Genistein alters caffeine exposure in healthy female volunteers

European Journal of Clinical Pharmacology

Volumn 67, Issue 4, 2011, Pages 347-353

  Chen, Yao ^a   Xiao, Chang Qiong ^a   He, Yi Jing ^a   Chen, Bi Lian ^a   Wang, Guo ^a   Zhou, Gan ^a   Zhang, Wei ^a   Tan, Zhi Rong ^a   Cao, Shan ^a   Wang, Li Ping ^a   Zhou, Hong Hao ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

CYP1A2; CYP2A6; Genistein; NAT2; XO

Indexed keywords

1 METHYLURATE; 1 METHYLXANTHINE; 1,7 DIMETHYLURATE; 5 ACETAMIDO 6 FORMYLAMINO 3 METHYLURACIL; ARYLAMINE ACETYLTRANSFERASE; CAFFEINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; GENISTEIN; PARAXANTHINE; UNCLASSIFIED DRUG; URATE; XANTHINE OXIDASE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG METABOLISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MAXIMUM PLASMA CONCENTRATION; METABOLITE; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE STUDY; TIME TO MAXIMUM PLASMA CONCENTRATION; URINALYSIS;

ADOLESCENT; ADULT; ARYL HYDROCARBON HYDROXYLASES; ARYLAMINE N-ACETYLTRANSFERASE; CAFFEINE; CYTOCHROME P-450 CYP1A2; DRUG INTERACTIONS; FEMALE; GENISTEIN; HUMANS; XANTHINE OXIDASE;

EID: 79954615110     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0964-5     Document Type: Article

References (23)

1. ZH Liu Y Kanjo S Mizutani 2010 A review of phytoestrogens: their occurrence and fate in the environment Water Res 44 567 577 19375769 10.1016/j.watres.2009.03.025 1:CAS:528:DC%2BC3cXhvFegs7g%3D
2. P Villa B Costantini R Suriano, et al. 2009 The differential effect of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women: relationship with the metabolic status J Clin Endocrinol Metab 94 552 558 19017760 10.1210/jc.2008-0735 1:CAS:528:DC%2BD1MXhvFCqtr4%3D
3. LM Scott P Durant S Leone-Kabler, et al. 2008 Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes J Steroid Biochem Mol Biol 112 179 185 18955142 10.1016/j.jsbmb.2008. 10.001 1:CAS:528:DC%2BD1cXhsFamtLnP
4. YH Shon SD Park KS Nam 2006 Effective chemopreventive activity of genistein against human breast cancer cells J Biochem Mol Biol 39 448 451 16889690 1:CAS:528:DC%2BD28XotlygsLs%3D
5. NA Helsby JK Chipman A Gescher, et al. 1998 Inhibition of mouse and human CYP 1A- and 2E1-dependent substrate metabolism by the isoflavonoids genistein and equol Food Chem Toxicol 36 375 382 9662412 10.1016/S0278-6915(97)00171-3 1:CAS:528:DyaK1cXktVCktr8%3D (Pubitemid 28267366)
6. X Li JS Choi 2007 Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats Int J Pharm 337 188 193 17267149 10.1016/j.ijpharm.2007.01.002 1:CAS:528:DC%2BD2sXlsFagsr0%3D (Pubitemid 46756050)
7. MG Myers 1991 Caffeine and cardiac arrhythmias Ann Intern Med 114 147 150 1984393 1:STN:280:DyaK3M%2Fns1erug%3D%3D
8. MC Cornelis A El-Sohemy 2007 Coffee, caffeine, and coronary heart disease Curr Opin Clin Nutr Metab Care 10 745 751 18089957 10.1097/MCO.0b013e3282f05d81 1:CAS:528:DC%2BD2sXhtlGgu7rK (Pubitemid 350293776)
9. SS Tworoger DM Gertig MA Gates, et al. 2008 Caffeine, alcohol, smoking, and the risk of incident epithelial ovarian cancer Cancer 112 1169 1177 18213613 10.1002/cncr.23275 (Pubitemid 351304604)
10. MS Caubet W Elbast MC Dubuc, et al. 2002 Analysis of urinary caffeine metabolites by HPLC-DAD: the use of metabolic ratios to assess CYP1A2 enzyme activity J Pharm Biomed Anal 27 261 270 11682234 10.1016/S0731-7085(01)00546-5 1:CAS:528:DC%2BD3MXnslWqtLs%3D (Pubitemid 33001404)
11. A Rostami-Hodjegan S Nurminen PR Jackson, et al. 1996 Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment Pharmacogenetics 6 121 149 9156692 10.1097/00008571-199604000-00001 1:CAS:528:DyaK28XjsVeqsro%3D (Pubitemid 26153358)
12. BK Tang Y Zhou D Kadar, et al. 1994 Caffeine as a probe for CYP1A2 activity: potential influence of renal factors on urinary phenotypic trait measurements Pharmacogenetics 4 117 124 7920691 10.1097/00008571-199406000-00002 1:CAS:528:DyaK2MXmsFemtA%3D%3D (Pubitemid 24210929)
13. BK Tang D Kadar L Qian, et al. 1991 Caffeine as a metabolic probe: validation of its use for acetylator phenotyping Clin Pharmacol Ther 49 648 657 2060254 10.1038/clpt.1991.82 1:CAS:528:DyaK3MXkvVCkurs%3D
14. W Kalow BK Tang 1991 Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities Clin Pharmacol Ther 50 508 519 1934864 10.1038/clpt.1991.176 1:CAS:528:DyaK38XhslGhug%3D%3D
15. P Wong G Villeneuve V Tessier, et al. 2002 Stability of 5-acetamido-6-formylamino-3-methyluracil in buffers and urine J Pharmaceut Biomed 28 693 700 10.1016/S0731-7085(01)00656-2 1:CAS:528:DC%2BD38Xjtl2gu7g%3D (Pubitemid 34465635)
16. DM Grant BK Tang W Kalow 1983 Variability in caffeine metabolism Clin Pharmacol Ther 33 591 602 6687705 10.1038/clpt.1983.80 1:CAS:528: DyaL3sXkt1Whu70%3D (Pubitemid 13098529)
17. MA Butler NP Lang JF Young, et al. 1992 Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites Pharmacogenetics 2 116 127 1306111 10.1097/00008571-199206000-00003 1:CAS:528:DyaK3sXlsFWlsr0%3D
18. W Tassaneeyakul DJ Birkett ME Veronese, et al. 1993 Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2 J Pharmacol Exp Ther 265 401 407 8474022 1:CAS:528:DyaK3sXkt1ens7w%3D (Pubitemid 23320988)
19. ES Messina RF Tyndale EM Sellers 1997 A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes J Pharmacol Exp Ther 282 1608 1614 9316878 1:CAS:528:DyaK2sXmsVGlu7s%3D (Pubitemid 27408347)
20. KI Nunoya T Yokoi K Kimura, et al. 1999 A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3, 5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans J Pharmacol Exp Ther 289 437 442 10087035 1:CAS:528:DyaK1MXit1Khtb4%3D (Pubitemid 29156060)
21. S Nowell C Sweeney G Hammons, et al. 2002 CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk Cancer Epidemiol Biomarkers Prev 11 377 383 11927498 1:CAS:528:DC%2BD38XjtlCmtrg%3D (Pubitemid 34408217)
22. JF Hsieh SH Wu YL Yang, et al. 2007 The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors Bioorg Med Chem 15 3450 3456 17379526 10.1016/j.bmc.2007.03.010 1:CAS:528:DC%2BD2sXjvFOlsr4%3D (Pubitemid 46529261)
23. AA Fatokun TW Stone RA Smith 2007 Hydrogen peroxide mediates damage by xanthine and xanthine oxidase in cerebellar granule neuronal cultures Neurosci Lett 416 34 38 17360118 10.1016/j.neulet.2007.01.078 1:CAS:528: DC%2BD2sXjsVeku78%3D (Pubitemid 46428008)