Gas chromatography/combustion/isotope ratio mass spectrometric comparison of N-acetyl- and N-pivaloyl amino acid esters to measure 15N isotopic abundances in physiological samples: A pilot study on amino acid synthesis in the upper gastro-intestinal tract of minipigs

Journal of Mass Spectrometry

Volumn 31, Issue 4, 1996, Pages 367-376

  Metges, Cornelia C ^a,c   Petzke, Klaus Jürgen ^a   Hennig, Ulf ^b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Amino acids; Gas chromatography combustion isotope ratio mass spectrometry; Gut microflora; Lysine; Stable isotopes

Indexed keywords

ANIMALIA;

LYSINE;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GAS CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; MICROFLORA; NONHUMAN; PRIORITY JOURNAL; SWINE; UPPER GASTROINTESTINAL TRACT;

ACETYLATION; AMINO ACIDS; ANIMALS; DIGESTIVE SYSTEM; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROLYSIS; ILEUM; MALE; NITROGEN ISOTOPES; PENTANOIC ACIDS; PILOT PROJECTS; RECTUM; SWINE; SWINE, MINIATURE;

EID: 0029879632     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199604)31:4<367::AID-JMS310>3.0.CO;2-V     Document Type: Review

References (30)

1. R. Schoenheimer, S. Ratner and D. Rittenberg, J. Biol. Chem. 130, 703 (1939).
2. R. Schoenheimer, S. Ratner and D. Rittenberg, J. Biol. Chem. 127, 333 (1939).
3. J. T. Brenna, Acc. Chem Res. 27, 340 (1994).
4. T. Preston and C. Slater, Proc. Nutr. Soc. 53, 363 (1994).
5. D. E. Matthews and J. M. Hayes, Anal. Chem. 50, 1465 (1978).
6. C. C. Metges, K. Kempe and G. Wolfram. Biol. Mass Spectrom. 23, 295 (1994).
7. S. Tissot, S. Normand, R. Guilly, C. Pachiaudi, M. Beylot. M. Laville, R. Chen, R. Mornex and J. P. Riou, Diabetiologica 33, 449 (1990).
8. H. Demmelmair and H.-L. Schmidt, Isotopenpraxis Environ. Health Stud. 23, 237 (1993)
9. D. A. Merrit and J. M. Hayes, J. Am. Soc. Mass Spectrom. 5, 387 (1994).
10. W. A. Brand, A. R. Tegtmeyer and A. Hilkert, Org. Geochem. 21, 585 (1994).
11. E. Deguchi and S. Namioka, Bifidobact. Microflora 8, 1 (1988)
12. D. Torrallardona, C. I. Harris, E. Milne and M. F. Fuller, EAAP Publication, No. 55, p. 245, VIth Int. Congr. Digest. Physiol. in Pigs, Bad Doberan, Series of the Forschungsinstitut für die Biologie laudwirtschaftlicher Nutztiere, edited by P. Kauffold, Germany (1994).
13. C. Giordano, C. De Pascale, C. Balestrieri, D. Cittadini and A. Crescenzi, Am. J. Clin. Nutr. 21, 394 (1968).
14. N. Tanaka, K. Katsuharu, K. Shiraki, H. Koishi and H. Yoshimura, J. Nutr. Sci. Vitaminol. 26, 247 (1980).
15. A. A. Jackson, Lancet i, 1034 (1983).
16. B. W. Patterson, F. Carraro, S. Klein and R. R. Wolfe, Am. J. Physiol. 269, E508 (1995).
17. B. W. Patterson, F. Carraro and R. R. Wolfe, Biol. Mass Spectrom. 22, 518 (1993).
18. D. E. Matthews, J. M. Conway, V. R. Young and D. M. Bier, Metabolism 30, 886 (1981).
19. U. Hennig, R. Noel, U. Herrmann, J. Wuensche and E. Mehnert, Arch. Tierernaehr. 36, 585 (1986).
20. U. Hennig, J. Wünsche, W. B. Souffrant and U. Herrmann, Arch. Exp. Vet.-Med. 44, 35 (1990).
21. H. F. Boeden, K. Pommering, M. Becker, C. Rupprich, M. Holtzhauer, F. Loth, R. Müller and D. Bertram, J. Chromatogr. 552, 389 (1991).
22. J. A. Silfer, M. H. Engel, S. A. Macko and E. J. Jumeau, Anal. Chem. 63, 370 (1991).
23. R. Aichholz and P, Fischer, J. High Resolut. Chromatogr. 12, 213 (1989).
24. K. J. Goodman and J. T. Brenna. Anal. Chem. 66, 1294 (1994).
25. A. L. Lehninger, D. L. Nelson and M. M. Cox, Principles of Biochemistry, 2nd edn. Worth, New York (1993).
26. Y.-B. Sheng, T. M. Badger, J. M. Asplund and R. L. Wixom, J. Nutr. 107, 621 (1977).
27. R. P. Cox and J. Dancis, in The Metabolic and Molecular Bases of Inherited Disease, edited by C. R. Shriver, A. L. Beaudet, W. S. Sly and D. Valle. Vol. 1, 7th edn, p. 33. McGraw-Hill, New York (1995).
28. S. M. Finegold, V. L. Sutter and G. E. Mathisen, in Human Intestinal Microflora in Health and Disease, edited by D. J. Hentges, p. 3. Academic Press, New York (1983).
29. D. Matteuzi, F. Grociani and O. Emaldi, Ann. Microbiol. (Inst. Pasteur) 129B, 175 (1978).
30. J. Wünsche, T. Voelker, E. Borgmann and W. B. Souffrant, EAAP Publication, No. 54, p. 310. Vth Int. Congr. Digest. Physiol. in Pigs, Wageningen, The Netherlands (1991).