메뉴 건너뛰기




Volumn 11, Issue 8, 2010, Pages 589-

Missing heritability: Paternal age effect mutations and selfish spermatogonia

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE;

EID: 77954691077     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg2809-c1     Document Type: Letter
Times cited : (32)

References (15)
  • 1
    • 77952557918 scopus 로고    scopus 로고
    • Missing heritability and strategies for finding the underlying causes of complex disease
    • Eichler, E. E. et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nature Rev. Genet. 11, 446-450 (2010).
    • (2010) Nature Rev. Genet. , vol.11 , pp. 446-450
    • Eichler, E.E.1
  • 2
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer, W. & Bonilla, C. Common and rare variants in multifactorial susceptibility to common diseases. Nature Genet. 40, 695-701 (2008).
    • (2008) Nature Genet. , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 3
    • 77952574849 scopus 로고    scopus 로고
    • Uncovering the roles of rare variants in common disease through wholegenome sequencing
    • Cirulli, E. T. & Goldstein D. B. Uncovering the roles of rare variants in common disease through wholegenome sequencing. Nature Rev. Genet. 11, 415-425 (2010).
    • (2010) Nature Rev. Genet. , vol.11 , pp. 415-425
    • Cirulli, E.T.1    Goldstein, D.B.2
  • 4
    • 70350646899 scopus 로고    scopus 로고
    • Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
    • Goriely, A. et al. Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nature Genet. 41, 1247-1252 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 1247-1252
    • Goriely, A.1
  • 5
    • 0042490798 scopus 로고    scopus 로고
    • Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line
    • Goriely, A., McVean, G. A. T., Röjmyr, M., Ingemarsson, B. & Wilkie, A. O. M. Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line. Science 301, 643-646 (2003).
    • (2003) Science , vol.301 , pp. 643-646
    • Goriely, A.1    McVean, G.A.T.2    Röjmyr, M.3    Ingemarsson, B.4    Wilkie, A.O.M.5
  • 6
    • 34548682968 scopus 로고    scopus 로고
    • The molecular anatomy of spontaneous germline mutations in human testes
    • Qin, J. et al. The molecular anatomy of spontaneous germline mutations in human testes. PLoS Biol. 5, e224 (2007).
    • (2007) PLoS Biol. , vol.5
    • Qin, J.1
  • 7
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert, S., Shannon, K. & Bollag, G. Hyperactive Ras in developmental disorders and cancer. Nature Rev. Cancer 7, 295-308 (2007).
    • (2007) Nature Rev. Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 8
    • 58549105755 scopus 로고    scopus 로고
    • MAP'ing CNS development and cognition: An ERKsome process
    • Samuels, I. S., Saitta, S. C. & Landreth, G. E. MAP'ing CNS development and cognition: an ERKsome process. Neuron 61, 160-167 (2009).
    • (2009) Neuron , vol.61 , pp. 160-167
    • Samuels, I.S.1    Saitta, S.C.2    Landreth, G.E.3
  • 9
    • 77954657070 scopus 로고    scopus 로고
    • Functional impact of global rare copy number variation in autism spectrum disorders
    • 9 Jun 2010 doi:10.1038/nature09146
    • Pinto, D. et al. Functional impact of global rare copy number variation in autism spectrum disorders. Nature 9 Jun 2010 (doi:10.1038/nature09146).
    • Nature
    • Pinto, D.1
  • 10
    • 0035189109 scopus 로고    scopus 로고
    • Paternal factors and schizophrenia risk: De novo mutations and imprinting
    • Malaspina, D. Paternal factors and schizophrenia risk: de novo mutations and imprinting. Schizophr. Bull. 3, 379-393 (2001).
    • (2001) Schizophr. Bull. , vol.3 , pp. 379-393
    • Malaspina, D.1
  • 11
    • 72049102124 scopus 로고    scopus 로고
    • Risk of autism and increasing maternal and paternal age in a large North American population
    • Grether, J. K., Anderson, M. C., Croen, L. A., Smith, D. & Windham, G. C. Risk of autism and increasing maternal and paternal age in a large North American population. Am. J. Epidemiol. 170, 1118-1126 (2009).
    • (2009) Am. J. Epidemiol. , vol.170 , pp. 1118-1126
    • Grether, J.K.1    Anderson, M.C.2    Croen, L.A.3    Smith, D.4    Windham, G.C.5
  • 12
    • 37349124883 scopus 로고    scopus 로고
    • Ethnic ancestry and increased paternal age are risk factors for breast cancer before the age of 40 years
    • Weiss-Salz, I. et al. Ethnic ancestry and increased paternal age are risk factors for breast cancer before the age of 40 years. Eur. J. Cancer Prevent. 16, 549-554 (2007).
    • (2007) Eur. J. Cancer Prevent. , vol.16 , pp. 549-554
    • Weiss-Salz, I.1
  • 13
    • 77951799158 scopus 로고    scopus 로고
    • Analysis of genetic inheritance in a family quartet by whole-genome sequencing
    • Roach, J. C. et al. Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science 328, 636-639 (2010).
    • (2010) Science , vol.328 , pp. 636-639
    • Roach, J.C.1
  • 14
    • 0029983638 scopus 로고    scopus 로고
    • Exclusive paternal origin of new mutations in Apert syndrome
    • Moloney, D. M. et al. Exclusive paternal origin of new mutations in Apert syndrome. Nature Genet. 13, 48-53 (1996)
    • (1996) Nature Genet. , vol.13 , pp. 48-53
    • Moloney, D.M.1
  • 15
    • 33749577195 scopus 로고    scopus 로고
    • Age and sex effects on human mutation rates: An old problem with new complexities
    • Crow, J. F. Age and sex effects on human mutation rates: an old problem with new complexities. J. Radiat. Res. 47, B75-B82 (2006).
    • (2006) J. Radiat. Res. , vol.47
    • Crow, J.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.