-
1
-
-
27744562232
-
Differential antitumor immunity mediated by NKT cell subsets in vivo
-
DOI 10.1084/jem.20050953
-
Crowe NY, et al. (2005) Differential antitumor immunity mediated by NKT cell subsets in vivo. J Exp Med 202:1279-1288. (Pubitemid 41586958)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1279-1288
-
-
Crowe, N.Y.1
Coquet, J.M.2
Berzins, S.P.3
Kyparissoudis, K.4
Keating, R.5
Pellicci, D.G.6
Hayakawa, Y.7
Godfrey, D.I.8
Smyth, M.J.9
-
3
-
-
0035951445
-
Glycolipid antigen processing for presentation by CD1d molecules
-
DOI 10.1126/science.291.5504.664
-
Prigozy TI, et al. (2001) Glycolipid antigen processing for presentation by CD1d molecules. Science 291:664-667. (Pubitemid 32150427)
-
(2001)
Science
, vol.291
, Issue.5504
, pp. 664-667
-
-
Prigozy, T.I.1
Naidenko, O.2
Qasba, P.3
Elewaut, D.4
Brossay, L.5
Khurana, A.6
Natori, T.7
Koezuka, Y.8
Kulkarni, A.9
Kronenberg, M.10
-
4
-
-
0028863822
-
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes
-
Bendelac A (1995) Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med 182:2091-2096.
-
(1995)
J Exp Med
, vol.182
, pp. 2091-2096
-
-
Bendelac, A.1
-
5
-
-
10044280324
-
Lysosomal glycosphingolipid recognition by NKT cells
-
DOI 10.1126/science.1103440
-
Zhou D, et al. (2004) Lysosomal glycosphingolipid recognition by NKT cells. Science 306:1786-1789. (Pubitemid 39601398)
-
(2004)
Science
, vol.306
, Issue.5702
, pp. 1786-1789
-
-
Zhou, D.1
Mattner, J.2
Cantu III, C.3
Schrantz, N.4
Yin, N.5
Gao, Y.6
Sagiv, Y.7
Hudspeth, K.8
Wu, Y.-P.9
Yamashita, T.10
Teneberg, S.11
Wang, D.12
Proia, R.L.13
Levery, S.B.14
Savage, P.B.15
Teyton, L.16
Bendelac, A.17
-
6
-
-
34247592222
-
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
-
DOI 10.1073/pnas.0611139104
-
Porubsky S, et al. (2007) Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency. Proc Natl Acad Sci USA 104:5977-5982. (Pubitemid 47175644)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.14
, pp. 5977-5982
-
-
Porubsky, S.1
Speak, A.O.2
Luckow, B.3
Cerundolo, V.4
Platt, F.M.5
Grone, H.-J.6
-
7
-
-
48349111099
-
Humans lack iGb3 due to the absence of functional iGb3- synthase: Implications for NKT cell development and transplantation
-
Christiansen D, et al. (2008) Humans lack iGb3 due to the absence of functional iGb3- synthase: Implications for NKT cell development and transplantation. PLoS Biol 6: e172.
-
(2008)
PLoS Biol
, vol.6
-
-
Christiansen, D.1
-
8
-
-
0025897376
-
Saposin proteins: Structure, function, and role in human lysosomal storage disorders
-
O'Brien JS, Kishimoto Y (1991) Saposin proteins: Structure, function, and role in human lysosomal storage disorders. FASEB J 5:301-308. (Pubitemid 21892890)
-
(1991)
FASEB Journal
, vol.5
, Issue.3
, pp. 301-308
-
-
O'Brien, J.S.1
Kishimoto, Y.2
-
9
-
-
0042667012
-
Structural analysis of lipid complexes of GM2-activator protein
-
DOI 10.1016/S0022-2836(03)00794-0
-
Wright CS, Zhao Q, Rastinejad F (2003) Structural analysis of lipid complexes of GM2- activator protein. J Mol Biol 331:951-964. (Pubitemid 36945447)
-
(2003)
Journal of Molecular Biology
, vol.331
, Issue.4
, pp. 951-964
-
-
Wright, C.S.1
Zhao, Q.2
Rastinejad, F.3
-
10
-
-
19244385377
-
Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): Its mechanism and inhibition by ganglioside
-
DOI 10.1006/abbi.1997.9958
-
Hiraiwa M, et al. (1997) Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): its mechanism and inhibition by ganglioside. Arch Biochem Biophys 341:17-24. (Pubitemid 27198026)
-
(1997)
Archives of Biochemistry and Biophysics
, vol.341
, Issue.1
, pp. 17-24
-
-
Hiraiwa, M.1
Martin, B.M.2
Kishimoto, Y.3
Conner, G.E.4
Tsuji, S.5
O'Brien, J.S.6
-
11
-
-
1142263116
-
Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells
-
DOI 10.1038/ni1034
-
Kang SJ, Cresswell P (2004) Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells. Nat Immunol 5:175-181. (Pubitemid 38208359)
-
(2004)
Nature Immunology
, vol.5
, Issue.2
, pp. 175-181
-
-
Kang, S.-J.1
Cresswell, P.2
-
12
-
-
77953499076
-
Multi-system disorders of glycosphingolipid and ganglioside metabolism
-
Xu YH, Barnes S, Sun Y, Grabowski GA (2010) Multi-system disorders of glycosphingolipid and ganglioside metabolism. J Lipid Res 51:1643-1675.
-
(2010)
J Lipid Res
, vol.51
, pp. 1643-1675
-
-
Xu, Y.H.1
Barnes, S.2
Sun, Y.3
Grabowski, G.A.4
-
13
-
-
35248814255
-
The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease
-
DOI 10.1007/s10545-007-0632-9
-
Schuchman EH (2007) The pathogenesis and treatment of acid sphingomyelinasedeficient Niemann-Pick disease. J Inherit Metab Dis 30:654-663. (Pubitemid 47559876)
-
(2007)
Journal of Inherited Metabolic Disease
, vol.30
, Issue.5
, pp. 654-663
-
-
Schuchman, E.H.1
-
14
-
-
17144413846
-
Signaling for NKT cell development: The SAP-FynT connection
-
DOI 10.1084/jem.20050339
-
Borowski C, Bendelac A (2005) Signaling for NKT cell development: The SAP-FynT connection. J Exp Med 201:833-836. (Pubitemid 40524451)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.6
, pp. 833-836
-
-
Borowski, C.1
Bendelac, A.2
-
16
-
-
1842785209
-
T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells
-
DOI 10.1016/S1074-7613(04)00076-7, PII S1074761304000767
-
Townsend MJ, et al. (2004) T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity 20:477-494. (Pubitemid 38482125)
-
(2004)
Immunity
, vol.20
, Issue.4
, pp. 477-494
-
-
Townsend, M.J.1
Weinmann, A.S.2
Matsuda, J.L.3
Salomon, R.4
Farnham, P.J.5
Biron, C.A.6
Gapin, L.7
Glimcher, L.H.8
-
18
-
-
0032536787
-
+ T) cells, natural killer cells, and intestinal intraepithelial T cells
-
DOI 10.1084/jem.187.6.967
-
Ohteki T, et al. (1998) The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells. J Exp Med 187: 967-972. (Pubitemid 28141670)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.6
, pp. 967-972
-
-
Ohteki, T.1
Yoshida, H.2
Matsuyama, T.3
Duncan, G.S.4
Mak, T.W.5
Ohashi, P.S.6
-
19
-
-
20444493969
-
Genetic evidence supporting selection of the Vα14i NKT cell lineage from double-positive thymocyte precursors
-
DOI 10.1016/j.immuni.2005.03.011, PII S1074761305001068
-
Egawa T, et al. (2005) Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors. Immunity 22:705-716. (Pubitemid 40814501)
-
(2005)
Immunity
, vol.22
, Issue.6
, pp. 705-716
-
-
Egawa, T.1
Eberl, G.2
Taniuchi, I.3
Benlagha, K.4
Geissmann, F.5
Hennighausen, L.6
Bendelac, A.7
Littman, D.R.8
-
20
-
-
0034653452
-
Cutting edge: The Ets1 transcription factor is required for the development of NK T cells in mice
-
Walunas TL, Wang B, Wang CR, Leiden JM (2000) Cutting edge: The Ets1 transcription factor is required for the development of NK T cells in mice. J Immunol 164: 2857-2860. (Pubitemid 30148940)
-
(2000)
Journal of Immunology
, vol.164
, Issue.6
, pp. 2857-2860
-
-
Walunas, T.L.1
Wang, B.2
Wang, C.-R.3
Leiden, J.M.4
-
21
-
-
60749112787
-
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
-
Lazarevic V, et al. (2009) The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol 10:306-313.
-
(2009)
Nat Immunol
, vol.10
, pp. 306-313
-
-
Lazarevic, V.1
-
22
-
-
0038544245
-
Differential requirement for Rel/nuclear factor kB family members in natural killer T cell development
-
DOI 10.1084/jem.20022234
-
Sivakumar V, Hammond KJ, Howells N, Pfeffer K, Weih F (2003) Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development. J Exp Med 197:1613-1621. (Pubitemid 36745337)
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.12
, pp. 1613-1621
-
-
Sivakumar, V.1
Hammond, K.J.L.2
Howells, N.3
Pfeffer, K.4
Welh, F.5
-
23
-
-
50049084627
-
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions
-
Kovalovsky D, et al. (2008) The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol 9: 1055-1064.
-
(2008)
Nat Immunol
, vol.9
, pp. 1055-1064
-
-
Kovalovsky, D.1
-
24
-
-
51349121407
-
The transcription factor PLZF directs the effector program of the NKT cell lineage
-
Savage AK, et al. (2008) The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 29:391-403.
-
(2008)
Immunity
, vol.29
, pp. 391-403
-
-
Savage, A.K.1
-
25
-
-
66649128115
-
Intrathymic proliferation wave essential for V{alpha}14+ natural killer T cell development depends on c-Myc
-
Dose M, et al. (2009) Intrathymic proliferation wave essential for V{alpha}14+ natural killer T cell development depends on c-Myc. Proc Natl Acad Sci USA 106:8641-8646.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8641-8646
-
-
Dose, M.1
-
26
-
-
0034616171
-
2 zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors
-
DOI 10.1074/jbc.275.14.10315
-
Avram D, et al. (2000) Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J Biol Chem 275: 10315-10322. (Pubitemid 30202090)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.14
, pp. 10315-10322
-
-
Avram, D.1
Fields, A.2
Pretty On Top, K.3
Nevrivy, D.J.4
Ishmael, J.E.5
Leid, M.6
-
27
-
-
0036901409
-
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein
-
DOI 10.1042/BJ20020496
-
Avram D, Fields A, Senawong T, Topark-Ngarm A, Leid M (2002) COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. Biochem J 368:555-563. (Pubitemid 35454533)
-
(2002)
Biochemical Journal
, vol.368
, Issue.2
, pp. 555-563
-
-
Avram, D.1
Fields, A.2
Senawong, T.3
Topark-Ngarm, A.4
Leid, M.5
-
28
-
-
27144528261
-
BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter
-
DOI 10.1038/sj.onc.1208904, PII 1208904
-
Cismasiu VB, et al. (2005) BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter. Oncogene 24:6753-6764. (Pubitemid 41487034)
-
(2005)
Oncogene
, vol.24
, Issue.45
, pp. 6753-6764
-
-
Cismasiu, V.B.1
Adamo, K.2
Gecewicz, J.3
Duque, J.4
Lin, Q.5
Avram, D.6
-
29
-
-
33750607751
-
BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes
-
Cismasiu VB, et al. (2006) BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes. Blood 108:2695-2702.
-
(2006)
Blood
, vol.108
, pp. 2695-2702
-
-
Cismasiu, V.B.1
-
30
-
-
36549090422
-
BCL11B is required for positive selection and survival of double-positive thymocytes
-
DOI 10.1084/jem.20070863
-
Albu DI, et al. (2007) BCL11B is required for positive selection and survival of doublepositive thymocytes. J Exp Med 204:3003-3015. (Pubitemid 350179567)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.12
, pp. 3003-3015
-
-
Albu, D.I.1
Feng, D.2
Bhattacharya, D.3
Jenkins, N.A.4
Copeland, N.G.5
Liu, P.6
Avram, D.7
-
31
-
-
53249151597
-
BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complex
-
Cismasiu VB, et al. (2008) BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complex. Virology 380:173-181.
-
(2008)
Virology
, vol.380
, pp. 173-181
-
-
Cismasiu, V.B.1
-
32
-
-
58249087316
-
BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes
-
Cismasiu VB, et al. (2009) BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes. Biochem J 417:457-466.
-
(2009)
Biochem J
, vol.417
, pp. 457-466
-
-
Cismasiu, V.B.1
-
33
-
-
84934441436
-
Flow cytometry analysis of transcription factors in T lymphocytes
-
Albu DI, Califano D, Avram D (2010) Flow cytometry analysis of transcription factors in T lymphocytes. Methods Mol Biol 647:377-390.
-
(2010)
Methods Mol Biol
, vol.647
, pp. 377-390
-
-
Albu, D.I.1
Califano, D.2
Avram, D.3
-
34
-
-
77954329976
-
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b
-
Li L, Leid M, Rothenberg EV (2010) An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science 329:89-93.
-
(2010)
Science
, vol.329
, pp. 89-93
-
-
Li, L.1
Leid, M.2
Rothenberg, E.V.3
-
35
-
-
77954321988
-
An essential developmental checkpoint for production of the T cell lineage
-
Ikawa T, et al. (2010) An essential developmental checkpoint for production of the T cell lineage. Science 329:93-96.
-
(2010)
Science
, vol.329
, pp. 93-96
-
-
Ikawa, T.1
-
36
-
-
77954326626
-
Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion
-
Li P, et al. (2010) Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science 329:85-89.
-
(2010)
Science
, vol.329
, pp. 85-89
-
-
Li, P.1
-
37
-
-
77955346275
-
Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b
-
Zhang S, et al. (2010) Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b. J Exp Med 207: 1687-1699.
-
(2010)
J Exp Med
, vol.207
, pp. 1687-1699
-
-
Zhang, S.1
-
38
-
-
77956119990
-
Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes
-
Kastner P, et al. (2010) Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes. Eur J Immunol 40:2143-2145.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2143-2145
-
-
Kastner, P.1
-
39
-
-
0033521624
-
Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments
-
Chiu YH, et al. (1999) Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J Exp Med 189:103-110.
-
(1999)
J Exp Med
, vol.189
, pp. 103-110
-
-
Chiu, Y.H.1
-
40
-
-
33745291927
-
Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick Type C1 protein
-
Sagiv Y, et al. (2006) Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein. J Immunol 177:26-30. (Pubitemid 43939110)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 26-30
-
-
Sagiv, Y.1
Hudspeth, K.2
Mattner, J.3
Schrantz, N.4
Stern, R.K.5
Zhou, D.6
Savage, P.B.7
Teyton, L.8
Bendelac, A.9
-
41
-
-
34247325926
-
The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells
-
DOI 10.1084/jem.20061562
-
Schrantz N, et al. (2007) The Niemann-Pick type C2 protein loads isoglobotrihexosylceramide onto CD1d molecules and contributes to the thymic selection of NKT cells. J Exp Med 204:841-852. (Pubitemid 46631613)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.4
, pp. 841-852
-
-
Schrantz, N.1
Sagiv, Y.2
Liu, Y.3
Savage, P.B.4
Bendelac, A.5
Teyton, L.6
-
42
-
-
0036853166
-
Thymocyte expression of cathepsin L is essential for NKT cell development
-
DOI 10.1038/ni844
-
Honey K, et al. (2002) Thymocyte expression of cathepsin L is essential for NKT cell development. Nat Immunol 3:1069-1074. (Pubitemid 35363660)
-
(2002)
Nature Immunology
, vol.3
, Issue.11
, pp. 1069-1074
-
-
Honey, K.1
Benlagha, K.2
Beers, C.3
Forbush, K.4
Teyton, L.5
Kleijmeer, M.J.6
Rudensky, A.Y.7
Bendelac, A.8
-
43
-
-
0022363067
-
Lack of acid sphingomyelinase in the mitochondria-lysosome fraction of brain from Niemann-Pick mice
-
DOI 10.1007/BF01819301
-
Tsuda M, Owada M, Kitagawa T, Miyawaki S (1985) Lack of acid sphingomyelinase in the mitochondria-lysosome fraction of brain from Niemann-Pick mice. J Inherit Metab Dis 8:147-148. (Pubitemid 15227175)
-
(1985)
Journal of Inherited Metabolic Disease
, vol.8
, Issue.3
, pp. 147-148
-
-
Tsuda, M.1
Owada, M.2
Kitagawa, T.3
Miyawaki, S.4
-
44
-
-
67749101342
-
GM1 gangliosidosis and Morquio B disease: Expression analysis of missense mutations affecting the catalytic site of acid beta-galactosidase
-
Hofer D, et al. (2009) GM1 gangliosidosis and Morquio B disease: Expression analysis of missense mutations affecting the catalytic site of acid beta-galactosidase. Hum Mutat 30:1214-1221.
-
(2009)
Hum Mutat
, vol.30
, pp. 1214-1221
-
-
Hofer, D.1
-
46
-
-
38349029763
-
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum
-
DOI 10.1523/JNEUROSCI.2986-07.2008
-
Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD (2008) Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci 28:622-632. (Pubitemid 351159027)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.3
, pp. 622-632
-
-
Arlotta, P.1
Molyneaux, B.J.2
Jabaudon, D.3
Yoshida, Y.4
Macklis, J.D.5
-
47
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
|