8p11 myeloproliferative syndrome with BCR-FGFR1 rearrangement presenting with T-lymphoblastic lymphoma and bone marrow stromal cell proliferation: A case report and review of the literature

Leukemia Research

Volumn 35, Issue 5, 2011, Pages

  Kim, Seon Young ^a   Oh, Bora ^a   She, Cha Ja ^a   Kim, Hyun Kyung ^a   Jeon, Yoon Kyung ^a   Shin, Myung Geun ^b   Yoon, Sung Soo ^a   Lee, Dong Soon ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Chonnam National University Research Institute of Medical Sciences   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; DAUNORUBICIN; PREDNISONE; VINCRISTINE;

ABDOMINAL DISEASE; ABDOMINAL ENLARGEMENT; ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; BCR FGRR1 GENE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CELL PROLIFERATION; CERVICAL LYMPHADENOPATHY; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; GENE; GENE REARRANGEMENT; HEMATOPOIETIC STEM CELL; HEPATOSPLENOMEGALY; HUMAN; HUMAN CELL; LETTER; LYMPHADENOPATHY; LYMPHATIC LEUKEMIA; MALE; MYELOPROLIFERATIVE DISORDER; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SPLENOMEGALY; TONSIL DISEASE; TONSIL ENLARGEMENT; TREATMENT DURATION;

BONE MARROW CELLS; CELL PROLIFERATION; CHROMOSOMES, HUMAN, PAIR 22; CHROMOSOMES, HUMAN, PAIR 8; HUMANS; LYMPHOMA, T-CELL; MALE; MIDDLE AGED; MYELOPROLIFERATIVE DISORDERS; PROTO-ONCOGENE PROTEINS C-BCR; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECOMBINANT FUSION PROTEINS; STROMAL CELLS; SYNDROME; TRANSLOCATION, GENETIC;

EID: 79954575639     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.12.014     Document Type: Letter

References (15)

1. WHO classification of tumours of haematopoietic and lymphoid tissues 2008, 68-73. IARC, Lyon, France. S.H. Swerdlow, E. Champo, N.L. Harris (Eds.).
2. Shin M.G., Choi H.W., Kim H.R., Kim M.J., Baek H.J., Han D.K., et al. Tetrasomy 21 as a sole acquired abnormality without GATA1 gene mutation in pediatric acute megakaryoblastic leukemia: a case report and review of the literature. Leuk Res 2008, 32:1615-1619.
3. Demiroglu A., Steer E.J., Heath C., Taylor K., Bentley M., Allen S.L., et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood 2001, 98:3778-3783.
4. Soler G., Nusbaum S., Varet B., Macintyre E.A., Vekemans M., Romana S.P., et al. LRRFIP1, a new FGFR1 partner gene associated with 8p11 myeloproliferative syndrome. Leukemia 2009, 23:1359-1361.
5. Fioretos T., Panagopoulos I., Lassen C., Swedin A., Billstrom R., Isaksson M., et al. Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL. Genes Chromosomes Cancer 2001, 32:302-310.
6. Pini M., Gottardi E., Scaravaglio P., Giugliano E., Libener R., Baraldi A., et al. A fourth case of BCR-FGFR1 positive CML-like disease with t(8;22) translocation showing an extensive deletion on the derivative chromosome 8p. Hematol J 2002, 3:315-316.
7. Murati A., Arnoulet C., Lafage-Pochitaloff M., Adelaide J., Derre M., Slama B., et al. Dual lympho-myeloproliferative disorder in a patient with t(8;22) with BCR-FGFR1 gene fusion. Int J Oncol 2005, 26:1485-1492.
8. Agerstam H., Lilljebjorn H., Lassen C., Swedin A., Richter J., Vandenberghe P., et al. Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome. Genes Chromosomes Cancer 2007, 46:635-643.
9. Lee S.G., Park T.S., Lee S.T., Lee K.A., Song J., Kim J., et al. Rare translocations involving chromosome band 8p11 in myeloid neoplasms. Cancer Genet Cytogenet 2008, 186:127-129.
10. Richebourg S., Theisen O., Plantier I., Parry A., Soenen-Cornu V., Lepelley P., et al. Chronic myeloproliferative disorder with t(8;22)(p11;q11) can mime clonal cytogenetic evolution of authentic chronic myelogeneous leukemia. Genes Chromosomes Cancer 2008, 47:915-918.
11. Macdonald D., Reiter A., Cross N.C. The 8p11 myeloproliferative syndrome a distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematol 2002, 107:101-107.
12. Rao P.H., Cesarman G., Coleman M., Acaron S., Verma R.S. Cytogenetic evidence for extramedullary blast crisis with t(8;13)(q11;p11) in chronic myelomonocytic leukemia. Acta Haematol 1992, 88:201-203.
13. Inhorn R.C., Aster J.C., Roach S.A., Slapak C.A., Soiffer R., Tantravahi R., et al. A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity. Blood 1995, 85:1881-1887.
14. Keane C., Henden A., Mills T., Wood P. Myeloid and lymphoid neoplasm with FGFR1 abnormality. Br J Haematol 2009, 145:440.
15. Roumiantsev S., Krause D.S., Neumann C.A., Dimitri C.A., Asiedu F., Cross N.C., et al. Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations. Cancer Cell 2004, 5:287-298.