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Volumn 691, Issue , 2011, Pages 487-491

Workshop summary: Introduction to rational design of new means for therapeutic modulation of function of the TNF family

Author keywords

[No Author keywords available]

Indexed keywords

APRIL PROTEIN; ATACICEPT; B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; B CELL MATURATION ANTIGEN; BELIMUMAB; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DENOSUMAB; ETANERCEPT; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 79954451355     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-6612-4_50     Document Type: Conference Paper
Times cited : (8)

References (16)
  • 1
    • 84855456208 scopus 로고    scopus 로고
    • Top 20 Biologics - 2008 Sales of Antibodies & Proteins, La Merie Business Intelligence (article dated March 9, 2009, available at
    • (2008) Top 20 Biologics - 2008 Sales of Antibodies R&D Proteins. In R&D Pipeline News, La Merie Business Intelligence (article dated March 9, 2009, available at www.pipelinereview.com)
    • (2008) R&D Pipeline News
  • 2
    • 63749093322 scopus 로고    scopus 로고
    • Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor
    • Kaymakcalan Z et al (2009) Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor. Clin Immunol 131 (2):308-316
    • (2009) Clin Immunol , vol.131 , Issue.2 , pp. 308-316
    • Kaymakcalan, Z.1
  • 3
    • 68649095916 scopus 로고    scopus 로고
    • Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: Useful information for designing artificial proteo-antagonists
    • Mukai Y et al (2009) Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: Useful information for designing artificial proteo-antagonists. J Biochem 146 (2):167-172
    • (2009) J Biochem , vol.146 , Issue.2 , pp. 167-172
    • Mukai, Y.1
  • 4
    • 62249094525 scopus 로고    scopus 로고
    • Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
    • McAlpine FE et al (2009) Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiol Dis 34 (1): 163-177
    • (2009) Neurobiol Dis , vol.34 , Issue.1 , pp. 163-177
    • McAlpine, F.E.1
  • 5
    • 65549150310 scopus 로고    scopus 로고
    • Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette-Guérin(BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis
    • Olleros ML et al (2009) Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette-Guérin(BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis. J Inf Dis 199 (7):1109-1120
    • (2009) J Inf Dis , vol.199 , Issue.7 , pp. 1109-1120
    • Olleros, M.L.1
  • 6
    • 34548657310 scopus 로고    scopus 로고
    • Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection
    • Zalevsky J et al (2007) Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection. J Immunol 179 (3):1872-1883
    • (2007) J Immunol , vol.179 , Issue.3 , pp. 1872-1883
    • Zalevsky, J.1
  • 7
    • 46449115901 scopus 로고    scopus 로고
    • The exploration of macrocycles for drug discovery-an underexploited structural class
    • Driggers EM et al (2008) The exploration of macrocycles for drug discovery-an underexploited structural class. Nat Rev Drug Discov 7 (7):608-624
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.7 , pp. 608-624
    • Driggers, E.M.1
  • 8
    • 66349091863 scopus 로고    scopus 로고
    • Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-A production in human whole blood
    • Wu J et al (2009) Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-a production in human whole blood. Bioorg Med Chem Lett 19 (13): 3485-3488
    • (2009) Bioorg Med Chem Lett , vol.19 , Issue.13 , pp. 3485-3488
    • Wu, J.1
  • 9
    • 71749092275 scopus 로고    scopus 로고
    • The TNF superfamily in 2009: New pathways, new indications and new drugs
    • Tansey MG, Szymkowski DE (2009) The TNF superfamily in 2009: New pathways, new indications and new drugs. Drug Discov Today 14(23-24):1082-1088
    • (2009) Drug Discov Today , vol.14 , Issue.23-24 , pp. 1082-1088
    • Tansey, M.G.1    Szymkowski, D.E.2
  • 10
    • 34548401627 scopus 로고    scopus 로고
    • Clinical development of anti-RANKL therapy
    • Schwarz EM, Ritchlin CT (2007) Clinical development of anti-RANKL therapy. Arthritis Res Ther 9 Suppl 1, S7
    • (2007) Arthritis Res Ther , vol.9 , Issue.SUPPL. 1
    • Schwarz, E.M.1    Ritchlin, C.T.2
  • 11
    • 59649094164 scopus 로고    scopus 로고
    • Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis
    • Razmara M et al (2009) Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis. Am J Pathol 174 (2):460-474
    • (2009) Am J Pathol , vol.174 , Issue.2 , pp. 460-474
    • Razmara, M.1
  • 12
    • 70449707487 scopus 로고    scopus 로고
    • Improving TNF as a cancer therapeutic: Tailor-made TNF fusion proteins with conserved antitumor activity and reduced systemic side effects
    • Gerspach J et al (2009) Improving TNF as a cancer therapeutic: Tailor-made TNF fusion proteins with conserved antitumor activity and reduced systemic side effects. Biofactors 35 (4):364-372
    • (2009) Biofactors , vol.35 , Issue.4 , pp. 364-372
    • Gerspach, J.1
  • 13
    • 67349126692 scopus 로고    scopus 로고
    • Death ligands designed to kill: Development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands
    • Gerspach J et al (2009) Death ligands designed to kill: Development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands. Results Probl Cell Differ 49:241-273
    • (2009) Results Probl Cell Differ , vol.49 , pp. 241-273
    • Gerspach, J.1
  • 14
    • 63449085835 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model
    • Duiker EW et al (2009) Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model. Clin Cancer Res 15 (6):2048-2057
    • (2009) Clin Cancer Res , vol.15 , Issue.6 , pp. 2048-2057
    • Duiker, E.W.1
  • 15
    • 63549135868 scopus 로고    scopus 로고
    • Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma
    • Labrinidis A et al (2009) Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma. Clin Cancer Res 15 (6):1998-2009
    • (2009) Clin Cancer Res , vol.15 , Issue.6 , pp. 1998-2009
    • Labrinidis, A.1
  • 16
    • 67650444732 scopus 로고    scopus 로고
    • Targeted depletion of lymphotoxin-A-expressing TH1 and TH17 cells inhibits autoimmune disease
    • Chiang EY et al (2009) Targeted depletion of lymphotoxin-a-expressing TH1 and TH17 cells inhibits autoimmune disease. Nat Med 15 (7):766-773
    • (2009) Nat Med , vol.15 , Issue.7 , pp. 766-773
    • Chiang, E.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.