Sexual behaviors over a 3-year period among individuals with advanced HIV/AIDS receiving antiretroviral therapy in an Urban HIV clinic in Kampala, Uganda

Journal of Acquired Immune Deficiency Syndromes

Volumn 57, Issue 1, 2011, Pages 62-68

  Wandera, Bonnie ^a   Kamya, Moses R ^b   Castelnuovo, Barbara ^a   Kiragga, Agnes ^a   Kambugu, Andrew ^a   Wanyama, Jane N ^a   Easterbrook, Philippa ^a   Sethi, Ajay K ^c  

^a Infectious Diseases Institute   (Uganda)

^b MAKERERE UNIVERSITY   (Uganda)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

antiretroviral therapy; condom use; HIV AIDS; positive prevention; sexual behavior; Uganda; unprotected sex

Indexed keywords

ANTIRETROVIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; FEMALE; HIGH RISK BEHAVIOR; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MARRIAGE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEXUAL BEHAVIOR; UGANDA; UNSAFE SEX; VIRUS LOAD;

ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; PREVALENCE; PROSPECTIVE STUDIES; QUESTIONNAIRES; REGRESSION ANALYSIS; SEXUAL BEHAVIOR; SOCIOECONOMIC FACTORS; UGANDA; URBAN POPULATION;

EID: 79955030142     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318211b3f2     Document Type: Article

References (47)

1. Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338: 853-860. (Pubitemid 28135961)
2. Mocroft A, Vella S, Benfield TL, et al. Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group. Lancet. 1998;352:1725-1730. (Pubitemid 28534954)
3. Lorenz KA, Cunningham WE, Spritzer KL, et al. Changes in symptoms and health-related quality of life in a nationally representative sample of adults in treatment for HIV. Qual Life Res. 2006;15:951-958. (Pubitemid 44221449)
4. Wouters E, Heunis C, van Rensburg D, et al. Physical and emotional health outcomes after 12 months of public-sector antiretroviral treatment in the Free State Province of South Africa: a longitudinal study using structural equation modelling. BMC Public Health. 2009;9:103.
5. Spacek LA, Shihab HM, Kamya MR, et al. Response to antiretroviral therapy in HIV-infected patients attending a public, urban clinic in Kampala, Uganda. Clin Infect Dis. 2006;42:252-259. (Pubitemid 43054199)
6. Wester CW, Bussmann H, Koethe J, et al. Adult combination antiretroviral therapy in sub-Saharan Africa: lessons from Botswana and future challenges. HIV Ther. 2009;3:501-526.
7. Coetzee D, Hildebrand K, Boulle A, et al. Outcomes after two years of providing antiretroviral treatment in Khayelitsha, South Africa. AIDS. 2004;18:887-895. (Pubitemid 38553709)
8. Dukers NH, Goudsmit J, de Wit JB, et al. Sexual risk behaviour relates to the virological and immunological improvements during highly active antiretroviral therapy in HIV-1 infection. AIDS. 2001;15:369-378. (Pubitemid 32163823)
9. Dilley JW, Woods WJ, McFarland W. Are advances in treatment changing views about high-risk sex? N Engl J Med. 1997;337:501-502. (Pubitemid 27333058)
10. Ostrow DE, Fox KJ, Chmiel JS, et al. Attitudes towards highly active antiretroviral therapy are associated with sexual risk taking among HIV-infected and uninfected homosexual men. AIDS. 2002;16: 775-780. (Pubitemid 34274468)
11. Stolte IG, Dukers NH, Geskus RB, et al. Homosexual men change to risky sex when perceiving less threat of HIV/AIDS since availability of highly active antiretroviral therapy: a longitudinal study. AIDS. 2004;18: 303-309. (Pubitemid 38253454)
12. Crepaz N, Hart TA, Marks G. Highly active antiretroviral therapy and sexual risk behavior: a meta-analytic review. JAMA. 2004;292:224-236. (Pubitemid 38918000)
13. Martin Hilber A, Hull TH, Preston-Whyte E, et al. A cross cultural study of vaginal practices and sexuality: Implications for sexual health. Soc Sci Med. 2009;9:9.
14. Kennedy C, O'Reilly K, Medley A, et al. The impact of HIV treatment on risk behaviour in developing countries: a systematic review. AIDS Care. 2007;19:707-720. (Pubitemid 46944272)
15. Kamya MR, Mayanja-Kizza H, Kambugu A, et al. Predictors of long-term viral failure among Ugandan children and adults treated with antiretroviral therapy. J Acquir Immune Defic Syndr. 2007;46:187-193. (Pubitemid 47482614)
16. World Health Organization. Scaling Up Antiretroviral Therapy in Resource Limited Settings. Guidelines for a Public Health Approach. Geneva: WHO; 2002.
17. Zou G. A modified Poisson regression approach to prospective studies with binary data. Am J Epidemiol. 2004;159:702-706. (Pubitemid 38405384)
18. Attia S, Egger M, Muller M, et al. Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis. AIDS. 2009;23:1397-1404.
19. Castelnuovo B, Manabe YC, Kiragga A, et al. Cause-specific mortality and the contribution of immune reconstitution inflammatory syndrome in the first 3 years after antiretroviral therapy initiation in an urban African cohort. Clin Infect Dis. 2009;49:965-972.
20. Marshall BD, Milloy MJ, Kerr T, et al. No evidence of increased sexual risk behaviour after initiating antiretroviral therapy among people who inject drugs. AIDS. 2010;24:2271-2278.
21. Atuyambe L, Neema S, Otolok-Tanga E, et al. The effects of enhanced access to antiretroviral therapy: a qualitative study of community perceptions in Kampala city, Uganda. Afr Health Sci. 2008;8:13-19.
22. Moatti JP, Prudhomme J, Traore DC, et al. Access to antiretroviral treatment and sexual behaviours of HIV-infected patients aware of their serostatus in Cote d'Ivoire. AIDS. 2003;17(Suppl 3):S69-S77. (Pubitemid 36951672)
23. Bateganya M, Colfax G, Shafer LA, et al. Antiretroviral therapy and sexual behavior: a comparative study between antiretroviral- naive and -experienced patients at an urban HIV/AIDS care and research center in Kampala, Uganda. AIDS Patient Care STDs. 2005;19:760-768. (Pubitemid 41705172)
24. Bunnell R, Opio A, Musinguzi J, et al. HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey. AIDS. 2008;22:617-624. (Pubitemid 351640594)
25. Bechange S, Bunnell R, Awor A, et al. Two-year follow-up of sexual behavior among HIV-uninfected household members of adults taking antiretroviral therapy in Uganda: no evidence of disinhibition. AIDS Behav. 2008;24:24.
26. Stockman JK, Schwarcz SK, Butler LM, et al. HIV prevention fatigue among high-risk populations in San Francisco. J Acquir Immune Defic Syndr. 2004;35:432-434. (Pubitemid 38332807)
27. Venkatesh KK, de Bruyn G, Lurie MN, et al. Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics. AIDS. 2010:31:2687-2696.
28. Sarna A, Luchters SM, Geibel S, et al. Sexual risk behaviour and HAART: a comparative study of HIV-infected persons on HAART and on preventive therapy in Kenya. Int J STD AIDS. 2008;19:85-89. (Pubitemid 351738811)
29. Maman S, Mbwambo JK, Hogan NM, et al. High rates and positive outcomes of HIV-serostatus disclosure to sexual partners: reasons for cautious optimism from a voluntary counseling and testing clinic in Dar es Salaam, Tanzania. AIDS Behav. 2003;7:373-382. (Pubitemid 38005000)
30. Maman S, Mbwambo J, Hogan NM, et al. Women's barriers to HIV-1 testing and disclosure: challenges for HIV-1 voluntary counselling and testing. AIDS Care. 2001;13:595-603. (Pubitemid 32928067)
31. Sullivan KM. Male self-disclosure of HIV-positive serostatus to sex partners: a review of the literature. J Assoc Nurses AIDS Care. 2005;16:33-47. (Pubitemid 43339108)
32. Hakim Sendagire BC, Kiragga A, Kambugu A, et al. CDB029- Factors Associated With Increasing HIV-1 Resistance to Antiretroviral Therapy in an Urban Cohort in Kampala, Uganda. 5th IAS Conference on HIV Pathogenesis Treatment and Prevention; Cape Town; 2009.
33. Schroder KE, Carey MP, Vanable PA. Methodological challenges in research on sexual risk behavior: II. Accuracy of self-reports. Ann Behav Med. 2003;26:104-123. (Pubitemid 37271597)
34. Shannon K, Strathdee SA, Shoveller J, et al. Structural and environmental barriers to condom use negotiation with clients among female sex workers: implications for HIV-prevention strategies and policy. Am J Public Health. 2009;99:659-665.
35. Lifshay J, Nakayiwa S, King R, et al. Partners at risk: motivations, strategies, and challenges to HIV transmission risk reduction among HIV-infected men and women in Uganda. AIDS Care. 2009;29:1-10.
36. Stevens PE, Galvao L. 'He Won't Use Condoms': HIV-infected women's struggles in primary relationships with serodiscordant partners. Am J Public Health. 2007;97:1015-1022. (Pubitemid 351181921)
37. Graham CA, Crosby RA, Sanders SA, et al. Assessment of condom use in men and women. Annu Rev Sex Res. 2005;16:20-52. (Pubitemid 43836773)
38. Spire B, de Zoysa I, Himmich H. HIV prevention: what have we learned from community experiences in concentrated epidemics? J Int AIDS Soc. 2008;11:5.
39. Auerbach JD, Coates TJ. HIV prevention research: accomplishments and challenges for the third decade of AIDS. Am J Public Health. 2000;90: 1029-1032. (Pubitemid 30445353)
40. Salomon JA, Hogan DR, Stover J, et al. Integrating HIV prevention and treatment: from slogans to impact. PLoS Med. 2005;2:e16.
41. Baggaley RF, Garnett GP, Ferguson NM. Modelling the impact of antiretroviral use in resource-poor settings. PLoS Med. 2006;3:e124.
42. Anand A, Shiraishi RW, Bunnell RE, et al. Knowledge of HIV status, sexual risk behaviors and contraceptive need among people living with HIV in Kenya and Malawi. AIDS. 2009;23:1565-1573.
43. Wingood GM, DiClemente RJ, Mikhail I, et al. A randomized controlled trial to reduce HIV transmission risk behaviors and sexually transmitted diseases among women living with HIV: the WiLLOW Program. J Acquir Immune Defic Syndr. 2004;37(Suppl 2):S58-S67.
44. Kalichman SC, Rompa D, Cage M, et al. Effectiveness of an intervention to reduce HIV transmission risks in HIV-positive people. Am J Prev Med. 2001;21:84-92. (Pubitemid 32660421)
45. Crepaz N, Lyles CM, Wolitski RJ, et al. Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials. AIDS. 2006;20:143-157.
46. Lightfoot M, Rotheram-Borus MJ, Comulada WS, et al. Efficacy of brief interventions in clinical care settings for persons living with HIV. J Acquir Immune Defic Syndr. 2009;8:8.
47. Rotheram-Borus MJ, Swendeman D, Comulada WS, et al. Prevention for substance-using HIV-positive young people: telephone and in-person delivery. J Acquir Immune Defic Syndr. 2004;37(Suppl 2): S68-S77.