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Bioorganic and Medicinal Chemistry

Volumn 19, Issue 8, 2011, Pages 2641-2649

Inhibitory properties of 2-substituent-1H-benzimidazole-4-carboxamide derivatives against enteroviruses

(5) Xue, Fei a Luo, Xianjin a Ye, Chenghao a Ye, Weidong b Wang, Yue c

a SHANGHAI JIAO TONG UNIVERSITY (China)

b Zhejiang Medicine Co Ltd (China)

c CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION (China)

Author keywords

Benzimidazole 4 carboxamide; Coxsackie virus A16; Coxsackie virus B3; Coxsackie virus B6; Enterovirus; Enterovirus 71; Picornavirus

Indexed keywords

1H BENZIMIDAZOLE 4 CARBOXAMIDE DERIVATIVE; 2 (2,3,4 TRIMETHOXYPHENYL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (3,4 DIMETHOXYPHENYL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (5 NITROFURAN 2 YL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (5 NITROFURAN 2 YL) N (2 FLUOROPHENYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (FURAN 2 YL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (FURAN 2 YL) N (2 FLUOROPHENYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (FURAN 2 YL) N [2 (4 NITROPHENYL)PENTAN 3 YL] 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (PYRIDIN 2 YL) N (2 FLUOROPHENYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) N (4 METHYLTHIAZOL 2 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) N [2 (4 NITROPHENYL)PENTAN 3 YL] 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) N ETHYLOL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 2 YL) N PHENYL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (PYRIDIN 3 YL) N (2 FLUOROPHENYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) N (4 METHYLTHIAZOL 2 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) N [2 (4 NITROPHENYL)PENTAN 3 YL] 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) N ETHYLOL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 3 YL) N PHENYL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 4 YL) 1H BENZIMIDAZOLE 4 CARBOXYLIC ACID; 2 (PYRIDIN 4 YL) N (2 FLUOROPHENYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 4 YL) N (4 METHYLTHIAZOL 2 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 4 YL) N [2 (4 NITROPHENYL)PENTAN 3 YL] 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 4 YL) N ETHYLOL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2 (PYRIDIN 4 YL) N PHENYL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; ANTIVIRUS AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS; COXSACKIE VIRUS A16; COXSACKIE VIRUS B3; COXSACKIE VIRUS B6; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROVIRUS; ENTEROVIRUS 71; IC 50; IN VITRO STUDY; NONHUMAN; VERO CELL; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; BENZIMIDAZOLES; CERCOPITHECUS AETHIOPS; DRUG DESIGN; ENTEROVIRUS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

COXSACKIEVIRUS; ENTEROVIRUS; HUMAN ENTEROVIRUS 71; PICORNAVIRIDAE;

EID: 79954423680 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2011.03.007 Document Type: Article

Times cited : (42)

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