A method for measuring the lipophilicity of compounds in mixtures of 10

Journal of Biomolecular Screening

Volumn 16, Issue 3, 2011, Pages 348-355

  Wenlock, Mark C ^a   Potter, Tim ^a   Barton, Patrick ^a   Austin, Rupert P ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

high throughput screening; ion pair partitioning; LC MS; lipophilicity; physiochemical properties

Indexed keywords

ALBENDAZOLE; AMIODARONE; ATENOLOL; BUMETANIDE; CAFFEINE; CHLORPROMAZINE; CHLORTALIDONE; CLONIDINE; CYCLOBENZAPRINE; DIPHENYLAMINE; ENALAPRIL; ESTRADIOL; FLUCONAZOLE; GLIBENCLAMIDE; INDOMETACIN; LORATADINE; OCTANOL; PENTOXIFYLLINE; PROCAINAMIDE; PROPRANOLOL; SILICON; TOLBUTAMIDE; TOLNAFTATE; TRAZODONE; WATER;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION PAIR CHROMATOGRAPHY; LIPOPHILICITY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

BIOLOGICAL ASSAY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; LIPID METABOLISM; LIPIDS; REPRODUCIBILITY OF RESULTS; SOLUBILITY;

EID: 79954616098     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110396372     Document Type: Article

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