Hospitalization for severe malnutrition among HIV-infected children starting antiretroviral therapy

AIDS

Volumn 25, Issue 7, 2011, Pages 951-956

  Prendergast, Andrew ^a   Bwakura Dangarembizi, Mutsa F ^b   Cook, Adrian D ^a   Bakeera Kitaka, Sabrina ^c   Natukunda, Eva ^d   Nahirya Ntege, Patricia ^e   Nathoo, Kusum J ^b   Karungi, Christine ^d   Lutaakome, Joseph ^e   Kekitiinwa, Adeodata ^c   Gibb, Diana M ^a  

^a MRC CLINICAL TRIALS UNIT   (United Kingdom)

^b UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^c MULAGO HOSPITAL   (Uganda)

^d JOINT CLINICAL RESEARCH CENTRE   (Uganda)

^e MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Children; HIV; kwashiorkor; malnutrition; marasmus; mortality

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; EFAVIRENZ; LAMIVUDINE; NEVIRAPINE; ZIDOVUDINE;

ADOLESCENT; ARTICLE; CHILD; EDEMA; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; KWASHIORKOR; MAJOR CLINICAL STUDY; MALNUTRITION; MARASMUS; MORTALITY; OUTPATIENT; PRIORITY JOURNAL; UGANDA; ZIMBABWE;

ADOLESCENT; BODY WEIGHT; CD4 LYMPHOCYTE COUNT; CHILD; CHILD, PRESCHOOL; FEMALE; HIV INFECTIONS; HOSPITALIZATION; HUMANS; INFANT; MALE; MALNUTRITION; SEVERITY OF ILLNESS INDEX; UGANDA; ZIMBABWE;

EID: 79954814066     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328345e56b     Document Type: Article

References (16)

1. Koethe JR, Heimburger DC Nutritional aspects of HIV-asso-ciated wasting in sub-Saharan Africa. Am J Clin Nutr 2010; 91:1138S-1142S.
2. Fergusson P, Tomkins A. HIV prevalence and mortality among children undergoing treatment for severe acute mal-nutrition in sub-Saharan Africa: a systematic review and meta-analysis. Trans R Soc Trop Med Hyg 2009; 103:541-548.
3. Puthanakit T, Aurpibul L, Oberdorfer P, Akarathum N, Kanja-nanit S, Wannarit P, et al. Hospitalization and mortality among HIV-infected children after receiving highly active antiretro-viral therapy. Clin Infect Dis 2007; 44:599-604. (Pubitemid 46233267)
4. Sutcliffe CG, van Dijk JH, Bolton C, Persaud D, Moss WJ. Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa. Lancet Infect Dis 2008; 8:477-489. (Pubitemid 352005822)
5. Waterlow JC. Protein-energy malnutrition. London: Edward Arnold; 1992.
6. Amadi B, Kelly P, Mwiya M, Mulwazi E, Sianongo S, Changwe F, et al. Intestinal and systemic infection, HIV, and mortality in Zambian children with persistent diarrhea and malnutrition. J Pediatr Gastroenterol Nutr 2001; 32:550-554. (Pubitemid 32601806)
7. + cell counts. Nutr J 2006; 5:27.
8. Wellcome Working Party. Classification of infantile malnutri-tion. Lancet 1970; 296:302-303.
9. Hughes SM, Amadi B, Mwiya M, Nkamba H, Mulundu G, Tomkins A, Goldblatt D. CD4 counts decline despite nutritional recovery in HIV-infected Zambian children with severe mal-nutrition. Pediatrics 2009; 123:347e-351e.
10. Mori S, Levin P. A brief review of potential mechanisms of immune reconstitution inflammatory syndrome in HIV follow-ing antiretroviral therapy. Int J STD AIDS 2009; 20:447-452.
11. Mahanna HM, MoledinaJ, TravisJ. Refeedingsyndrome:what it is, and how to prevent and treat it. BMJ 2008; 336:1495 1498. (Pubitemid 351977023)
12. Sauvageot D, Schaefer M, Olson D, Pujades-Rodriguez M, O'Brien DP. Antiretroviral therapy outcomes in resource-limited settings for HIV-infected children <5 years of age. Pediatrics 2010; 125:e1039-e1047
13. Lucas GM, Chaisson RE, Moore RD. Highly active antiretro-viral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions. Ann Intern Med 1999; 131:81-87. (Pubitemid 29340558)
14. World Health Organization. Guidelines for an integrated approach to the nutritional care of HIV-infected children (6 months-14 years). Geneva: WHO Press; 2009. http://www.who.int/nutrition/publications/hivaids/9789241597524/en/ index.html. [Accessed21 January2011]
15. Heikens GT, Bunn J, Amadi B, Manary M, Chhagan M, Berkley JA, et al. Case management of HIV-infected severely malnour-ished children: challenges in the area of highest prevalence. Lancet 2008; 371:1305-1307. (Pubitemid 351491320)
16. World Health Organization. Antiretroviral therapy for HIV infection in infants and children: towards universal access. Recommendations for a public health approach. Geneva: WHO Press; 2010. http://www.who.int/hiv/pub/guidelines/ art/en/. [Accessed 24th January 2011]