Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): Role of serotonin and involvement of CREB and ERK cascade

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 2, 2011, Pages 169-178

  Di Benedetto, Manuela ^a   Del Carmen Bastías Candia, Sussy ^a   D'addario, Claudio ^a   Porticella, Elena Elettra ^a   Cavina, Chiara ^a   Candeletti, Sanzio ^a   Romualdi, Patrizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Brainstem; CREB; MAP ERK kinases; MDMA; Opioid system

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DYNORPHIN; KAPPA OPIATE RECEPTOR; MESSENGER RNA; METHYSERGIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOCICEPTIN; NOCICEPTIN RECEPTOR; PRODYNORPHIN; PRONOCICEPTIN; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; SEROTONINERGIC SYSTEM;

ANIMALS; BLOTTING, WESTERN; BRAIN STEM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENKEPHALINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; MALE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; OPIOID PEPTIDES; PHOSPHORYLATION; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, KAPPA; RECEPTORS, SEROTONIN, 5-HT1; RECEPTORS, SEROTONIN, 5-HT2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; SEROTONIN ANTAGONISTS; SIGNAL TRANSDUCTION;

EID: 79954445696     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0587-5     Document Type: Article

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