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Volumn 9, Issue 4, 2011, Pages 430-439

Apoptosis is the essential target of selective pressure against p53, whereas loss of additional p53 functions facilitates carcinoma progression

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BAX; PROTEIN P53;

EID: 79954513124     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-10-0277     Document Type: Article
Times cited : (4)

References (30)
  • 2
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • DOI 10.1002/humu.20495
    • Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007;28:622-9. (Pubitemid 46744292)
    • (2007) Human Mutation , vol.28 , Issue.6 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6    Olivier, M.7
  • 3
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994;265:1582-4. (Pubitemid 24308973)
    • (1994) Science , vol.265 , Issue.5178 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 4
    • 0029972806 scopus 로고    scopus 로고
    • P53:Puzzle and paradigm
    • Ko LJ, Prives C. P53: puzzle and paradigm. Genes Dev 1996;10:1054-72.
    • (1996) Genes Dev , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 5
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • DOI 10.1016/S0092-8674(00)81871-1
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31. (Pubitemid 27131374)
    • (1997) Cell , vol.88 , Issue.3 , pp. 323-331
    • Levine, A.J.1
  • 7
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • DOI 10.1038/nrc864
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002;2:594-604. (Pubitemid 37328926)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.8 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 8
    • 0029134878 scopus 로고
    • Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis
    • Hsu B, Marin MC, el-Naggar AK, Stephens LC, Brisbay S, McDonnell TJ. Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis. Oncogene 1995;11:175-9.
    • (1995) Oncogene , vol.11 , pp. 175-179
    • Hsu, B.1    Marin, M.C.2    El-Naggar, A.K.3    Stephens, L.C.4    Brisbay, S.5    McDonnell, T.J.6
  • 9
    • 0034775395 scopus 로고    scopus 로고
    • Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis
    • DOI 10.1128/MCB.21.22.7653-7662.2001
    • Eischen CM, Roussel MF, Korsmeyer SJ, Cleveland JL. Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. Mol Cell Biol 2001;21:7653-62. (Pubitemid 32988776)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.22 , pp. 7653-7662
    • Eischen, C.M.1    Roussel, M.F.2    Korsmeyer, S.J.3    Cleveland, J.L.4
  • 13
    • 0026039802 scopus 로고
    • Uniform Cell-Autonomous Tumorigenesis of the Choroid Plexus by Papovavirus Large T Antigens
    • Chen JD, Van Dyke T. Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens. Mol Cell Biol 1991;11:5968-76. (Pubitemid 21895366)
    • (1991) Molecular and Cellular Biology , vol.11 , Issue.12 , pp. 5968-5976
    • Chen, J.1    Van Dyke, T.2
  • 14
    • 0028169994 scopus 로고
    • P53-dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T, et al. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994;78:703-11.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Remington, L.3    Saenz-Robles, M.4    Lowe, S.5    Jacks, T.6
  • 15
    • 0031038137 scopus 로고    scopus 로고
    • Bax suppresses tumorigenesis and stimulates apoptosis in vivo
    • DOI 10.1038/385637a0
    • Yin C, Knudson CM, Korsmeyer SJ, Van Dyke T. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 1997;385: 637-40. (Pubitemid 27087577)
    • (1997) Nature , vol.385 , Issue.6617 , pp. 637-640
    • Yin, C.1    Knudson, C.M.2    Korsmeyer, S.J.3    Van Dyke, T.4
  • 16
    • 0034909856 scopus 로고    scopus 로고
    • Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability
    • DOI 10.1128/MCB.21.17.6017-6030.2001
    • Lu X, Magrane G, Yin C, Louis DN, Gray J, Van Dyke T. Selective inactivation of p53 facilitates mouse epithelial tumor progression without chromosomal instability. Mol Cell Biol 2001;21:6017-30. (Pubitemid 32737816)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.17 , pp. 6017-6030
    • Lu, X.1    Magrane, G.2    Yin, C.3    Louis, D.N.4    Gray, J.5    Van Dyke, T.6
  • 17
    • 0028226679 scopus 로고
    • Induction versus progression of brain tumor development: Differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen
    • Saenz Robles MT, Symonds H, Chen J, Van Dyke T. Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen. Mol Cell Biol 1994;14:2686-98. (Pubitemid 24108250)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.4 , pp. 2686-2698
    • Saenz Robles, M.T.1    Symonds, H.2    Chen, J.3    Van Dyke, T.4
  • 22
    • 45549097099 scopus 로고    scopus 로고
    • Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival
    • Lu X, Yang C, Hill R, Yin C, Hollander MC, Fornace AJ Jr, Van Dyke T. Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival. Cancer Research 2008;68:3579-83.
    • (2008) Cancer Research , vol.68 , pp. 3579-3583
    • Lu, X.1    Yang, C.2    Hill, R.3    Yin, C.4    Hollander, M.C.5    Fornace Jr., A.J.6    Van Dyke, T.7
  • 23
    • 0032160407 scopus 로고    scopus 로고
    • Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors
    • Pan H, Yin C, Dyson NJ, Harlow E, Yamasaki L, Van Dyke T. Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Mol Cell 1998;2:283-92. (Pubitemid 128379269)
    • (1998) Molecular Cell , vol.2 , Issue.3 , pp. 283-292
    • Pan, H.1    Yin, C.2    Dyson, N.J.3    Harlow, E.4    Yamasaki, L.5    Van Dyke, T.6
  • 26
    • 0029045784 scopus 로고
    • Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
    • Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, et al. Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res 1995;55:4471-8.
    • (1995) Cancer Res , vol.55 , pp. 4471-448
    • Krajewski, S.1    Blomqvist, C.2    Franssila, K.3    Krajewska, M.4    Wasenius, V.M.5    Niskanen, E.6
  • 27
    • 0032768021 scopus 로고    scopus 로고
    • Prognostic significance of proliferative and apoptotic markers in oral tongue squamous cell carcinomas
    • DOI 10.1016/S1368-8375(99)00024-X, PII S136883759900024X
    • Xie X, De Angelis P, Clausen OP, Boysen M. Prognostic significance of proliferative and apoptotic markers in oral tongue squamous cell carcinomas. Oral Oncol 1999;35:502-9. (Pubitemid 29386787)
    • (1999) Oral Oncology , vol.35 , Issue.5 , pp. 502-509
    • Xie, X.1    De Angelis, P.2    Clausen, O.P.F.3    Boysen, M.4
  • 28
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • DOI 10.1126/science.275.5302.967
    • Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997;275: 967-9. (Pubitemid 27087710)
    • (1997) Science , vol.275 , Issue.5302 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3    Li, Y.4    Sawai, H.5    Reed, J.C.6    Perucho, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.