Recombinant adeno-associated virus-mediated in Utero gene transfer gives therapeutic transgene expression in the sheep

Human Gene Therapy

Volumn 22, Issue 4, 2011, Pages 419-426

  David, Anna L ^a   McIntosh, Jenny ^b   Peebles, Donald M ^a   Cook, Terry ^c   Waddington, Simon ^b   Weisz, Boaz ^a   Wigley, Victoria ^a   Abi Nader, Khalil ^a   Boyd, Michael ^d   Davidoff, Andrew M ^e   Nathwani, Amit C ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d ROYAL VETERINARY COLLEGE   (United Kingdom)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BILE ACID; BLOOD CLOTTING FACTOR 9; FREUND ADJUVANT; MESSENGER RNA; SELF COMPLEMENTARY ADENO ASSOCIATED VIRUS VECTOR; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE ACID BLOOD LEVEL; CONTROLLED STUDY; FEMALE; FETUS LIVER; FETUS WEIGHT; GENE EXPRESSION; LAMB; LIVER; LIVER FUNCTION; LIVER WEIGHT; MALE; NONHUMAN; PREGNANCY; PROTEIN EXPRESSION; RETROPERITONEUM; SEROTYPE; TRANSGENE; ULTRASOUND; VIRAL GENE DELIVERY SYSTEM; VIRUS GENOME; VIRUS RECOMBINANT;

ANIMALS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FACTOR IX; FEMALE; FETUS; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMOPHILIA B; HUMANS; MALE; SHEEP, DOMESTIC; TRANSGENES; TREATMENT OUTCOME;

ADENO-ASSOCIATED VIRUS; ANIMALIA; OVIS ARIES;

EID: 79954543052     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2010.007     Document Type: Article

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