Intracellular free zinc up-regulates IFN-γ and T-bet essential for Th1 differentiation in Con-A stimulated HUT-78 cells

Biochemical and Biophysical Research Communications

Volumn 407, Issue 4, 2011, Pages 703-707

  Bao, Bin ^a   Prasad, Ananda S ^a   Beck, Frances W J ^a   Bao, Ginny W ^a   Singh, Tapinder ^a   Ali, Shadan ^a   Sarkar, Fazlul H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IFN ; IL 12R 2; T bet; Zinc

Indexed keywords

CHELATING AGENT; CONCANAVALIN A; COPPER; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; IRON; MESSENGER RNA; N,N',N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BIOAVAILABILITY; CELL LEVEL; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FREE ZINC CELL LEVEL; IMMUNOSTIMULATION; INCUBATION TEMPERATURE; INCUBATION TIME; INHIBITION KINETICS; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; TH1 CELL; UPREGULATION; ZINC DEFICIENCY;

CELL DIFFERENTIATION; CELL LINE; CONCANAVALIN A; HUMANS; INTERFERON-GAMMA; RECEPTORS, INTERLEUKIN-12; T-BOX DOMAIN PROTEINS; TH1 CELLS; UP-REGULATION; ZINC;

EID: 79954991358     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.03.084     Document Type: Article

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