Assessment of the effect of surgery on the kinetics of circulating tumour cells in patients with operable breast cancer based on cytokeratin-19 mRNA detection

European Journal of Surgical Oncology

Volumn 37, Issue 5, 2011, Pages 404-410

  Daskalakis, M ^a   Mavroudis, D ^a,b   Sanidas, E ^a   Apostolaki, S ^b   Askoxylakis, I ^a   De Bree, E ^a   Georgoulias, V ^a,b   Melissas, J ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

Breast cancer; Circulating tumour cells; Cytokeratin 19; Micrometastatic disease

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOKERATIN 19; MESSENGER RNA;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BREAST CANCER; BREAST LESION; BREAST SURGERY; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; HUMAN; LYMPH NODE DISSECTION; MAJOR CLINICAL STUDY; MASTECTOMY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RNA ANALYSIS; TUMOR CELL; WIDE EXCISION;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; KERATIN-19; KINETICS; MIDDLE AGED; NEOPLASTIC CELLS, CIRCULATING; PROGNOSIS; RESEARCH DESIGN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 79954420045     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2011.02.003     Document Type: Article

References (30)

1. Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials Lancet 365 2005 1687 1717
2. M. Cristofanilli, and J. Mendelsohn Circulating tumor cells in breast cancer: advanced tools for ''tailored'' therapy? Proc Natl Acad Sci U S A 103 2006 17073 17074 (Pubitemid 44788923)
3. C. Alix-Panabires, S. Riethdorf, and K. Pantel Circulating tumor cells and bone marrow micrometastasis Clin Cancer Res 14 2008 5013 5021
4. M. Galán, N. Viñolas, and D. Colomer Detection of occult breast cancer cells by amplification of CK19 mRNA by reverse transcriptase-polymerase chain reaction: role of surgical manipulation Anticancer Res 22 2002 2877 2884 (Pubitemid 36069328)
5. X.C. Hu, W.T. Loo, and L.W. Chow Surgery-related shedding of breast cancer cells as determined by RT-PCR assay J Surg Oncol 82 2003 228 232 (Pubitemid 36389914)
6. M.S. Ismail, W. Wynendaele, and J.L. Aerts Detection of micrometastatic disease and monitoring of perioperative tumor cell dissemination in primary operable breast cancer patients using real-time quantitative reverse transcription-PCR Clin Cancer Res 10 2004 196 201 (Pubitemid 38114180)
7. O. Camara, A. Kavallaris, H. Nöschel, M. Rengsberger, C. Jörke, and K. Pachmann Seeding of epithelial cells into circulation during surgery for breast cancer: the fate of malignant and benign mobilized cells World J Surg Oncol 4 2006 67
8. S. Braun, K. Pantel, and P. Muller Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer N Engl J Med 342 2000 525 533 (Pubitemid 30117892)
9. A.E. Ring, L. Zabaglo, M.G. Ormerod, I.E. Smith, and M. Dowsett Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques Br J Cancer 92 2005 906 912 (Pubitemid 40462638)
10. M.M. Reinholz, A. Nibbe, and L.M. Jonart Evaluation of a panel of tumor markers for molecular detection of circulating cancer cells in women with suspected breast cancer Clin Cancer Res 11 2005 3722 3732 (Pubitemid 40685589)
11. A. Schoenfeld, K.H. Kruger, and J. Gomm The detection of micrometastases in the peripheral blood and bone marrow of patients with breast cancer using immunohistochemistry and reverse transcriptase polymerase chain reaction for keratin 19 Eur J Cancer 33 1997 854 861 (Pubitemid 27287035)
12. A. Stathopoulou, I. Vlachonikolis, and D. Mavroudis Molecular detection of cytokeratin-19-positive cells in the peripheral blood of patients with operable breast cancer: evaluation of their prognostic significance J Clin Oncol 20 2002 3404 3412
13. A. Stathopoulou, A. Gizi, and M. Perraki Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system Clin Cancer Res 9 2003 5145 5151 (Pubitemid 37413564)
14. C.P. Schröder, M.H. Ruiters, and S. de Jong Detection of micrometastatic breast cancer by means of real time quantitative RT-PCR and immunostaining in perioperative blood samples and sentinel nodes Int J Cancer 106 2003 611 618 (Pubitemid 36966222)
15. N. Xenidis, M. Perraki, and M. Kafousi Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patients J Clin Oncol 24 2006 3756 3762 (Pubitemid 46622314)
16. M. Ignatiadis, G. Kallergi, and M. Ntoulia Prognostic value of the molecular detection of circulating tumor cells using a multimarker reverse transcription-PCR assay for cytokeratin 19, mammaglobin A, and HER2 in early breast cancer Clin Cancer Res 14 2008 2593 2600
17. K. Dowlatshahi, M. Fan, H.C. Snider, and F.A. Habib Lymph node micrometastases from breast carcinoma: reviewing the dilemma Cancer 80 1997 1188 1197 (Pubitemid 27407219)
18. K. Pantel, R.H. Brakenhoff, and B. Brandt Detection, clinical relevance and specific biological properties of disseminating tumour cells Nat Rev Cancer 8 2008 329 340 (Pubitemid 351596394)
19. J.A. Aguirre-Ghiso Models, mechanisms and clinical evidence for cancer dormancy Nat Rev Cancer 7 2007 834 846 (Pubitemid 350006258)
20. R. Demicheli, M.W. Retsky, W.J. Hrushesky, and M. Baum Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures Nat Clin Pract Oncol 4 2007 699 710 (Pubitemid 350187005)
21. F. Gao, S.B. Tan, D. Machin, and N.S. Wong Confirmation of double-peaked time distribution of mortality among Asian breast cancer patients in a population-based study Breast Cancer Res 9 2007 R21
22. R. Demicheli, P. Valagussa, and G. Bonadonna Does surgery modify growth kinetics of breast cancer micrometastases? Br J Cancer 85 2001 490 492 (Pubitemid 32808269)
23. M. Retsky, G. Bonadonna, R. Demicheli, J. Folkman, W. Hrushesky, and P. Valagussa Hypothesis: induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients Breast Cancer Res 6 2004 R372 R374
24. G. Méhes, A. Witt, E. Kubista, and P.F. Ambros Circulating breast cancer cells are frequently apoptotic Am J Pathol 159 2001 17 20 (Pubitemid 33704186)
25. E. Ruoslahti, and J.C. Reed Anchorage dependence, integrins, and apoptosis Cell 7 1994 477 478 (Pubitemid 24153987)
26. S.M. Frisch, and H. Francis Disruption of epithelial cell-matrix interactions induces apoptosis J Cell Biol 124 1994 619 626 (Pubitemid 24064472)
27. C.W. Wong, A. Lee, and L. Shientag Apoptosis: an early event in metastatic inefficiency Cancer Res 61 2001 333 338 (Pubitemid 32095735)
28. L. Zhang, S. Kharbanda, S.W. McLeskey, and F.G. Kern Overexpression of fibroblast growth factor 1 in MCF-7 breast cancer cells facilitates tumor cell dissemination but does not support the development of macrometastases in the lungs or lymph nodes Cancer Res 59 1999 5023 5029 (Pubitemid 29472910)
29. J.S. Palumbo, J.M. Potter, L.S. Kaplan, K. Talmage, D.G. Jackson, and J.L. Degen Spontaneous hematogenous and lymphatic metastasis, but not primary tumor growth or angiogenesis, is diminished in fibrinogen-deficient mice Cancer Res 62 2002 6966 6972 (Pubitemid 35424088)
30. G. Curigliano, J.Y. Petit, and F. Bertolini Systemic effects of surgery: quantitative analysis of circulating basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta) in patients with breast cancer who underwent limited or extended surgery Breast Cancer Res Treat 93 2005 35 40 (Pubitemid 41355988)