Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells

Journal of Oral Pathology and Medicine

Volumn 40, Issue 5, 2011, Pages 390-396

  Lee, Shiuan Shinn ^a   Tseng, Ling Hsien ^a   Li, Yi Ching ^a   Tsai, Chung Hung ^b   Chang, Yu Chao ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Areca quid; Arecoline; Heat shock protein 47; Oral squamous cell carcinoma; Regulatory mechanisms

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; ARECOLINE; BIOLOGICAL MARKER; GLUTATHIONE; HEAT SHOCK PROTEIN 47; HERBIMYCIN A; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE;

ARTICLE; CHROMOSOME 11Q; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE LOCATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUTH CARCINOMA; MOUTH MUCOSA; ORAL BIOPSY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; UPREGULATION; WESTERN BLOTTING;

ACETYLCYSTEINE; ARECA; ARECOLINE; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CHOLINERGIC AGONISTS; CYCLOOXYGENASE 2; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HSP47 HEAT-SHOCK PROTEINS; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM STAGING; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 79954474354     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2010.00998.x     Document Type: Article

References (41)

1. Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC. Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J Oral Pathol Med 1995; 24: 450-3.
2. Gupta PC, Warnakulasuriya S. Global epidemiology of areca nut usage. Addict Biol 2002; 7: 77-83.
3. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Betel-quid and areca-nut chewing and some areca-nut derived nitrosamines. IARC Monogr Eval Carcinog Risks Hum 2004; 85: 1-334.
4. Tsai CH, Hsieh YS, Yang SF, Chou MY, Chang YC. Matrix metalloproteinase 2 and 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations. Oral Surg Oral Med Oral Pathol 2003; 95: 710-6.
5. Lee SS, Yang SF, Ho YC, Tsai CH, Chang YC. The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas. Oral Oncol 2008; 44: 180-6.
6. Lee SS, Yang SF, Tsai CH, Chou MC, Chou MY, Chang YC. Upregulation of heme oxygenase-1 expression in areca-quid-chewing-associated oral squamous cell carcinoma. J Formos Med Assoc 2008; 107: 355-63.
7. Lee SS, Tsai CH, Ho YC, Chang YC. The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas. Oral Oncol 2008; 44: 884-90.
8. Lee SS, Tsai CH, Yang SF, Ho YC, Chang YC. Hypoxia inducible facto-1α expression in areca quid chewing-associated oral squamous cell carcinomas. Oral Dis 2010; 16: 696-701.
9. Whisstock J, Skinner R, Lesk AM. An atlas of serpin conformations. Trends Biochem Sci 1998; 23: 63-7.
10. Morimoto RI, Kline MP, Bimston DN, Cotto JJ. The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones. Essays Biochem 1997; 32: 17-29.
11. Nagai N, Tetuya Y, Hosokawa M, et al. The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47). Gene 1999; 227: 241-8.
12. Hebert C, Norris K, Della Coletta R, Reynolds M, Ordóñez J, Sauk JJ. Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines. J Cell Biochem 1999; 73: 248-58.
13. Clarke EP, Sanwal BD. Cloning of a human collagen-binding protein, and its homology with rat gp46, chick hsp47 and mouse J6 proteins. Biochim Biophys Acta 1992; 1129: 246-8.
14. Hirai K, Kikuchi S, Kurita A, et al. Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach. Anticancer Res 2006; 26: 71-8.
15. Poschmann G, Sitek B, Sipos B, et al. Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium. Mol Cell Proteomics 2009; 8: 1105-16.
16. Maitra A, Iacobuzio-Donahue C, Rahman A, et al. Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. Am J Clin Pathol 2002; 118: 52-9.
17. Araki K, Mikami T, Yoshida T, et al. High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach. Br J Cancer 2009; 101: 492-7.
18. Nikitakis NG, Rivera H, Lopes MA, et al. Immunohistochemical expression of angiogenesis-related markers in oral squamous cell carcinomas with multiple metastatic lymph nodes. Am J Clin Pathol 2003; 119: 574-86.
19. Tsai CH, Yang SF, Lee SS, Chang YC. Augmented heme oxygenase-1 expression in areca quid chewing associated-oral submucous fibrosis. Oral Dis 2009; 15: 281-6.
20. Ollins GJ, Nikitakis N, Norris K, Herbert C, Siavash H, Sauk JJ. The production of the endostatin precursor collagen XVIII in head and neck carcinomas is modulated by CBP2/Hsp47. Anticancer Res 2002; 22: 1977-82.
21. Nagata K, Saga S, Yamada KM. Characterization of a novel transformation-sensitive heat-shock protein (HSP47) that binds to collagen. Biochem Biophys Res Commun 1988; 153: 428-34.
22. Nagata K. Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum. Matrix Biol 1998; 16: 379-86.
23. Shroff B, Smith T, Norris K, Pileggi R, Sauk JJ. Hsp 47 is localized to regions of type I collagen production in developing murine femurs and molars. Connect Tissue Res 1993; 29: 273-86.
24. Natsume T, Koide T, Yokota S, Hirayoshi K, Nagata K. Interactions between collagen-binding stress protein HSP47 and collagen. Analysis of kinetic parameters by surface plasmon resonance biosensor. J Biol Chem 1994; 269: 31224-8.
25. Uehara M, Inokuchi T, Tobita T, Ohba S, Asahina I. Expression of heat shock protein 47 in the fibrous tissue adjacent to mouse tumour subjected to photodynamic therapy. Oral Oncol 2007; 43: 804-10.
26. IARC. Betel-quid and areca-nut chewing. Lyon: International Agency for Research on Cancer, Monographs, 1986; 37: 141-202.
27. Trivedy C, Baldwin D, Warnakulasuriya S, Johnson N, Peters T. Copper content in Areca catechu (betel nut) products and oral submucous fibrosis. Lancet 1997; 17: 349.
28. Nair UJ, Obe G, Friesen M, Goldberg MT, Bartsch H. Role of lime in the generation of reactive oxygen species from betel-quid ingredients. Environ Health Perspect 1992; 98: 203-5.
29. Chen CL, Chi CW, Liu TY. Hydroxyl radical formation and oxidative DNA damage induced by areca quid in vivo. J Toxicol Environ Health A 2002; 65: 327-36.
30. Chang YC, Tai KW, Chou MY, Tseng TH. Synergistic effects of peroxynitrite on arecoline-induced cytotoxicity in human buccal mucosal fibroblasts. Toxicol Lett 2000; 118: 61-8.
31. Gillissen A, Nowak D. Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respir Med 1998; 92: 609-23.
32. Rubinfeld H, Seger R. The ERK cascade: a prototype of MAPK signaling. Mol Biotechnol 2005; 31: 151-74.
33. Chang MC, Wu HL, Lee JJ, et al. The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation. J Biol Chem 2004; 279: 50676-83.
34. Lin SC, Lu SY, Lee SY, Lin CY, Chen CH, Chang KW. Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappa B in oral keratinocytes. Int J Cancer 2005; 116: 526-35.
35. Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296: 1655-7.
36. Tseng YH, Chang CS, Liu TY, Kao SY, Chang KW, Lin SC. Areca nut extract treatment down-regulates involucrin in normal human oral keratinocyte through P13K/AKT activation. Oral Oncol 2007; 43: 670-9.
37. Tsai CH, Chou MY, Chang YC. The upregulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis. J Oral Pathol Med 2003; 32: 146-53.
38. Ni WF, Tsai CH, Yang SF, Chang YC. Elevated expression of NF-κB in oral submucous fibrosis-evidence for NF-κB induction by safrole in human buccal mucosal fibroblasts. Oral Oncol 2007; 43: 557-62.
39. Yang SF, Tsai CH, Chang YC. The upregulation of heat shock protein 47 expression in human buccal fibroblasts stimulated with arecoline. J Oral Pathol Med 2008; 37: 206-10.
40. Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001; 411: 355-65.
41. Ohshima M, Sato M, Ishikawa M, Maeno M, Otsuka K. Physiologic levels of epidermal growth factor in saliva stimulate cell migration of an oral epithelial cell line, HO-1-N-1. Eur J Oral Sci 2002; 110: 130-6.