Refeeding syndrome: What it is, and how to prevent and treat it

BMJ

Volumn 336, Issue 7659, 2008, Pages 1495-1498

  Mehanna, Hisham M ^a,b   Moledina, Jamil ^c   Travis, Jane ^c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY HOSPITAL COVENTRY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM SALT; ANTACID AGENT; CALCIUM; DIURETIC AGENT; GLUCOSE; MAGNESIUM; MAGNESIUM SALT; MINERAL; NITROGEN; PHOSPHATE; PHOSPHORUS; POTASSIUM; SODIUM; THIAMINE; TRACE ELEMENT; VITAMIN B GROUP;

ARTIFICIAL FEEDING; CLINICAL FEATURE; DISEASE COURSE; DISEASE PREDISPOSITION; ELECTROLYTE BLOOD LEVEL; ELECTROLYTE DISTURBANCE; GLUCOSE BLOOD LEVEL; HIGH RISK POPULATION; HUMAN; HYPERGLYCEMIA; HYPOPHOSPHATEMIA; INCIDENCE; MALNUTRITION; MEDICAL PRACTICE; MINERAL BLOOD LEVEL; NUTRITIONAL SUPPORT; PRACTICE GUIDELINE; PRIORITY JOURNAL; REFEEDING SYNDROME; REVIEW; RISK FACTOR; VITAMIN DEFICIENCY; VITAMIN SUPPLEMENTATION;

FASTING; HUMANS; MALNUTRITION; NUTRITIONAL SUPPORT; PRACTICE GUIDELINES AS TOPIC; SYNDROME; WATER-ELECTROLYTE IMBALANCE;

EID: 47149113422     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.a301     Document Type: Review

References (20)

1. Hearing SD. Refeeding syndrome. BMJ 2004;328:908-9.
2. Evidence-Based On-Call Database. Levels of evidence. 2007. www.eboncall.org/content/levels.html
3. National Institute for Health and Clinical Excellence. Nutrition support in adults. Clinical guideline CG32. 2006. www.nice.org.uk/page.aspx? o=cg032
4. Dewar H, Horvath R. Refeeding syndrome. In: Todorovic VE, Micklewright A, eds. A pocket guide to clinical nutrition. 2nd ed. British Dietetic Association, 2001.
5. Solomon SM, Kirby DF. The refeeding syndrome: a review. JPEN J Parenter Enteral Nutr 1990;14:90-7.
6. Crook MA, Hally V, Pantelli JV. The importance of the refeeding syndrome. Nutrition 2001;17:632-7.
7. Camp MA, Allon M. Severe hypophosphatemia in hospitalised patients. Mineral & Electrolyte Metabolism 1990;16:365-8.
8. Martinez MJ, Matrinez MA, Montero M, Campelo E, Castro I, Inaraja MT. Hypophosphatemia in postoperative patients on total parenteral nutritiom:influence of nutritional support teams. Nutr Hosp 2006;21:657-60.
9. Hayek ME, Eisenberg PG. Severe hypophosphatemia following the institution of enteral feedings. Arch Surg 1989;124:1325-8.
10. Marik PE, Bedigan MK. Refeeding hypophosphataemia in an intensive care unit: a prospective study. Arch Surg 1996;131:1043-7.
11. Silvis SE, Paragas PD. Parasthesias, weakness, seizures, and hypophosphatemia in patients receiving hyperalimentation. Gastroenterology 1972;62:513-20.
12. Weinsier RL, Krumdieck CL. Death resulting from overzealous total parenteral nutrition: the refeeding syndrome revisited. Am J Clin Nutr 1980;34:393-9.
13. McCray S, Walker S, Parrish CR. Much ado about refeeding. Practical Gastroenterology 2004;XXVIII(12):26-44.
14. Knochel JP. The pathophysiology and clinical charactertistics of severe hypophosphatemia. Arch Intern Med 1977;137:203-20.
15. Klein CJ, Stanek GS, Wiles CE. Overfeeding macronutrients to critically ill adults: metabolic complications. J Am Diet Assoc 1998;98:795-806.
16. Perrault MM, Ostrop NJ, Tiemey MG. Efficacy and safety of intravenous phosphate replacement in critically ill patients. Ann Pharmacother 1997;31:683-8.
17. Terlevich A, Hearing SD, Woltersdorf WW, Smyth C, Reid D, Mccullagh E, et al. Refeeding syndrome: effective and safe treatment with Phosphates Polyfusor. Aliment Pharmacol Ther 2003;17:1325-9.
18. Wacker WEC, Parisi AF. Magnesium metabolism. N Engl J Med 1968;278:658-63.
19. Reuler JB, Girard DE, Cooney TG. Wernicke's encephalopathy. N Engl J Med 1985;312:1035-9.
20. Veverbrants E, Arky RA. Effects of fasting and refeeding: I. Studies on sodium, potassium and water excretion on a constant electrolyte and fluid intake. J Clin Endocrinol Metab 1969;29:55-62.