Relationship of aldosterone synthase gene (C-344T) and mineralocorticoid receptor (S810L) polymorphisms with gestational hypertension

Journal of Human Hypertension

Volumn 25, Issue 5, 2011, Pages 320-326

  Ramirez Salazar M ^a   Romero Gutierrez G ^b   Zaina, S ^a   Malacara, J M ^a   Kornhauser, C ^a   Perez Luque E ^a  

^a UNIVERSITY OF GUANAJUATO   (Mexico)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

C 344T of CYP11B2 polymorphism; gestational hypertension; S810L mineralocorticoid receptor (MR)

Indexed keywords

ALDOSTERONE SYNTHASE; MINERALOCORTICOID RECEPTOR;

ADULT; ALDOSTERONE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PREGNANCY; PROGESTERONE BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; ALDOSTERONE; ALDOSTERONE SYNTHASE; FEMALE; HUMANS; HYPERTENSION, PREGNANCY-INDUCED; POLYMORPHISM, GENETIC; PREGNANCY; PROGESTERONE; RECEPTORS, MINERALOCORTICOID; RENIN;

EID: 79954848963     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/jhh.2010.58     Document Type: Article

References (32)

1. Roberts JM, Pearson G, Cutler J, Lindheimer M. Summary of the NHLBI Working Group on research on hypertension during pregnancy. Hypertension 2003; 41: 437-445. (Pubitemid 36314613)
2. Pérez-Juárez MP, Castañeda-Sánchez O, Arellano-Cua-dros V, Espinosa-Suárez J. Frecuencia de hipertensión arterial inducida por el embarazo en derechohabientes de una unidad de Medicina Familiar de Cd. Obregón Sonora. Arch Med Familiar 2008; 10: 13-16.
3. Salonen Ros H, Lichtenstein P, Lipworth L, Cnattingius S. Genetic effects on the liability of developing pre-eclampsia and gestational hypertension. Am J Med Genet 2000; 91: 256-260. (Pubitemid 30191247)
4. Chappell S, Morgan L. Searching for genetic clues to the causes of pre-eclampsia. Clin Sci 2006; 110: 443-458.
5. Symonds FM, Broughton-Pipkin F, Craven DJ. Changes in the renin-angiotensin system in primigravidae with hypertensive disease of pregnancy. Br J Obstet Gynae-col 1975; 82: 643-650.
6. Shojaati K, Causevic M, Kedereit B, Dick B, Imobersteg J, Schneider H et al. Evidence for compromised aldo-sterone synthase enzyme activity in preeclampsia. Kidney Int 2004; 66: 2322-2328. (Pubitemid 41115296)
7. Salas SP, Marshall G, Gutiérrez BL, Rosso R. Time course of maternal plasma volume and hormonal changes in women with preeclampsia or fetal growth restriction. Hypertension 2006; 47: 203-208. (Pubitemid 43189764)
8. Oelkers WK. Effects of estrogens and progestogens on the renin-aldosterone system and blood pressure. Steroids 1996; 61: 166-171. (Pubitemid 26146736)
9. Brown MA, Wang J, Whitworth JA. The renin-angiotensin-aldosterone system in pre-eclampsia. Clin Exp Hypertens 1997; 19: 713-726. (Pubitemid 27321699)
10. Tsukada K, Ishimitsu T, Teranishi M, Saitoh M, Yoshil M, Inada H et al. Positive association of CYP11B2 gene polymorphism with genetic predisposition to essential hypertension. J Hum Hypertens 2002; 16: 789-793. (Pubitemid 36007932)
11. Zhu H, Sagnella GA, Dong Y, Miller MA, Onipinla A, Markandu ND et al. Contrasting association between aldosterone synthase gene polymorphisms and essen-tial hypertension in black and in white. J Hypertens 2003; 21: 87-95. (Pubitemid 36143513)
12. Pojoga L, Gautier S, Blanc H, Guyene TT, Poirier O, Cambien F et al. Genetic determination of plasma aldosterone levels in essential hypertension. Am J Hypertens 1998; 11: 856-860. (Pubitemid 28351020)
13. Davies E, Holloway CD, Ingram MC, Inglis GC, Friel EC, Morrison C et al. Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2. Hypertension 1999; 33: 703-707. (Pubitemid 29091652)
14. Lim PO, MacDonald TM, Holloway CH, Friel E, Anderson NH, Dow E et al. Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio. J Clin Endocrinol Metab 2002; 87: 4398-4402.
15. Paillard F, Chansel D, Brand E, Benetos A, Thomas F, Czekalski S et al. Genotype-phenotype relationships for the rennin-angiotensin-aldosterone system in a normal population. Hypertension 1999; 34: 423-429. (Pubitemid 29426758)
16. Barbato A, Russo P, Siani A, Folkerd EJ, Miller MA, Venezia A et al. Aldosterone synthase gene (CYP11B2) C-344T polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic popula-tion. J Hypertens 2004; 22: 1895-1901. (Pubitemid 39336672)
17. Casiglia E, Tikhonoff V, Mazza A, Rynkiewicz A, Limon J, Caffi S et al. C-344T polymorphism of the aldosterone synthase gene and blood pressure in the elderly: a population-based study. J Hypertens 2005; 23:1991-1996. (Pubitemid 41830393)
18. Vasconcelos D, Izidoro-Toledo TC, Sandrim VC, Tanus-Santos JE, Palei A, Cavalli RC. Aldosterone synthase gene polymorphism is not associated with gestational hypertension or preeclampsia. Clinica Chimica Acta 2009; 400: 139-141.
19. Escher G, Cristiano M, Causevic M, Baumann M, Fley FJ, Subek D et al. High aldosterone-to-renin variants of CYP11B2 and pregnancy outcome. Nephrol Dial Transplant 2009; 24: 1870-1875.
20. Percin FE, Cetin M, Pinarbasi E, Akgun E, Gurlek F, Cetin A. Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women. Eur J Obstet Gynecol Reprod Biol 2006; 127: 213-217. (Pubitemid 44189023)
21. Geller DS, Farhi A, Pinkerton N, Fradley M, Moritz M, Spitzer A et al. Activation mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy. Science 2000; 289: 119-123. (Pubitemid 30463305)
22. Schmider-Ross A, Wirsing M, Büscher U, Neitzel H, Krause M, Henrich Wetal. Analysis ofthe S810L point mutation of the mineralocorticoid receptor in patients with pregnancy-induced hypertension. Hypertens Pregnancy 2004; 23: 113-119. (Pubitemid 38445557)
23. Kamide K, Yang J, Kokubo Y, Takiuchi S, Niwa Y, Horio T et al. A novel missense mutation, F826Y, in the mineralocorticoid receptor gene in Japanese hyper-tensives: its implications for clinical phenotypes. Hypertens Res 2005; 28: 703-709. (Pubitemid 41723528)
24. Gifford RW, August PA, Cunningham G, Green LA, Lindheimer MD, McNellis D et al. Report of the national high blood pressure education program work-ing group on the high blood pressure in pregnancy. Am J Obstet Gynecol 2000; 183: S1-S22.
25. Kupari M, Hautanen A, Lankinen L, Koskinen P, Virolainen J, Nikkila H et al. Association between human aldosterone synthase (CYP11B2) gene poly-morphisms and left ventricular size, mass and func-tion. Circulation 1998; 97: 567-575.
26. Portrat-Doyen S, Tourniaire J, Richard O, Mulatero O, Aupetit-Faisant B, Curnow KM et al. Isolated aldoster-one synthase deficiency caused by simultaneous E198D and V386A mutations in the CYP11B2 gene. J Clin Endocrinol Metab 1998; 83: 4156-4161. (Pubitemid 28513610)
27. Myles K, Funder JW. Progesterone binding to miner-alocorticoid receptors: in vitro and in vivo studies. Am J Physiol 1996; 270: F601-F607.
28. Israel A, Peceño A. Renin-angiotensin-aldosterone system in pregnancy-induced hypertension. J Hum Hypertens 2000; 14(Suppl 1): S36-S39. (Pubitemid 30406518)
29. Kim EH, Lim JH, Kim YH, Park YW. The relationship between aldosterone to renin ratio and RI value of the artery in the preeclamptic patient vs normal preg-nancy. Yonsei Med J 2008; 49: 138-143. (Pubitemid 351513656)
30. Miller VM, Vanhoutte PM. Progesterone and modulation of endothelium-dependent responses in canine coronary arteries. Am J Physiol 1991; 261: R1022-R1027.
31. Farese S, Shojaati K, Kadereit B, Frey FJ, Mohaupt MG. Blood pressure reduction in pregnancy by sodium chloride. Nephrol Dial Transplant 2006; 21: 1984-1987. (Pubitemid 43985730)
32. Ballesteros-Vasquez MN, Cabrera-Pacheco RM, Sauce-do-Tamayo MS, Grijalva-Haro MI. Consumo de fibra dietética, sodio, potasio y calcio y su relación con la presión arterial en hombres adultos normotensos. Salud Pública de México 1998; 40: 241-246.