A novel missense mutation, F826Y, in the mineralocorticoid receptor gene in Japanese hypertensives: Its implications for clinical phenotypes

Hypertension Research

Volumn 28, Issue 9, 2005, Pages 703-709

  Kamide, Kei ^a   Yang, Jin ^a   Kokubo, Yoshihiro ^a   Takiuchi, Shin ^a   Miwa, Yoshikazu ^a   Horio, Takeshi ^a   Tanaka, Chihiro ^a   Banno, Mariko ^a   Nagura, Junko ^a   Okayama, Akira ^a   Tomoike, Hitonobu ^a   Kawano, Yuhei ^a   Miyata, Toshiyuki ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Gene variant; Hypertension; Mineralcorticoid receptor; NR3C2

Indexed keywords

ANTIHYPERTENSIVE AGENT; HORMONE BINDING PROTEIN; MINERALOCORTICOID RECEPTOR;

ADULT; AGED; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CARDIOVASCULAR SYMPTOM; CLINICAL FEATURE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; EXON; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENETIC SCREENING; HETEROZYGOTE DETECTION; HORMONE BINDING; HORMONE RECEPTOR INTERACTION; HUMAN; JAPAN; LIGAND BINDING; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN DOMAIN; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE;

AGED; AMINO ACID SEQUENCE; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHENOTYPE; RECEPTORS, MINERALOCORTICOID;

EID: 28444457281     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.28.703     Document Type: Article

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