Enhancement of drug efflux activity via MDR1 protein by spheroid culture of human hepatic cancer cells

Journal of Bioscience and Bioengineering

Volumn 111, Issue 5, 2011, Pages 590-593

  Oshikata, Ayumi ^a   Matsushita, Taku ^a   Ueoka, Ryuichi ^a  

^a SOJO UNIVERSITY   (Japan)

Author keywords

Cell based assay system; Doxorubicin; Hepatic cancer cells; IC50; MDR1; Multidrug resistance; Spheroid

Indexed keywords

CELL-BASED ASSAYS; DOXORUBICIN; HEPATIC CANCER CELLS; IC50; MDR1; MULTIDRUG RESISTANCE; SPHEROID;

AMINO ACIDS; CELL CULTURE; DISEASES; MONOLAYERS; ORGANIC ACIDS; PROTEINS; TISSUE;

CELLS;

DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; MULTIDRUG RESISTANCE PROTEIN 1;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RESISTANCE; CELL ACTIVITY; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG TRANSPORT; HUMAN; HUMAN CELL; IC 50; LIVER CANCER; MONOLAYER CULTURE; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; SPHEROID CELL; WESTERN BLOTTING;

CELL CULTURE TECHNIQUES; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EPIRUBICIN; FLUOROURACIL; GLUTAMIC ACID; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; P-GLYCOPROTEIN; SPHEROIDS, CELLULAR;

EID: 79954752177     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2011.01.006     Document Type: Article

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