Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein

FEBS Letters

Volumn 585, Issue 8, 2011, Pages 1147-1152

  Okuhira, Keiichiro ^a   Ohoka, Nobumichi ^a   Sai, Kimie ^a   Nishimaki Mogami, Tomoko ^a   Itoh, Yukihiro ^b   Ishikawa, Minoru ^b   Hashimoto, Yuichi ^b   Naito, Mikihiko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cellular inhibitor of apoptosis protein 1; Cellular retinoic acid binding protein II; Proteasome; Protein knockdown; Ubiquitin

Indexed keywords

BESTATIN DERIVATIVE; CELLULAR RETINOL BINDING PROTEIN; CELLULAR RETINOL BINDING PROTEIN 2; HYBRID PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; N [(2,3) 3 AMINO 2 HYDROXY 4 PHENYLBUTYRYL] LEUCINE METHYL ESTER; PROTEIN SNIPER 2; PROTEIN SNIPER 4; RETINOIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TARGETING; STRUCTURE ANALYSIS; UBIQUITINATION;

CELL LINE, TUMOR; CROSS-LINKING REAGENTS; HUMANS; IMMUNOBLOTTING; INHIBITOR OF APOPTOSIS PROTEINS; LEUCINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; RECEPTORS, RETINOIC ACID; RNA INTERFERENCE; TRETINOIN; UBIQUITINATION;

EID: 79954445413     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.03.019     Document Type: Article

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