Chronic myeloproliferative disorder with t(8;22)(p11;q11) can mime clonal cytogenetic evolution of authentic chronic myelogeneous leukemia

Genes Chromosomes and Cancer

Volumn 47, Issue 10, 2008, Pages 915-918

  Richebourg, Steven ^a   Theisen, Olivier ^a   Plantier, Isabelle ^b   Parry, Anne ^b   Soenen Cornu, Valérie ^a,c   Lepelley, Pascale ^a,c   Preudhomme, Claude ^a,c   Renneville, Aline ^a   Laï, Jean Luc ^a   Roche Lestienne, Catherine ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b Service d'Hematologie Clinique   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ARSENIC TRIOXIDE; CYTARABINE; HYDROXYUREA;

ADULT; BCR GENE; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CANCER GROWTH; CASE REPORT; CHROMOSOME ABERRATION; CHRONIC MYELOID LEUKEMIA; CYTOGENETICS; FEMALE; FGFR1 GENE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE; HUMAN; HUMAN TISSUE; LETTER; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 50249168234     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20588     Document Type: Letter

References (19)

1. Agerstam H, Lilljebjörn H, Lassen C, Swedin A, Richter J, Vandenberghe P, Johansson B, Fioretos T. 2007. Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome. Genes Chromosomes Cancer 46:635-643.
2. Cross NC, Reiter A. 2002. Tyrosine kinase fusion genes in chronic myeloproliferative diseases. Leukemia 16:1207-1212.
3. Cuenco GM, Ren R. 2001. Cooperation of BCR-ABL and AML1/MDS1/EVI1 in blocking myeloid differentiation and rapid induction of an acute myelogenous leukaemia. Oncogene 20:8236-8248.
4. Cuenco GM, Ren R. 2004. Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice. Oncogene 23:569-579.
5. De Braekeleer E, Douet-Guilbert N, Le Bris MJ, Morel F, De Braekeleer M. 2007. Translocation 3;21, trisomy 8, and duplication of the Philadelphia chromosome: A rare but recurrent cytogenetic pathway in the blastic phase of chronic myeloid leukemia. Cancer Genet Cytogenet 179:159-161.
6. Demiroglu A, Steer EJ, Heath C, Taylor K, Bentley M, Allen SL, Koduru P, Brody JP, Hawson G, Rodwell R, Doody ML, Carnicero F, Reiter A, Goldman JM, Melo JV, Cross NC. 2001. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: Transforming activity and specific inhibition of FGFR1 fusion proteins. Blood 98:3778-3783.
7. Fioretos T, Panagopoulos I, Lassen C, Swedin A, Billström R, Isaksson M, Strömbeck B, Olofsson T, Mitelman F, Johansson B. 2001. Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: The first fusion gene involving BCR but not ABL. Genes Chromosomes Cancer 32:302-310.
8. Johansson B, Fioretos T, Mitelman F. 2002. Cytogenetic and molecular genetic evolution of chronic myeloid leukemia. Acta Haematol 107:76-94.
9. Macdonald D, Cross NC. 2007. Chronic myeloproliferative disorders: The role of tyrosine kinases in pathogenesis, diagnosis and therapy. Pathobiology 74:81-88.
10. Macdonald D, Reiter A, Cross NC. 2002. The 8p11 myeloproliferative syndrome: A distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematol 107:101-107.
11. Mitani K, Ogawa S, Tanaka T, Miyoshi H, Kurokawa M, Mano H, Yazaki Y, Ohki M, Hirai H. 1994. Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia. EMBO J 13:504-510.
12. Murati A, Arnoulet C, Lafage-Pochitaloff M, Adélaide J, Derré M, Slama B, Delaval B, Popovici C, Vey N, Xerri L, Mozziconacci MJ, Boulat O, Sainty D, Birnbaum D, Chaffanet M. 2005. Dual lympho- myeloproliferative disorder in a patient with t(8;22) with BCR-FGFR1 gene fusion. Int J Oncol 26:1485-1492.
13. Phan CL, Megat Baharuddin PJ, Chin LP, Zakaria Z, Yegappan S, Sathar J, Tan SM, Purushothaman V, Chang KM. 2008. Amplification of BCR-ABL and t(3;21) in a patient with blast crisis of chronic myelogenous leukemia. Cancer Genet Cytogenet 180:60-64.
14. Pini M, Gottardi E, Scaravaglio P, Giugliano E, Libener R, Baraldi A, Muzio A, Cornaglia E, Saglio G, Levis A. 2002. A fourth case of BCR-FGFR1 positive CML-like disease with t(8;22) translocation showing an extensive deletion on the derivative chromosome 8p. Hematol J 3:315-316.
15. Radich JP. The biology of CML blast crisis. 2007. Hematol Am Soc Hematol Edu Program 2007:384-391.
16. Roche-Lestienne C, Deluche L, Corm S, Tigaud I, Joha S, Philippe N, Geffroy S, Laï JL, Nicolini FE, Preudhomme C;on behalf of the Fi-LMC group. 2008. RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance. Blood 111:3735-3741.
17. Roumiantsev S, Krause DS, Neumann CA, Dimitri CA, Asiedu F, Cross NC, Van Etten RA. 2004. Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations. Cancer Cell 5:287-298.
18. Schoch C, Haferlach T, Kern W, Schnittger S, Berger U, Hehlmann R, Hiddemann W, Hochhaus A. 2003. Occurrence of additional chromosome aberrations in chronic myeloid leukemia patients treated with imatinib mesylate. Leukemia 17:461-463.
19. Wong WS, Cheng KC, Lau KM, Chan NP, Shing MM, Cheng SH, Chik KW, Li CK, Ng MH. 2007. Clonal evolution of 8p11 stem cell syndrome in a 14-year-old Chinese bov: A review of literature of t(8;13) associated myeloproliferative diseases. Leuk Res 31:235-238.