HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection

Analytical and Bioanalytical Chemistry

Volumn 400, Issue 2, 2011, Pages 387-393

  Wada, Mitsuhiro ^a   Abe, Keisuke ^a   Ikeda, Rie ^a   Kikura Hanajiri, Ruri ^b   Kuroda, Naotaka ^a   Nakashima, Kenichiro ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

4 (N,N dimethylaminosulfonyl) 7 fluoro 2,1,3 benzoxadiazole; HPLC; Methylphenidate; Peroxyoxalate chemiluminescence; Ritalinic acid

Indexed keywords

4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE; HPLC; METHYLPHENIDATE; PEROXYOXALATE-CHEMILUMINESCENCE; RITALINIC ACID;

CHEMILUMINESCENCE; CHROMATOGRAPHY; EXTRACTION; SIGNAL TO NOISE RATIO;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CENTRAL STIMULANT AGENT; DRUG DERIVATIVE; METHYLPHENIDATE; OXALIC ACID DERIVATIVE; PEROXYOXALIC ACID; RITALINIC ACID;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; CHEMOLUMINESCENCE; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; MALE; METABOLISM; METHODOLOGY; RAT; WISTAR RAT;

ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; CHEMILUMINESCENT MEASUREMENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; METHYLPHENIDATE; OXALATES; RATS; RATS, WISTAR;

RATTUS;

EID: 79954629316     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-4713-0     Document Type: Article

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