CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion

International Journal of Oncology

Volumn 38, Issue 5, 2011, Pages 1279-1285

  Johnson Holiday, Crystal ^a   Singh, Rajesh ^a   Johnson, Erica ^a   Singh, Shailesh ^a   Stockard, Cecil R ^b   Grizzle, William E ^b   Lillard Jr , James W ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Chemokine; Immunobiology; Matrix metalloproteinase

Indexed keywords

CCL25; CHEMOKINE RECEPTOR CCR9; COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; LIGAND; STROMELYSIN; STROMELYSIN 2; STROMELYSIN 3; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINES, CC; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASES; NEOPLASM INVASIVENESS; RECEPTORS, CCR;

EID: 79955003403     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.953     Document Type: Article

References (41)

1. Gonzalez-Angulo AM, Morales-Vasquez F and Hortobagyi GN: Overview of resistance to systemic therapy in patients with breast cancer. Adv Exp Med Biol 608: 1-22, 2007.
2. Nicolson GL: Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites. Cancer Metastasis Rev 7: 143-188, 1988.
3. Chambers AF, Groom AC and MacDonald IC: Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2: 563-572, 2002.
4. Patanaphan V, Salazar OM and Risco R: Breast cancer: metastatic patterns and their prognosis. South Med J 81: 1109-1112, 1988.
5. Muller A, Homey B, Soto H, et al: Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56, 2001. (Pubitemid 32225831)
6. David R and Marelli-Berg FM: Regulation of T-cell migration by co-stimulatory molecules. Biochem Soc Trans 35: 1114-1118, 2007. (Pubitemid 350206441)
7. Trentin L, Miorin M, Facco M, et al: Multiple myeloma plasma cells show different chemokine receptor profiles at sites of disease activity. Br J Haematol 138: 594-602, 2007. (Pubitemid 47206713)
8. Gomperts BN and Strieter RM: Chemokine-directed metastasis. Contrib Microbiol 13: 170-190, 2006.
9. Singh S, Singh UP, Grizzle WE and Lillard JW: CXCL12- CXCR4 interactions modulates prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest 84: 1666-1676, 2004. (Pubitemid 39600573)
10. Cabioglu N, Gong Y, Islam R, et al: Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancer. Ann Oncol 18: 1021-1029, 2007. (Pubitemid 47050493)
11. Cabioglu N, Yazici MS, Arun B, et al: CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer. Clin Cancer Res 11: 5686-5693, 2005. (Pubitemid 41170291)
12. Moore MA: The role of chemoattraction in cancer metastases. Bioessays 23: 674-676, 2001.
13. Miao Z, Luker KE, Summers BC, et al: CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci USA 104: 15735-15740, 2007. (Pubitemid 350035369)
14. Meijer J, Ogink J and Roos E: Effect of the chemokine receptor CXCR7 on proliferation of carcinoma cells in vitro and in vivo. Br J Cancer 99: 1493-1501, 2008.
15. Hwang ST: Chemokine receptors in melanoma: CCR9 has a potential role in metastasis to the small bowel. J Invest Dermatol 122: xiv-xv, 2004.
16. Wurbel MA, Malissen M, Guy-Grand D, et al: Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes. Blood 98: 2626-2632, 2001.
17. Wurbel MA, Philippe JM, Nguyen C, et al: The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur J Immunol 30: 262-271, 2000. (Pubitemid 30011788)
18. Papadakis KA, Prehn J, Nelson V, et al: The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J Immunol 165: 5069-5076, 2000.
19. Elgueta R, Sepulveda FE, Vilches F, et al: Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells. J Immunol 180: 6501-6507, 2008.
20. Asch MJ, Wiedel PD and Habif DV: Gastrointestinal metastases from carcinoma of the breast. Autopsy study and 18 cases requiring operative intervention. Arch Surg 96: 840-843, 1968.
21. Birla R, Mahawar KK, Orizu M, Siddiqui MS and Batra A: Caecal metastasis from breast cancer presenting as intestinal obstruction. World J Surg Oncol 6: 47, 2008.
22. Cifuentes N and Pickren JW: Metastases from carcinoma of mammary gland: an autopsy study. J Surg Oncol 11: 193-205, 1979. (Pubitemid 9182353)
23. Hata K, Kitayama J, Shinozaki M, et al: Intestinal perforation due to metastasis of breast carcinoma, with special reference to chemotherapy: a case report. Jpn J Clin Oncol 31: 162-164, 2001. (Pubitemid 32529765)
24. + T cells from secondary lymphoid organs. Blood 97: 850-857, 2001.
25. Fox BP and Kandpal RP: Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application. Biochem Biophys Res Commun 318: 882-892, 2004. (Pubitemid 38625856)
26. Fritah A, Saucier C, De Wever O, et al: Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells. Mol Cell Biol 28: 1114-1123, 2008. (Pubitemid 351160067)
27. Youn BS, Yu KY, Oh J, Lee J, Lee TH and Broxmeyer HE: Role of the CC chemokine receptor 9/TECK interaction in apoptosis. Apoptosis 7: 271-276, 2002. (Pubitemid 34633467)
28. Lievre A, Milet J, Carayol J, et al: Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma. BMC Cancer 6: 270, 2006.
29. Woo M, Park K, Nam J and Kim JC: Clinical implications of matrix metalloproteinase-1, -3, -7, -9, -12, and plasminogen activator inhibitor-1 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 22: 1064-1070, 2007. (Pubitemid 47019841)
30. Gu ZD, Li JY, Li M, et al: Matrix metalloproteinases expression correlates with survival in patients with esophageal squamous cell carcinoma. Am J Gastroenterol 100: 1835-1843, 2005.
31. Kader AK, Liu J, Shao L, et al: Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness. Clin Cancer Res 13: 2614-2620, 2007. (Pubitemid 46788027)
32. Nutt JE, Mellon JK, Qureshi K and Lunec J: Matrix metalloproteinase- 1 is induced by epidermal growth factor in human bladder tumour cell lines and is detectable in urine of patients with bladder tumours. Br J Cancer 78: 215-220, 1998. (Pubitemid 28302259)
33. Nutt JE and Lunec J: Induction of metalloproteinase (MMP1) expression by epidermal growth factor (EGF) receptor stimulation and serum deprivation in human breast tumour cells. Eur J Cancer 32A: 2127-2135, 1996. (Pubitemid 26419464)
34. Culhaci N, Metin K, Copcu E and Dikicioglu E: Elevated expression of MMP-13 and TIMP-1 in head and neck squamous cell carcinomas may reflect increased tumor invasiveness. BMC Cancer 4: 42, 2004.
35. Li HC, Cao DC, Liu Y, et al: Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma. Breast Cancer Res Treat 88: 75-85, 2004. (Pubitemid 39524447)
36. Mira E, Lacalle RA, Buesa JM, et al: Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface. J Cell Sci 117: 1847-1857, 2004.
37. Shapiro SD: Matrix metalloproteinase degradation of extracellular matrix: biological consequences. Currt Opin Cell Biol 10: 602-608, 1998.
38. Mendes O, Kim HT and Stoica G: Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model. Clin Exp Metastasis 22: 237-246, 2005.
39. Basset P, Bellocq JP, Wolf C, et al: A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature 348: 699-704, 1990. (Pubitemid 120015135)
40. Nakopoulou L, Panayotopoulou EG, Giannopoulou I, et al: Stromelysin-3 protein expression in invasive breast cancer: relation to proliferation, cell survival and patients' outcome. Mod Pathol 15: 1154-1161, 2002. (Pubitemid 35435133)
41. Delany AM and Canalis E: The metastasis-associated metalloproteinase stromelysin-3 is induced by transforming growth factor-beta in osteoblasts and fibroblasts. Endocrinology 142: 1561-1566, 2001. (Pubitemid 32299685)