메뉴 건너뛰기




Volumn 4, Issue 2, 2011, Pages 150-157

Effects of a long-term treatment with an antioxidant pyridoindole on vascular responsiveness in diabetes-induced aging rats

Author keywords

Aged rat; Antioxidants; Calcium; Diabetes; Pyridoindole; Vascular

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ACETYLCHOLINE; CALCIUM ION; CYCLOPIAZONIC ACID; PHENYLEPHRINE; STOBADINE; THAPSIGARGIN;

EID: 79954486205     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609811104020150     Document Type: Article
Times cited : (6)

References (42)
  • 1
    • 21244491603 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Do women differ from men?
    • Ren J, Ceylan-Isik AF. Diabetic cardiomyopathy: do women differ from men? Endocrine 2004; 25: 73-83.
    • (2004) Endocrine , vol.25 , pp. 73-83
    • Ren, J.1    Ceylan-Isik, A.F.2
  • 2
    • 65849407900 scopus 로고    scopus 로고
    • Hypertension and diabetes: A toxic combination
    • Bell DS. Hypertension and diabetes: a toxic combination. Endocr Pract 2008; 14: 1031-9.
    • (2008) Endocr Pract , vol.14 , pp. 1031-1039
    • Bell, D.S.1
  • 3
    • 0344848578 scopus 로고    scopus 로고
    • Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution
    • Fleischhacker E, Esenabhalu VE, Spitaler M, Holzmann S, Skrabal F, Koidl B, et al. Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution. Diabetes 1999; 48: 1323-30.
    • (1999) Diabetes , vol.48 , pp. 1323-1330
    • Fleischhacker, E.1    Esenabhalu, V.E.2    Spitaler, M.3    Holzmann, S.4    Skrabal, F.5    Koidl, B.6
  • 4
    • 0034536369 scopus 로고    scopus 로고
    • Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reactivity and morphology of vessels already damaged by streptozotocin-diabetes
    • Koçak G, Aktan F, Canbolat O, Ozoǧul C, Elbeg S, Yildizoglu-Ari N, et al. Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reactivity and morphology of vessels already damaged by streptozotocin-diabetes. Diabetes Nutr Metab 2000; 13: 308-18.
    • (2000) Diabetes Nutr Metab , vol.13 , pp. 308-318
    • Koçak, G.1    Aktan, F.2    Canbolat, O.3    Ozoǧul, C.4    Elbeg, S.5    Yildizoglu-Ari, N.6
  • 5
    • 0036211948 scopus 로고    scopus 로고
    • Elimination of *O(2)(-)/H(2)O(2) by alphalipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta
    • Koçak G, Karasu C. Elimination of *O(2)(-)/H(2)O(2) by alphalipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta. Diabetes Obes Metab 2002; 4: 69-74.
    • (2002) Diabetes Obes Metab , vol.4 , pp. 69-74
    • Koçak, G.1    Karasu, C.2
  • 6
    • 58549094758 scopus 로고    scopus 로고
    • The pathologic continuum of diabetic vascular disease
    • Orasanu G, Plutzky J. The pathologic continuum of diabetic vascular disease. J Am Coll Cardiol 2009; 53: S35-42.
    • (2009) J Am Coll Cardiol , vol.53
    • Orasanu, G.1    Plutzky, J.2
  • 9
    • 0345676510 scopus 로고    scopus 로고
    • Antioxidant and pharmacodynamic effects of pyridoindole stobadine
    • Horakova L, Stolc S. Antioxidant and pharmacodynamic effects of pyridoindole stobadine. Gen Pharmacol 1998; 30: 627-38.
    • (1998) Gen Pharmacol , vol.30 , pp. 627-638
    • Horakova, L.1    Stolc, S.2
  • 10
    • 0034489540 scopus 로고    scopus 로고
    • Effect of dietary supplementation with the pyridoindole antioxidant stobadine on antioxidant state and ultrastructure of diabetic rat myocardium
    • Stefek M, Sotnikova R, Okruhlicova L, Volkovova K, Kucharska J, Gajdosik A, et al. Effect of dietary supplementation with the pyridoindole antioxidant stobadine on antioxidant state and ultrastructure of diabetic rat myocardium. Acta Diabetol 2000; 37: 111-7.
    • (2000) Acta Diabetol , vol.37 , pp. 111-117
    • Stefek, M.1    Sotnikova, R.2    Okruhlicova, L.3    Volkovova, K.4    Kucharska, J.5    Gajdosik, A.6
  • 11
    • 0037048615 scopus 로고    scopus 로고
    • Antioxidants in Diabetes-Induced Complications Study Group. In vivo treatment with stobadine prevents lipid peroxidation, protein glycation and calcium overload but does not ameliorate Ca2+-ATPase activity in heart and liver of streptozotocindiabetic rats: Comparison with vitamin
    • Pekiner B, Ulusu NN, Das-Evcimen N, Sahilli M, Aktan F, Stefek M, et al. Antioxidants in Diabetes-Induced Complications Study Group. In vivo treatment with stobadine prevents lipid peroxidation, protein glycation and calcium overload but does not ameliorate Ca2+-ATPase activity in heart and liver of streptozotocindiabetic rats: comparison with vitamin E. Biochim Biophys Acta 2002; 1588: 71-8.
    • (2002) E. Biochim Biophys Acta , vol.1588 , pp. 71-78
    • Pekiner, B.1    Ulusu, N.N.2    Das-Evcimen, N.3    Sahilli, M.4    Aktan, F.5    Stefek, M.6
  • 12
    • 0036873473 scopus 로고    scopus 로고
    • The pyridoindole antioxidant stobadine attenuates albuminuria, enzymuria, kidney lipid peroxidation and matrix collagen cross-linking in streptozotocin-induced diabetic rats
    • Stefek M, Gajdosik A, Tribulova N, Navarova J, Volkovova K, Weismann P, et al. The pyridoindole antioxidant stobadine attenuates albuminuria, enzymuria, kidney lipid peroxidation and matrix collagen cross-linking in streptozotocin-induced diabetic rats. Methods Find Exp Clin Pharmacol 2002; 24: 565-71.
    • (2002) Methods Find Exp Clin Pharmacol , vol.24 , pp. 565-571
    • Stefek, M.1    Gajdosik, A.2    Tribulova, N.3    Navarova, J.4    Volkovova, K.5    Weismann, P.6
  • 13
    • 34249990014 scopus 로고    scopus 로고
    • Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: Involvement of oxidative stres
    • Yulek F, Or M, Ozoǧul C, Isik AC, Ari N, Stefek M, et al. Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stres. Arch Med Res 2007; 38: 503-11.
    • (2007) Arch Med Res , vol.38 , pp. 503-511
    • Yulek, F.1    Or, M.2    Ozoǧul, C.3    Isik, A.C.4    Ari, N.5    Stefek, M.6
  • 14
    • 47849124034 scopus 로고    scopus 로고
    • Effects of antioxidant stobadine on protein carbonylation, advanced oxidation protein products and reductive capacity of liver in streptozotocindiabetic rats: Role of oxidative/nitrosative stress
    • Cumaoglu A, Cevik C, Rackova L, Ari N, Karasu C. Effects of antioxidant stobadine on protein carbonylation, advanced oxidation protein products and reductive capacity of liver in streptozotocindiabetic rats: role of oxidative/nitrosative stress. Biofactors 2007; 30: 171-8.
    • (2007) Biofactors , vol.30 , pp. 171-178
    • Cumaoglu, A.1    Cevik, C.2    Rackova, L.3    Ari, N.4    Karasu, C.5
  • 15
    • 0034894589 scopus 로고    scopus 로고
    • Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocindiabetic rats
    • Sotnikova R, Stefek M, Okruhlicova L, Navarova J, Bauer V, Gajdosik A, et al. Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocindiabetic rats. Methods Find Exp Clin Pharmacol 2001; 23: 121-9.
    • (2001) Methods Find Exp Clin Pharmacol , vol.23 , pp. 121-129
    • Sotnikova, R.1    Stefek, M.2    Okruhlicova, L.3    Navarova, J.4    Bauer, V.5    Gajdosik, A.6
  • 16
    • 0034894589 scopus 로고    scopus 로고
    • Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocindiabetic rats
    • Sotnikova R, Stefek M, Okruhlicova L, Navarova J, Bauer V, Gajdosik A, et al. Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocindiabetic rats. Methods Find Exp Clin Pharmacol 2001; 23: 121-9.
    • (2001) Methods Find Exp Clin Pharmacol , vol.23 , pp. 121-129
    • Sotnikova, R.1    Stefek, M.2    Okruhlicova, L.3    Navarova, J.4    Bauer, V.5    Gajdosik, A.6
  • 17
    • 0037409980 scopus 로고    scopus 로고
    • Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: Effects of stobadine and vitamin
    • Ulusu NN, Sahilli M, Avci A, Canbolat O, Ozansoy G, Ari N, et al. Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E. Neurochem Res 2003; 28: 815-23.
    • (2003) E. Neurochem Res , vol.28 , pp. 815-823
    • Ulusu, N.N.1    Sahilli, M.2    Avci, A.3    Canbolat, O.4    Ozansoy, G.5    Ari, N.6
  • 18
    • 33845234511 scopus 로고    scopus 로고
    • Changes in the function and ultrastructure of vessels in the rat model of multiple low dose streptozotocin-induced diabetes
    • Sotnikova R, Skalska S, Okruhlicova L, Navarova J, Kyselova Z, Zurova J, et al. Changes in the function and ultrastructure of vessels in the rat model of multiple low dose streptozotocin-induced diabetes. Gen Physiol Biophys 2006; 25: 289-302.
    • (2006) Gen Physiol Biophys , vol.25 , pp. 289-302
    • Sotnikova, R.1    Skalska, S.2    Okruhlicova, L.3    Navarova, J.4    Kyselova, Z.5    Zurova, J.6
  • 19
    • 13444270631 scopus 로고    scopus 로고
    • The Antioxidants in Diabetes-induced Complications (ADIC) Study Group. Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: Effects of in vivo treatment with antioxidants
    • Gunes A, Ceylan A, Sarioglu Y, Stefek M, Bauer V, Karasu C. The Antioxidants in Diabetes-induced Complications (ADIC) Study Group. Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: effects of in vivo treatment with antioxidants. Fundam Clin Pharmacol 2006; 19: 73-9.
    • (2006) Fundam Clin Pharmacol , vol.19 , pp. 73-79
    • Gunes, A.1    Ceylan, A.2    Sarioglu, Y.3    Stefek, M.4    Bauer, V.5    Karasu, C.6
  • 22
    • 0015576365 scopus 로고
    • Validation in awake rats of a tail-cuff method for measuring systolic pressure
    • Bunag RD. Validation in awake rats of a tail-cuff method for measuring systolic pressure. J Appl Physiol 1973; 34: 279-82.
    • (1973) J Appl Physiol , vol.34 , pp. 279-282
    • Bunag, R.D.1
  • 23
    • 79954504622 scopus 로고    scopus 로고
    • Role of endothelium in thapsigargin-induced arterial responses in rat aorta
    • Huang Y, Yao X, Lau C, Chan FL, Chan NW, Cheng Y, et al. Role of endothelium in thapsigargin-induced arterial responses in rat aorta. Eur J Pharmacol 2000; 24: 1-9.
    • (2000) Eur J Pharmacol , vol.24 , pp. 1-9
    • Huang, Y.1    Yao, X.2    Lau, C.3    Chan, F.L.4    Chan, N.W.5    Cheng, Y.6
  • 24
    • 0029936820 scopus 로고    scopus 로고
    • Enhanced contractile responses of arteries from streptozotocin diabetic rats to sodium fluoride
    • Weber LP, Chow WL, Abebe W, MacLeod KM. Enhanced contractile responses of arteries from streptozotocin diabetic rats to sodium fluoride. Br J Pharmacol 1996; 118: 115-22.
    • (1996) Br J Pharmacol , vol.118 , pp. 115-122
    • Weber, L.P.1    Chow, W.L.2    Abebe, W.3    Macleod, K.M.4
  • 25
    • 62149136644 scopus 로고    scopus 로고
    • Anesthesia, calcium homeostasis and Alzheimer's disease
    • Wei H, Xie Z. Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res 2009; 6: 30-5.
    • (2009) Curr Alzheimer Res , vol.6 , pp. 30-35
    • Wei, H.1    Xie, Z.2
  • 26
    • 0035031176 scopus 로고    scopus 로고
    • Contractile responses of diabetic rat aorta to phenylephrine at different stages of diabetic duration
    • Zhu BH, Guan YY, Min J, He H. Contractile responses of diabetic rat aorta to phenylephrine at different stages of diabetic duration. Acta Pharmacol Sin 2001; 22: 445-9.
    • (2001) Acta Pharmacol Sin , vol.22 , pp. 445-449
    • Zhu, B.H.1    Guan, Y.Y.2    Min, J.3    He, H.4
  • 27
    • 0030611403 scopus 로고    scopus 로고
    • Augmented Ca2+ influx is involved in the mechanism of enhanced proliferation of cultured vascular smooth muscle cells from spontaneously diabetic Goto-Kakizaki rats
    • Yoo HJ, Kozaki K, Akishita M, Watanabe M, Eto M, Nagano K, et al. Augmented Ca2+ influx is involved in the mechanism of enhanced proliferation of cultured vascular smooth muscle cells from spontaneously diabetic Goto-Kakizaki rats. Atherosclerosis 1997; 131: 167-75.
    • (1997) Atherosclerosis , vol.131 , pp. 167-175
    • Yoo, H.J.1    Kozaki, K.2    Akishita, M.3    Watanabe, M.4    Eto, M.5    Nagano, K.6
  • 28
    • 41749089352 scopus 로고    scopus 로고
    • Abnormalities of sarcoplasmic reticulum Ca2+ mobilization in aortic smooth muscle cells from streptozotocin-induced diabetic rats
    • Ma L, Zhu B, Chen X, Liu J, Guan Y, Ren J. Abnormalities of sarcoplasmic reticulum Ca2+ mobilization in aortic smooth muscle cells from streptozotocin-induced diabetic rats. Clin Exp Pharmacol Physiol 2008; 35: 568-73.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 568-573
    • Ma, L.1    Zhu, B.2    Chen, X.3    Liu, J.4    Guan, Y.5    Ren, J.6
  • 29
    • 33748673785 scopus 로고    scopus 로고
    • Calcium homeostasis and diabetes mellitus
    • Yamaguchi T, Sugimoto T. Calcium homeostasis and diabetes mellitus. Clin Calcium 2006; 16: 1270-5.
    • (2006) Clin Calcium , vol.16 , pp. 1270-1275
    • Yamaguchi, T.1    Sugimoto, T.2
  • 30
    • 15044340889 scopus 로고    scopus 로고
    • Angiotensin II Ca2+ signaling in rat afferent arterioles: Stimulation of cyclic ADP ribose and IP3 pathways
    • Fellner SK, Arendshorst WJ. Angiotensin II Ca2+ signaling in rat afferent arterioles: Stimulation of cyclic ADP ribose and IP3 pathways. Am J Physiol Renal Physiol 2005; 288: F785-91.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Fellner, S.K.1    Arendshorst, W.J.2
  • 31
    • 32944482523 scopus 로고    scopus 로고
    • Evidence for capacitative and non-capacitative Ca2+ entry pathways coexist in A10 vascular smooth muscle cells
    • Zhou JG, Qiu QY, Zhang Z, Liu YJ, Guan YY. Evidence for capacitative and non-capacitative Ca2+ entry pathways coexist in A10 vascular smooth muscle cells. Life Sci 2006; 78: 1558-63.
    • (2006) Life Sci , vol.78 , pp. 1558-1563
    • Zhou, J.G.1    Qiu, Q.Y.2    Zhang, Z.3    Liu, Y.J.4    Guan, Y.Y.5
  • 32
    • 0141706414 scopus 로고    scopus 로고
    • Diabetesinduced activation of protein kinase C inhibits store-operated Ca2+ uptake in rat retinal microvascular smooth muscle
    • Curtis TM, Major EH, Trimble ER, Scholfield CN. Diabetesinduced activation of protein kinase C inhibits store-operated Ca2+ uptake in rat retinal microvascular smooth muscle. Diabetologia 2003; 46: 1252-9.
    • (2003) Diabetologia , vol.46 , pp. 1252-1259
    • Curtis, T.M.1    Major, E.H.2    Trimble, E.R.3    Scholfield, C.N.4
  • 33
    • 0028945690 scopus 로고
    • Control of pulmonary vascular smooth muscle tone by sarcoplasmic reticulum Ca2+ pump blockers: Thapsigargin and cyclopiazonic acid
    • Gonzalez De La Fuente P, Savineau JP, Marthan R. Control of pulmonary vascular smooth muscle tone by sarcoplasmic reticulum Ca2+ pump blockers: Thapsigargin and cyclopiazonic acid. Pflügers Arch 1995; 429: 617-24.
    • (1995) Pflügers Arch , vol.429 , pp. 617-624
    • de la Gonzalez Fuente, P.1    Savineau, J.P.2    Marthan, R.3
  • 34
    • 0030992378 scopus 로고    scopus 로고
    • The effects of cyclopiazonic acid on intracellular Ca2+ in aortic smooth muscle cells from DOCA-hypertensive rats
    • Tostes RC, Wilde DW, Bendhack LM, Webb RC. The effects of cyclopiazonic acid on intracellular Ca2+ in aortic smooth muscle cells from DOCA-hypertensive rats. Braz J Med Biol Res 1997; 30: 257-67.
    • (1997) Braz J Med Biol Res , vol.30 , pp. 257-267
    • Tostes, R.C.1    Wilde, D.W.2    Bendhack, L.M.3    Webb, R.C.4
  • 35
    • 0037628056 scopus 로고    scopus 로고
    • Free radicalinduced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum
    • Kaplan P, Babusikova E, Lehotsky J, Dobrota D. Free radicalinduced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum. Mol Cell Biochem 2003; 248: 41-7.
    • (2003) Mol Cell Biochem , vol.248 , pp. 41-47
    • Kaplan, P.1    Babusikova, E.2    Lehotsky, J.3    Dobrota, D.4
  • 36
    • 53649109982 scopus 로고    scopus 로고
    • Paracrine effects of endothelial cells in a diabetic mouse model: Capacitative calcium entry stimulated thromboxane release
    • Okon EB, Golbabaie A, Breemen C. Paracrine effects of endothelial cells in a diabetic mouse model: capacitative calcium entry stimulated thromboxane release. Horm Metab Res 2008; 40: 645-50.
    • (2008) Horm Metab Res , vol.40 , pp. 645-650
    • Okon, E.B.1    Golbabaie, A.2    Breemen, C.3
  • 37
    • 0024419087 scopus 로고
    • The effects of type-1 and type-2 diabetes on endothelium-dependent relaxation in rat aorta
    • Altan VM, Karasu C, Ozüari A. The effects of type-1 and type-2 diabetes on endothelium-dependent relaxation in rat aorta. Pharmacol Biochem Behav 1989; 33: 519-22.
    • (1989) Pharmacol Biochem Behav , vol.33 , pp. 519-522
    • Altan, V.M.1    Karasu, C.2    Ozüari, A.3
  • 38
    • 0027212817 scopus 로고
    • The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: Effects of insulin treatment
    • Karasu C, Altan VM. The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: effects of insulin treatment. Gen Pharmacol 1993; 24: 743-55.
    • (1993) Gen Pharmacol , vol.24 , pp. 743-755
    • Karasu, C.1    Altan, V.M.2
  • 39
    • 4544286550 scopus 로고    scopus 로고
    • The endothelium in health and disease: A discussion of the contribution of nonnitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes
    • Triggle CR, Ding H, Anderson TJ, Pannirselvam M. The endothelium in health and disease: a discussion of the contribution of nonnitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. Mol Cell Biochem 2004; 263: 21-7.
    • (2004) Mol Cell Biochem , vol.263 , pp. 21-27
    • Triggle, C.R.1    Ding, H.2    Anderson, T.J.3    Pannirselvam, M.4
  • 40
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S, Palmer RMJ, Higgs EAA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.A.3
  • 41
    • 0015502074 scopus 로고
    • A23187: A divalent cation ionophore
    • Reed PW, Lardy HA. A23187: a divalent cation ionophore. J Biol Chem 1972; 247: 6970-7.
    • (1972) J Biol Chem , vol.247 , pp. 6970-6977
    • Reed, P.W.1    Lardy, H.A.2
  • 42
    • 0030870142 scopus 로고    scopus 로고
    • Central role of intracellular calcium stores in acute flow- and agonist-evoked endothelial nitric oxide release
    • Hutcheson IR, Griffith TM. Central role of intracellular calcium stores in acute flow- and agonist-evoked endothelial nitric oxide release. Br J Pharmacol 1997; 122: 117-25.
    • (1997) Br J Pharmacol , vol.122 , pp. 117-125
    • Hutcheson, I.R.1    Griffith, T.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.