-
1
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
DOI 10.1126/science.1079490
-
S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061 (Pubitemid 36222930)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
2
-
-
0346969978
-
- T cells
-
DOI 10.1172/JCI200319441
-
M.R. Walker, D.J. Kasprowicz, V.H. Gersuk, A. Benard, M. Van Landeghen, and J.H. Buckner Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells J Clin Invest 112 2003 1437 1443 (Pubitemid 38057697)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.9
, pp. 1437-1443
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
Benard, A.4
Van Landeghen, M.5
Buckner, J.H.6
Ziegler, S.F.7
-
3
-
-
33947121146
-
Transient regulatory T-cells: A state attained by all activated human T-cells
-
DOI 10.1016/j.clim.2006.10.014, PII S1521661606009405
-
V. Pillai, S.B. Ortega, C.K. Wang, and N.J. Karandikar Transient regulatory T-cells: a state attained by all activated human T-cells Clin Immunol 123 2007 18 29 (Pubitemid 46401504)
-
(2007)
Clinical Immunology
, vol.123
, Issue.1
, pp. 18-29
-
-
Pillai, V.1
Ortega, S.B.2
Wang, C.K.3
Karandikar, N.J.4
-
4
-
-
33646251141
-
Transforming growth factor beta induced FoxP3+ regulatory T cells suppress Th1 mediated experimental colitis
-
M.C. Fantini, C. Becker, I. Tubbe, A. Nikolaev, H.A. Lehr, and P. Galle Transforming growth factor beta induced FoxP3+ regulatory T cells suppress Th1 mediated experimental colitis Gut 55 2006 671 680
-
(2006)
Gut
, vol.55
, pp. 671-680
-
-
Fantini, M.C.1
Becker, C.2
Tubbe, I.3
Nikolaev, A.4
Lehr, H.A.5
Galle, P.6
-
5
-
-
1242267910
-
+ Regulatory T Cells Generated Ex Vivo with IL-2 and TGF-β Suppress a Stimulatory Graft-versus-Host Disease with a Lupus-Like Syndrome
-
S.G. Zheng, J.H. Wang, M.N. Koss, F. Quismorio Jr., J.D. Gray, and D.A. Horwitz CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome J Immunol 172 2004 1531 1539 (Pubitemid 38116797)
-
(2004)
Journal of Immunology
, vol.172
, Issue.3
, pp. 1531-1539
-
-
Zheng, S.G.1
Wang, J.H.2
Koss, M.N.3
Quismorio Jr., F.4
Gray, J.D.5
Horwitz, D.A.6
-
6
-
-
63549097293
-
In vitro induced CD4(+)CD25(+)Foxp3(+) Tregs attenuate hepatic ischemia-reperfusion injury
-
L. Lu, G. Li, J. Rao, L. Pu, Y. Yu, and X. Wang In vitro induced CD4(+)CD25(+)Foxp3(+) Tregs attenuate hepatic ischemia-reperfusion injury Int Immunopharmacol 9 2009 549 552
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 549-552
-
-
Lu, L.1
Li, G.2
Rao, J.3
Pu, L.4
Yu, Y.5
Wang, X.6
-
7
-
-
35448930435
-
- T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
-
DOI 10.1182/blood-2007-06-094656
-
D.Q. Tran, H. Ramsey, and E.M. Shevach Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype Blood 110 2007 2983 2990 (Pubitemid 350006952)
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2983-2990
-
-
Tran, D.Q.1
Ramsey, H.2
Shevach, E.M.3
-
8
-
-
33745633856
-
+ regulatory T-cell function by calcineurin-dependent interleukin-2 production
-
DOI 10.1182/blood-2006-01-0329
-
R. Zeiser, V.H. Nguyen, A. Beilhack, M. Buess, S. Schulz, and J. Baker Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production Blood 108 2006 390 399 (Pubitemid 43990654)
-
(2006)
Blood
, vol.108
, Issue.1
, pp. 390-399
-
-
Zeiser, R.1
Nguyen, V.H.2
Beilhack, A.3
Buess, M.4
Schulz, S.5
Baker, J.6
Contag, C.H.7
Negrin, R.S.8
-
9
-
-
77953674618
-
Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation
-
L. Lu, X.F. Qian, J.H. Rao, X.H. Wang, and F. SG, Zhang Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation Transplant Proc 42 2010 1755 1757
-
(2010)
Transplant Proc
, vol.42
, pp. 1755-1757
-
-
Lu, L.1
Qian, X.F.2
Rao, J.H.3
Wang, X.H.4
Zhang F, S.G.5
-
10
-
-
34250156673
-
Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells
-
DOI 10.1111/j.1600-6143.2007.01842.x
-
W. Gao, Y. Lu, B. El Essawy, M. Oukka, V.K. Kuchroo, and T.B. Strom Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells Am J Transplant 7 2007 1722 1732 (Pubitemid 46905432)
-
(2007)
American Journal of Transplantation
, vol.7
, Issue.7
, pp. 1722-1732
-
-
Gao, W.1
Lu, Y.2
El Essawy, B.3
Oukka, M.4
Kuchroo, V.K.5
Strom, T.B.6
-
11
-
-
0034667761
-
Rapamycin induces transforming growth factor-beta production by lymphocytes
-
I.L. Dodge, G. Demirci, T.B. Strom, and X.C. Li Rapamycin induces transforming growth factor-beta production by lymphocytes Transplantation 70 2000 1104 1106
-
(2000)
Transplantation
, vol.70
, pp. 1104-1106
-
-
Dodge, I.L.1
Demirci, G.2
Strom, T.B.3
Li, X.C.4
-
12
-
-
33745861719
-
+ T cells
-
D. Valmori, V. Tosello, N.E. Souleimanian, E. Godefroy, L. Scotto, and Y. Wang Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells J Immunol 177 2006 944 949 (Pubitemid 44036595)
-
(2006)
Journal of Immunology
, vol.177
, Issue.2
, pp. 944-949
-
-
Valmori, D.1
Tosello, V.2
Souleimanian, N.E.3
Godefroy, E.4
Scotto, L.5
Wang, Y.6
Ayyoub, M.7
-
13
-
-
74249121391
-
Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg
-
L. Lu, J. Ma, X. Wang, J. Wang, F. Zhang, and J. Yu Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg Eur J Immunol 40 2010 142 152
-
(2010)
Eur J Immunol
, vol.40
, pp. 142-152
-
-
Lu, L.1
Ma, J.2
Wang, X.3
Wang, J.4
Zhang, F.5
Yu, J.6
-
14
-
-
77952777819
-
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells
-
L. Lu, J. Wang, F. Zhang, Y. Chai, D. Brand, and X. Wang Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells J Immunol 184 2010 4295 4306
-
(2010)
J Immunol
, vol.184
, pp. 4295-4306
-
-
Lu, L.1
Wang, J.2
Zhang, F.3
Chai, Y.4
Brand, D.5
Wang, X.6
-
15
-
-
1242290580
-
- Cells to Develop Suppressive Activity: The Role of IL-2, TGF-β, and IL-10
-
S.G. Zheng, J.H. Wang, J.D. Gray, H. Soucier, and D.A. Horwitz Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10 J Immunol 172 2004 5213 5221 (Pubitemid 38542018)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5213-5221
-
-
Zheng, S.G.1
Wang, J.H.2
Gray, J.D.3
Soucier, H.4
Horwitz, D.A.5
-
16
-
-
67650105331
-
Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin
-
L. Strauss, M. Czystowska, M. Szajnik, M. Mandapathil, and T.L. Whiteside Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin PLoS ONE 4 2009 e5994
-
(2009)
PLoS ONE
, vol.4
, pp. 5994
-
-
Strauss, L.1
Czystowska, M.2
Szajnik, M.3
Mandapathil, M.4
Whiteside, T.L.5
-
17
-
-
0037108485
-
- precursors
-
S.G. Zheng, J.D. Gray, K. Ohtsuka, S. Yamagiwa, and D.A. Horwitz Generation ex vivo of TGF-beta-producing regulatory T cells from CD4 + CD25- precursors J Immunol 169 2002 4183 4189 (Pubitemid 35178188)
-
(2002)
Journal of Immunology
, vol.169
, Issue.8
, pp. 4183-4189
-
-
Zheng, S.G.1
Gray, J.D.2
Ohtsuka, K.3
Yamagiwa, S.4
Horwitz, D.A.5
-
18
-
-
32844466881
-
Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells
-
DOI 10.1097/01.tp.0000194860.21533.b9
-
N. Nikolaeva, F.J. Bemelman, S.L. Yong, R.A. van Lier, and I.J. ten Berge Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells Transplantation 81 2006 445 454 (Pubitemid 43255733)
-
(2006)
Transplantation
, vol.81
, Issue.3
, pp. 445-454
-
-
Nikolaeva, N.1
Bemelman, F.J.2
Yong, S.-L.3
Van Lier, R.A.W.4
Ten Berge, I.J.M.5
-
19
-
-
20444373376
-
+ regulatory T cells
-
DOI 10.1182/blood-2004-10-3932
-
M. Battaglia, A. Stabilini, and M.G. Roncarolo Rapamycin selectively expands CD4 + CD25 + FoxP3+ regulatory T cells Blood 105 2005 4743 4748 (Pubitemid 40807298)
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.-G.3
-
20
-
-
0141481990
-
-/- double-mutant mice
-
DOI 10.1182/blood-2002-10-3241
-
R.S. van Rijn, E.R. Simonetti, A. Hagenbeek, M.C. Hogenes, R.A. de Weger, and M.R. Canninga-van Dijk A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice Blood 102 2003 2522 2531 (Pubitemid 37193591)
-
(2003)
Blood
, vol.102
, Issue.7
, pp. 2522-2531
-
-
Van Rijn, R.S.1
Simonetti, E.R.2
Hagenbeek, A.3
Hogenes, M.C.H.4
De Weger, R.A.5
Canninga-Van Dijk, M.R.6
Weijer, K.7
Spits, H.8
Storm, G.9
Van Bloois, L.10
Rijkers, G.11
Martens, A.C.M.12
Ebeling, S.B.13
-
21
-
-
33749361494
-
-/- immunodeficient mice
-
DOI 10.1158/1078-0432.CCR-06-0035
-
T. Mutis, R.S. van Rijn, E.R. Simonetti, T. Aarts-Riemens, M.E. Emmelot, and L. van Bloois Human regulatory T cells control xenogeneic graft-versus-host disease induced by autologous T cells in RAG2-/-gammac-/- immunodeficient mice Clin Cancer Res 12 2006 5520 5525 (Pubitemid 44497269)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.18
, pp. 5520-5525
-
-
Mutis, T.1
Van Rijn, R.S.2
Simonetti, E.R.3
Aarts-Riemens, T.4
Emmelot, M.E.5
Van Bloois, L.6
Martens, A.7
Verdonck, L.F.8
Ebeling, S.B.9
-
22
-
-
0032105481
-
Rapamune® (RAPA, rapamycin, sirolimus): Mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
-
DOI 10.1016/S0009-9120(98)00045-9, PII S0009912098000459
-
S.N. Sehgal Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression Clin Biochem 31 1998 335 340 (Pubitemid 28385231)
-
(1998)
Clinical Biochemistry
, vol.31
, Issue.5
, pp. 335-340
-
-
Sehgal, S.N.1
-
23
-
-
34247387873
-
+ T cells
-
DOI 10.1038/sj.bmt.1705628, PII 1705628
-
J.J. Coenen, H.J. Koenen, E. van Rijssen, A. Kasran, L. Boon, and L.B. Hilbrands Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells Bone Marrow Transplant 39 2007 537 545 (Pubitemid 46629589)
-
(2007)
Bone Marrow Transplantation
, vol.39
, Issue.9
, pp. 537-545
-
-
Coenen, J.J.A.1
Koenen, H.J.P.M.2
Van Rijssen, E.3
Kasran, A.4
Boon, L.5
Hilbrands, L.B.6
Joosten, I.7
-
24
-
-
1642577126
-
+ Regulatory T Cell Activity in Both Humans and Mice
-
K. Nakamura, A. Kitani, I. Fuss, A. Pedersen, N. Harada, and H. Nawata TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice J Immunol 172 2004 834 842 (Pubitemid 38113739)
-
(2004)
Journal of Immunology
, vol.172
, Issue.2
, pp. 834-842
-
-
Nakamura, K.1
Kitani, A.2
Fuss, I.3
Pedersen, A.4
Harada, N.5
Nawata, H.6
Strober, W.7
-
25
-
-
0035801335
-
+ regulatory T cells is mediated by cell surface-bound transforming growth factor β
-
DOI 10.1084/jem.194.5.629
-
K. Nakamura, A. Kitani, and W. Strober Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta J Exp Med 194 2001 629 644 (Pubitemid 32844773)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.5
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
26
-
-
0034844841
-
Oral tolerance: Immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells
-
DOI 10.1016/S1286-4579(01)01456-3
-
H.L. Weiner Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells Microbes Infect 3 2001 947 954 (Pubitemid 32835309)
-
(2001)
Microbes and Infection
, vol.3
, Issue.11
, pp. 947-954
-
-
Weiner, H.L.1
-
27
-
-
53749106117
-
Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells
-
R.G. Carroll, C. Carpenito, X. Shan, G. Danet-Desnoyers, R. Liu, and S. Jiang Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells PLoS ONE 3 2008 e3289
-
(2008)
PLoS ONE
, vol.3
, pp. 3289
-
-
Carroll, R.G.1
Carpenito, C.2
Shan, X.3
Danet-Desnoyers, G.4
Liu, R.5
Jiang, S.6
-
28
-
-
53449091065
-
Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells
-
K.L. Hippen, P. Harker-Murray, S.B. Porter, S.C. Merkel, A. Londer, and D.K. Taylor Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells Blood 112 2008 2847 2857
-
(2008)
Blood
, vol.112
, pp. 2847-2857
-
-
Hippen, K.L.1
Harker-Murray, P.2
Porter, S.B.3
Merkel, S.C.4
Londer, A.5
Taylor, D.K.6
-
29
-
-
67649580473
-
Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
-
R. Ito, I. Katano, K. Kawai, H. Hirata, T. Ogura, and T. Kamisako Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice Transplantation 87 2009 1654 1658
-
(2009)
Transplantation
, vol.87
, pp. 1654-1658
-
-
Ito, R.1
Katano, I.2
Kawai, K.3
Hirata, H.4
Ogura, T.5
Kamisako, T.6
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