Targeted downregulation of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase significantly mitigates chondroitin sulfate proteoglycan-mediated inhibition

GLIA

Volumn 59, Issue 6, 2011, Pages 981-996

  Karumbaiah, Lohitash ^a   Anand, Sanjay ^a   Thazhath, Rupal ^b   Zhong, Yinghui ^a   Mckeon, Robert J ^c   Bellamkonda, Ravi V ^a  

^a Emory University   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astroglial scar; Axon regeneration; CNS repair; CS E; Glycosaminoglycan

Indexed keywords

CHONDROITIN SULFATE; GLYCOSAMINOGLYCAN; MESSENGER RNA; N ACETYLGALACTOSAMINE 4 SULFATE 6 O SULFOTRANSFERASE; PROTEOGLYCAN; SMALL INTERFERING RNA; SULFOTRANSFERASE; SULFOTRANSFERASE 11; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN INJURY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EXTRACELLULAR MATRIX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SULFATION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; CHONDROITIN SULFATE PROTEOGLYCANS; DOWN-REGULATION; GENE TARGETING; MALE; NEURAL INHIBITION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SULFOTRANSFERASES;

EID: 79954456797     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21170     Document Type: Article

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