid Communications in Mass Spectrometry
, vol.17
, Issue.18
, pp. 2125-2132
-
-
Stabbert, R.1
Schafer, K.-H.2
Biefel, C.3
Rustemeier, K.4
-
39
-
-
33748886474
-
In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice
-
DOI 10.1124/dmd.106.010819
-
Sugamori KS, Brenneman D, and Grant DM (2006) In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. Drug Metab Dispos 34:1697-1702. (Pubitemid 44427472)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.10
, pp. 1697-1702
-
-
Sugamori, K.S.1
Brenneman, D.2
Grant, D.M.3
-
40
-
-
34250776519
-
Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse
-
DOI 10.1124/dmd.107.015396
-
Sugamori KS, Brenneman D, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, and Grant DM (2007) Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse. Drug Metab Dispos 35:1064-1070. (Pubitemid 46956425)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.7
, pp. 1064-1070
-
-
Sugamori, K.S.1
Brenneman, D.2
Wong, S.3
Gaedigk, A.4
Yu, V.5
Abramovici, H.6
Rozmahel, R.7
Grant, D.M.8
-
41
-
-
0037561531
-
Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
-
DOI 10.1124/mol.64.1.170
-
Sugamori KS, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, and Grant DM (2003) Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double- knockout mice. Mol Pharmacol 64:170-179. (Pubitemid 36759829)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.1
, pp. 170-179
-
-
Sugamori, K.S.1
Wong, S.2
Gaedigk, A.3
Yu, V.4
Abramovici, H.5
Rozmahel, R.6
Grant, D.M.7
-
42
-
-
4344574035
-
Near completely humanized liver in mice shows human-type metabolic responses to drugs
-
Tateno C, Yoshizane Y, Saito N, Kataoka M, Utoh R, Yamasaki C, Tachibana A, Soeno Y, Asahina K, Hino H, et al. (2004) Near completely humanized liver in mice shows human-type metabolic responses to drugs. Am J Pathol 165:901-912. (Pubitemid 39129297)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.3
, pp. 901-912
-
-
Tateno, C.1
Yoshizane, Y.2
Saito, N.3
Kataoka, M.4
Utoh, R.5
Yamasaki, C.6
Tachibana, A.7
Soeno, Y.8
Asahina, K.9
Hino, H.10
Asahara, T.11
Yokoi, T.12
Furukawa, T.13
Yoshizato, K.14
-
43
-
-
0041410080
-
4-Aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice
-
Tsuneoka Y, Dalton TP, Miller ML, Clay CD, Shertzer HG, Talaska G, Medvedovic M, and Nebert DW (2003) 4-Aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(-/-) mice. J Natl Cancer Inst 95:1227-1237. (Pubitemid 37069553)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.16
, pp. 1227-1237
-
-
Tsuneoka, Y.1
Dalton, T.P.2
Miller, M.L.3
Clay, C.D.4
Shertzer, H.G.5
Talaska, G.6
Medvedovic, M.7
Nebert, D.W.8
-
44
-
-
2142695286
-
Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation
-
DOI 10.1124/mol.65.5.1225
-
Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, and Nebert DW (2004) Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation. Mol Pharmacol 65:1225-1237. (Pubitemid 38543493)
-
(2004)
Molecular Pharmacology
, vol.65
, Issue.5
, pp. 1225-1237
-
-
Uno, S.1
Dalton, T.P.2
Derkenne, S.3
Curran, C.P.4
Miller, M.L.5
Shertzer, H.G.6
Nebert, D.W.7
-
45
-
-
26244451398
-
Gender-dependent hepatic alterations in H-ras12V transgenic mice
-
DOI 10.1016/j.jhep.2005.04.012, PII S0168827805003314
-
Wang AG, Moon HB, Lee MR, Hwang CY, Kwon KS, Yu SL, Kim YS, Kim M, Kim JM, Kim SK, et al. (2005) Gender-dependent hepatic alterations in H-ras12V transgenic mice. J Hepatol 43:836-844. (Pubitemid 41414510)
-
(2005)
Journal of Hepatology
, vol.43
, Issue.5
, pp. 836-844
-
-
Wang, A.-G.1
Moon, H.-B.2
Lee, M.-R.3
Hwang, C.Y.4
Kwon, K.-S.5
Yu, S.-L.6
Kim, Y.-S.7
Kim, M.8
Kim, J.-M.9
Kim, S.-K.10
Lee, T.-H.11
Moon, E.-Y.12
Lee, D.-S.13
Yu, D.-Y.14
|