-
1
-
-
67650732783
-
Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders
-
K. Ahn, D.S. Johnson, and B.F. Cravatt Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders Expert Opin Drug Discov 4 2009 763 784
-
(2009)
Expert Opin Drug Discov
, vol.4
, pp. 763-784
-
-
Ahn, K.1
Johnson, D.S.2
Cravatt, B.F.3
-
2
-
-
44849141696
-
Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
-
DOI 10.1021/cr0782067
-
K. Ahn, M.K. McKinney, and B.F. Cravatt Enzymatic pathways that regulate endocannabinoid signaling in the nervous system Chem Rev 108 2008 1687 1707 (Pubitemid 351796405)
-
(2008)
Chemical Reviews
, vol.108
, Issue.5
, pp. 1687-1707
-
-
Ahn, K.1
McKinney, M.K.2
Cravatt, B.F.3
-
3
-
-
0029904838
-
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
-
DOI 10.1038/384083a0
-
B.F. Cravatt, D.K. Giang, S.P. Mayfield, D.L. Boger, R.A. Lerner, and N.B. Gilula Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides Nature 384 1996 83 87 (Pubitemid 26374593)
-
(1996)
Nature
, vol.384
, Issue.6604
, pp. 83-87
-
-
Cravatt, B.F.1
Giang, D.K.2
Mayfield, S.P.3
Boger, D.L.4
Lerner, R.A.5
Gilula, N.B.6
-
4
-
-
29444460231
-
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
-
DOI 10.1073/pnas.0509591102
-
G. Gobbi, F.R. Bambico, R. Mangieri, M. Bortolato, P. Campolongo, M. Solinas, T. Cassano, M.G. Morgese, G. Debonnel, A. Duranti, A. Tontini, G. Tarzia, M. Mor, V. Trezza, S.R. Goldberg, V. Cuomo, and D. Piomelli Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis Proc Natl Acad Sci USA 102 2005 18620 18625 (Pubitemid 43011275)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.51
, pp. 18620-18625
-
-
Gobbi, G.1
Bambico, F.R.2
Mangieri, R.3
Bortolato, M.4
Campolongo, P.5
Solinas, M.6
Cassano, T.7
Morgese, M.G.8
Debonnel, G.9
Duranti, A.10
Tontini, A.11
Tarzia, G.12
Mor, M.13
Trezza, V.14
Goldberg, S.R.15
Cuomo, V.16
Piomelli, D.17
-
5
-
-
0037234363
-
Modulation of anxiety through blockade of anandamide hydrolysis
-
DOI 10.1038/nm803
-
S. Kathuria, S. Gaetani, D. Fegley, F. Valino, A. Duranti, A. Tontini, M. Mor, G. Tarzia, G.L. Rana, A. Calignano, A. Giustino, M. Tattoli, M. Palmery, V. Cuomo, and D. Piomelli Modulation of anxiety through blockade of anandamide hydrolysis Nat Med 9 2003 76 81 (Pubitemid 36098263)
-
(2003)
Nature Medicine
, vol.9
, Issue.1
, pp. 76-81
-
-
Kathuria, S.1
Gaetani, S.2
Fegley, D.3
Valino, F.4
Duranti, A.5
Tontini, A.6
Mor, M.7
Tarzia, G.8
La Rana, G.9
Calignano, A.10
Giustino, A.11
Tattoli, M.12
Palmery, M.13
Cuomo, V.14
Piomelli, D.15
-
6
-
-
4644354869
-
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity
-
DOI 10.1124/jpet.104.069401
-
A.H. Lichtman, D. Leung, C. Shelton, A. Saghatelian, C. Hardouin, D. Boger, and B.F. Cravatt Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity J Pharmacol Exp Ther 311 2004 441 448 (Pubitemid 39391527)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.311
, Issue.2
, pp. 441-448
-
-
Lichtman, A.H.1
Leung, D.2
Shelton, C.C.3
Saghatelian, A.4
Hardouin, C.5
Boger, D.L.6
Cravatt, B.F.7
-
9
-
-
79954625240
-
-
Pfizer accessdate2/13/11
-
Pfizer. A Phase 2a randomized, double-blinded, double dummy, placebo and active controlled, two-way cross-over, flare-enriched multi-centre clinical trial to examine the pain relief produced by 2 weeks of daily oral administration of a fatty acid amide hydrolase (FAAH) inhibitor PF-04457845 in patients with osteoarthritis of the knee, 2010. Available at: http://clinicaltrials.gov/ct2/results?term=NCT00981357 ; access date 2/13/11.
-
(2010)
A Phase 2a Randomized, Double-blinded, Double Dummy, Placebo and Active Controlled, Two-way Cross-over, Flare-enriched Multi-centre Clinical Trial to Examine the Pain Relief Produced by 2 Weeks of Daily Oral Administration of A Fatty Acid Amide Hydrolase (FAAH) Inhibitor PF-04457845 in Patients with Osteoarthritis of the Knee
-
-
-
10
-
-
77956903436
-
Recommendations for the use of preclinical models in the study and treatment of osteoarthritis
-
R. Poole, S. Blake, M. Buschmann, S. Goldring, S. Laverty, S. Lockwood, J. Matyas, J. McDougall, K. Pritzker, K. Rudolphi, W. van den Berg, and T. Yaksh Recommendations for the use of preclinical models in the study and treatment of osteoarthritis Osteoarthritis Cartilage 18 2010 S10 S16
-
(2010)
Osteoarthritis Cartilage
, vol.18
-
-
Poole, R.1
Blake, S.2
Buschmann, M.3
Goldring, S.4
Laverty, S.5
Lockwood, S.6
Matyas, J.7
McDougall, J.8
Pritzker, K.9
Rudolphi, K.10
Van Den Berg, W.11
Yaksh, T.12
-
11
-
-
0017349888
-
Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response
-
D. Raft, J. Gregg, J. Ghia, and L. Harris Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response Clin Pharmacol Ther 21 1977 26 33 (Pubitemid 8024156)
-
(1977)
Clinical Pharmacology and Therapeutics
, vol.21
, Issue.1
, pp. 26-33
-
-
Raft, D.1
Gregg, J.2
Ghia, J.3
Harris, L.4
-
12
-
-
43249115359
-
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
-
D. Richardson, R.G. Pearson, N. Kurian, M.L. Latif, M.J. Garle, D.A. Barrett, D.A. Kendall, B.E. Scammell, A.J. Reeve, and V. Chapman Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis Arthritis Res Ther 10 2008 R43
-
(2008)
Arthritis Res Ther
, vol.10
, pp. 43
-
-
Richardson, D.1
Pearson, R.G.2
Kurian, N.3
Latif, M.L.4
Garle, M.J.5
Barrett, D.A.6
Kendall, D.A.7
Scammell, B.E.8
Reeve, A.J.9
Chapman, V.10
-
13
-
-
78649878693
-
Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain
-
D.R. Sagar, L.E. Staniaszek, B.N. Okine, S. Woodhams, L.M. Norris, R.G. Pearson, M.J. Garle, S.P. Alexander, A.J. Bennett, D.A. Barrett, D.A. Kendall, B.E. Scammell, and V. Chapman Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain Arthritis Rheum 62 2010 3666 3676
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3666-3676
-
-
Sagar, D.R.1
Staniaszek, L.E.2
Okine, B.N.3
Woodhams, S.4
Norris, L.M.5
Pearson, R.G.6
Garle, M.J.7
Alexander, S.P.8
Bennett, A.J.9
Barrett, D.A.10
Kendall, D.A.11
Scammell, B.E.12
Chapman, V.13
-
14
-
-
65549121665
-
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation
-
J.E. Schlosburg, S.G. Kinsey, and A.H. Lichtman Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation AAPS J 11 2009 39 44
-
(2009)
AAPS J
, vol.11
, pp. 39-44
-
-
Schlosburg, J.E.1
Kinsey, S.G.2
Lichtman, A.H.3
-
15
-
-
79954616674
-
Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis
-
N. Schuelert, M.P. Johnson, J.L. Oskins, K. Jassal, M.G. Chambers, and J.J. McDougall Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis Pain 152 2011 975 981
-
(2011)
Pain
, vol.152
, pp. 975-981
-
-
Schuelert, N.1
Johnson, M.P.2
Oskins, J.L.3
Jassal, K.4
Chambers, M.G.5
McDougall, J.J.6
-
16
-
-
0037334206
-
Cannabis use for chronic non-cancer pain: Results of a prospective survey
-
DOI 10.1016/s0304-3959(02)00400-1
-
M.A. Ware, C.R. Doyle, R. Woods, M.E. Lynch, and A.J. Clark Cannabis use for chronic non-cancer pain: results of a prospective survey Pain 102 2003 211 216 (Pubitemid 36298878)
-
(2003)
Pain
, vol.102
, Issue.1-2
, pp. 211-216
-
-
Ware, M.A.1
Doyle, C.R.2
Woods, R.3
Lynch, M.E.4
Clark, A.J.5
-
17
-
-
33751425461
-
Evaluation of herbal cannabis characteristics by medical users: A randomized trial
-
M.A. Ware, T. Ducruet, and A.R. Robinson Evaluation of herbal cannabis characteristics by medical users: a randomized trial Harm Reduct J 3 2006 32
-
(2006)
Harm Reduct J
, vol.3
, pp. 32
-
-
Ware, M.A.1
Ducruet, T.2
Robinson, A.R.3
-
18
-
-
76249123626
-
The effects of nabilone on sleep in fibromyalgia: Results of a randomized controlled trial
-
M.A. Ware, M.A. Fitzcharles, L. Joseph, and Y. Shir The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial Anesth Analg 110 2010 604 610
-
(2010)
Anesth Analg
, vol.110
, pp. 604-610
-
-
Ware, M.A.1
Fitzcharles, M.A.2
Joseph, L.3
Shir, Y.4
-
19
-
-
77958035149
-
Smoked cannabis for chronic neuropathic pain: A randomized controlled trial
-
M.A. Ware, T. Wang, S. Shapiro, A. Robinson, T. Ducruet, T. Huynh, A. Gamsa, G.J. Bennett, and J.P. Collet Smoked cannabis for chronic neuropathic pain: a randomized controlled trial Can Med Assoc J 182 2010 E694 E701
-
(2010)
Can Med Assoc J
, vol.182
-
-
Ware, M.A.1
Wang, T.2
Shapiro, S.3
Robinson, A.4
Ducruet, T.5
Huynh, T.6
Gamsa, A.7
Bennett, G.J.8
Collet, J.P.9
-
20
-
-
33745616113
-
The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis [5]
-
DOI 10.1093/rheumatology/kel114
-
S. Wright, M. Ware, and G. Guy The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis Rheumatology (Oxford) 45 2006 781 (author reply 781-2) (Pubitemid 43985356)
-
(2006)
Rheumatology
, vol.45
, Issue.6
, pp. 781
-
-
Wright, S.1
Ware, M.2
Guy, G.3
|