-
1
-
-
84944073735
-
Peptidyl-dipeptidase A/angiotensin 1-converting enzyme
-
edn 2 A.J. Barrett, N.D. Rawling, J.F. Woessner, Academic Press San Diego.
-
P. Corvol, M. Eyries, and F. Soubrier Peptidyl-dipeptidase A/angiotensin 1-converting enzyme edn 2 A.J. Barrett, N.D. Rawling, J.F. Woessner, Handbook of Proteolytic Enzymes vol 1 2004 Academic Press San Diego 332 346
-
(2004)
Handbook of Proteolytic Enzymes
, vol.1
, pp. 332-346
-
-
Corvol, P.1
Eyries, M.2
Soubrier, F.3
-
2
-
-
75149132682
-
Misdiagnosis and mistreatment of a common side-effect - Angiotensin-converting enzyme inhibitor-induced cough
-
S. Vegter, and L.T. de Jong-van den Berg Misdiagnosis and mistreatment of a common side-effect - angiotensin-converting enzyme inhibitor-induced cough Br J Clin Pharmacol 69 2010 200 203
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 200-203
-
-
Vegter, S.1
De Jong-Van Den Berg, L.T.2
-
3
-
-
0025739667
-
The two homologous Domains of human angiotensin I-converting enzyme are both catalytically active
-
L. Wei, F. Alhenc-Gelas, P. Corvol, and E. Clauser The two homologous domains of human angiotensin I-converting enzyme are both catalytically active J Biol Chem 266 1991 9002 9008 (Pubitemid 21906610)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.14
, pp. 9002-9008
-
-
Wei, L.1
Alhenc-Gelas, F.2
Corvol, P.3
Clauser, E.4
-
4
-
-
77249086632
-
Angiotensin-converting enzyme: A protein conserved during evolution
-
G. Riviere Angiotensin-converting enzyme: a protein conserved during evolution J Soc Biol 203 2009 281 293 This is an excellent review of the evolution of ACE. The ancestral form and function of ACE is discussed.
-
(2009)
J Soc Biol
, vol.203
, pp. 281-293
-
-
Riviere, G.1
-
5
-
-
0025824349
-
Structure of the angiotensin I-converting enzyme gene: Two alternate promoters correspond to evolutionary steps of a duplicated gene
-
C. Hubert, A.M. Houot, P. Corvol, and F. Soubrier Structure of the angiotensin I-converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene J Biol Chem 266 1991 15377 15383 (Pubitemid 21907658)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.23
, pp. 15377-15383
-
-
Hubert, C.1
Houot, A.-M.2
Corvol, P.3
Soubrier, F.4
-
6
-
-
0029060861
-
Male-female differences in fertility and blood pressure in ACE-deficient mice
-
J.H. Krege, S.W. John, L.L. Langenbach, J.B. Hodgin, J.R. Hagaman, E.S. Bachman, J.C. Jennette, D.A. O'Brien, and O. Smithies Male-female differences in fertility and blood pressure in ACE-deficient mice Nature 375 1995 146 148
-
(1995)
Nature
, vol.375
, pp. 146-148
-
-
Krege, J.H.1
John, S.W.2
Langenbach, L.L.3
Hodgin, J.B.4
Hagaman, J.R.5
Bachman, E.S.6
Jennette, J.C.7
O'Brien, D.A.8
Smithies, O.9
-
7
-
-
1842292171
-
The critical role of tissue angiotensin-converting enzyme as revealed by genetargeting in mice
-
C.R. Esther, E.M. Marino, T.E. Howard, A. Michaud, P. Corvol, M.R. Capecchi, and K.E. Bernstein The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice J Clin Invest 99 1997 2375 2385 (Pubitemid 27227714)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.10
, pp. 2375-2385
-
-
Esther Jr., C.R.1
Marino, E.M.2
Howard, T.E.3
Machaud, A.4
Corvol, P.5
Capecchi, M.R.6
Bernstein, K.E.7
-
8
-
-
30744444163
-
Male fertility is dependent on dipeptidase activity of testis ACE [5]
-
DOI 10.1038/nm1105-1140, PII NM11051140
-
S. Fuchs, K. Frenzel, C. Hubert, R. Lyng, L. Muller, A. Michaud, H.D. Xiao, J.W. Adams, M.R. Capecchi, and P. Corvol Male fertility is dependent on dipeptidase activity of testis ACE Nat Med 11 2005 1140 1142 This manuscript demonstrates the crucial importance of the catalytic activity of the testis isoform of ACE in male fertility. It also links sperm-egg binding with ACE enzymatic activity. (Pubitemid 43093652)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1140-1142
-
-
Fuchs, S.1
Frenzel, K.2
Hubert, C.3
Lyng, R.4
Muller, L.5
Michaud, A.6
Xiao, H.D.7
Adams, J.W.8
Capecchi, M.R.9
Corvol, P.10
Shur, B.D.11
Bernstein, K.E.12
-
9
-
-
0025284828
-
Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene
-
T.E. Howard, S.Y. Shai, K.G. Langford, B.M. Martin, and K.E. Bernstein Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene Mol Cell Biol 10 1990 4294 4302
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4294-4302
-
-
Howard, T.E.1
Shai, S.Y.2
Langford, K.G.3
Martin, B.M.4
Bernstein, K.E.5
-
10
-
-
0025941552
-
Transgenic mice demonstrate a testis-specific promoter for angiotensin- converting enzyme
-
K.G. Langford, S.Y. Shai, T.E. Howard, M.J. Kovac, P.A. Overbeek, and K.E. Bernstein Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme J Biol Chem 266 1991 15559 15562 (Pubitemid 21907686)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.24
, pp. 15559-15562
-
-
Langford, K.G.1
Shai, S.-Y.2
Howard, T.E.3
Kovac, M.J.4
Overbeek, P.A.5
Bernstein, K.E.6
-
11
-
-
2442530754
-
Zinc-metalloproteases in insects: ACE and ECE
-
DOI 10.1016/j.ibmb.2004.03.007, PII S0965174804000402
-
N. Macours, and K. Hens Zinc-metalloproteases in insects: ACE and ECE Insect Biochem Mol Biol 34 2004 501 510 (Pubitemid 38629896)
-
(2004)
Insect Biochemistry and Molecular Biology
, vol.34
, Issue.6
, pp. 501-510
-
-
Macours, N.1
Hens, K.2
-
12
-
-
0034254520
-
Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme
-
DOI 10.1021/bi000593q
-
D. Coates, R.E. Isaac, J. Cotton, R. Siviter, T.A. Williams, A. Shirras, P. Corvol, and V. Dive Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme Biochemistry 39 2000 8963 8969 (Pubitemid 30602807)
-
(2000)
Biochemistry
, vol.39
, Issue.30
, pp. 8963-8969
-
-
Coates, D.1
Isaac, R.E.2
Cotton, J.3
Siviter, R.4
Williams, T.A.5
Shirras, A.6
Corvol, P.7
Dive, V.8
-
13
-
-
0029008621
-
Cloning and expression of an evolutionary conserved single-domain angiotensin converting enzyme from Drosophila melanogaster
-
M.J. Cornell, T.A. Williams, N.S. Lamango, D. Coates, P. Corvol, F. Soubrier, J. Hoheisel, H. Lehrach, and R.E. Isaac Cloning and expression of an evolutionary conserved single-domain angiotensin converting enzyme from Drosophila melanogaster J Biol Chem 270 1995 13613 13619
-
(1995)
J Biol Chem
, vol.270
, pp. 13613-13619
-
-
Cornell, M.J.1
Williams, T.A.2
Lamango, N.S.3
Coates, D.4
Corvol, P.5
Soubrier, F.6
Hoheisel, J.7
Lehrach, H.8
Isaac, R.E.9
-
14
-
-
0032213594
-
The Drosophila melanogaster-related angiotensin-I-converting enzymes acer and ance - Distinct enzymic characteristics and alternative expression during pupal development
-
X. Houard, T.A. Williams, A. Michaud, P. Dani, R.E. Isaac, A.D. Shirras, D. Coates, and P. Corvol The Drosophila melanogaster-related angiotensin-I-converting enzymes Acer and Ance - distinct enzymic characteristics and alternative expression during pupal development Eur J Biochem 257 1998 599 606 (Pubitemid 28512128)
-
(1998)
European Journal of Biochemistry
, vol.257
, Issue.3
, pp. 599-606
-
-
Houard, X.1
Williams, T.A.2
Michaud, A.3
Dani, P.4
Isaacs, R.E.5
Shirras, A.D.6
Coates, D.7
Corvol, P.8
-
15
-
-
33645028486
-
Structural diversity of angiotensin-converting enzyme
-
R.J. Bingham, V. Dive, S.E. Phillips, A.D. Shirras, and R.E. Isaac Structural diversity of angiotensin-converting enzyme FEBS J 273 2006 362 373
-
(2006)
FEBS J
, vol.273
, pp. 362-373
-
-
Bingham, R.J.1
Dive, V.2
Phillips, S.E.3
Shirras, A.D.4
Isaac, R.E.5
-
16
-
-
77955269958
-
Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster
-
M. Akif, I. Ntai, E.D. Sturrock, R.E. Isaac, B.O. Bachmann, and K.R. Acharya Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster Biochem Biophys Res Commun 398 2010 532 536
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 532-536
-
-
Akif, M.1
Ntai, I.2
Sturrock, E.D.3
Isaac, R.E.4
Bachmann, B.O.5
Acharya, K.R.6
-
17
-
-
0028967315
-
The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme
-
A. Rousseau, A. Michaud, M.T. Chauvet, M. Lenfant, and P. Corvol The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme J Biol Chem 270 1995 3656 3661
-
(1995)
J Biol Chem
, vol.270
, pp. 3656-3661
-
-
Rousseau, A.1
Michaud, A.2
Chauvet, M.T.3
Lenfant, M.4
Corvol, P.5
-
18
-
-
0031954590
-
N-domain-specific substrate and c-domain inhibitors of angiotensin- converting enzyme angiotensin-(1-7) and keto-ace
-
P.A. Deddish, B. Marcic, H.L. Jackman, H.Z. Wang, R.A. Skidgel, and E.G. Erdos N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE Hypertension 31 1998 912 917 (Pubitemid 28185567)
-
(1998)
Hypertension
, vol.31
, Issue.4
, pp. 912-917
-
-
Deddish, P.A.1
Marcic, B.2
Jackman, H.L.3
Wang, H.-Z.4
Skidgel, R.A.5
Erdos, E.G.6
-
19
-
-
70450257558
-
Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
-
K. Zou, T. Maeda, A. Watanabe, J. Liu, S. Liu, R. Oba, Y. Satoh, H. Komano, and M. Michikawa Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme J Biol Chem 284 2009 31914 31920 This study shows that the amyloid-β protein 1-42 is a substrate of the N-terminal site of ACE, suggesting that ACE inhibitors may influence the development of Alzheimer's disease.
-
(2009)
J Biol Chem
, vol.284
, pp. 31914-31920
-
-
Zou, K.1
Maeda, T.2
Watanabe, A.3
Liu, J.4
Liu, S.5
Oba, R.6
Satoh, Y.7
Komano, H.8
Michikawa, M.9
-
20
-
-
13044297058
-
RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites
-
DOI 10.1073/pnas.96.8.4330
-
V. Dive, J. Cotton, A. Yiotakis, A. Michaud, S. Vassiliou, J. Jiracek, G. Vazeux, M.T. Chauvet, and P. Cuniasse Corvol P: RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites Proc Natl Acad Sci U S A 96 1999 4330 4335 (Pubitemid 29190336)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.8
, pp. 4330-4335
-
-
Dive, V.1
Cotton, J.2
Yiotakis, A.3
Michaud, A.4
Vassiliou, S.5
Jiracek, J.6
Vazeux, G.7
Chauvet, M.-T.8
Cuniasse, P.9
Corvol, P.10
-
21
-
-
0035042245
-
RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis
-
C. Junot, M.F. Gonzales, E. Ezan, J. Cotton, G. Vazeux, A. Michaud, M. Azizi, S. Vassiliou, A. Yiotakis, and P. Corvol RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis J Pharmacol Exp Ther 297 2001 606 611 (Pubitemid 32377991)
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.297
, Issue.2
, pp. 606-611
-
-
Junot, C.1
Gonzales, M.-F.2
Ezan, E.3
Cotton, J.4
Vazeux, G.5
Michaud, A.6
Azizi, M.7
Vassiliou, S.8
Yiotakis, A.9
Corvol, P.10
Dive, V.11
-
22
-
-
0042490795
-
Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin insights from selective inhibitors
-
DOI 10.1161/01.RES.0000081593.33848.FC
-
D. Georgiadis, F. Beau, B. Czarny, J. Cotton, A. Yiotakis, and V. Dive Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin: insights from selective inhibitors Circ Res 93 2003 148 154 (Pubitemid 36919702)
-
(2003)
Circulation Research
, vol.93
, Issue.2
, pp. 148-154
-
-
Georgiadis, D.1
Beau, F.2
Czarny, B.3
Cotton, J.4
Yiotakis, A.5
Dive, V.6
-
23
-
-
44449140132
-
Probing the basis of domain-dependent inhibition using novel ketone inhibitors of angiotensin-converting enzyme
-
DOI 10.1021/bi8002605
-
J.M. Watermeyer, W.L. Kroger, H.G. O'Neill, B.T. Sewell, and E.D. Sturrock Probing the basis of domain-dependent inhibition using novel ketone inhibitors of angiotensin-converting enzyme Biochemistry 47 2008 5942 5950 (Pubitemid 351770024)
-
(2008)
Biochemistry
, vol.47
, Issue.22
, pp. 5942-5950
-
-
Watermeyer, J.M.1
Kroger, W.L.2
O'Neill, H.G.3
Sewell, B.T.4
Sturrock, E.D.5
-
24
-
-
77953461949
-
Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril
-
J.M. Watermeyer, W.L. Kroger, H.G. O'Neill, B.T. Sewell, and E.D. Sturrock Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril Biochem J 428 2010 67 74 On the basis of X-ray crystallography analyses, the authors show that a chemical modification of the non-specific ACE inhibitor lisinopril can transform it into a highly C-terminal-specific ACE inhibitor.
-
(2010)
Biochem J
, vol.428
, pp. 67-74
-
-
Watermeyer, J.M.1
Kroger, W.L.2
O'Neill, H.G.3
Sewell, B.T.4
Sturrock, E.D.5
-
25
-
-
0028095670
-
Targeted gene replacement
-
M.R. Capecchi Targeted gene replacement Sci Am 270 1994 52 59
-
(1994)
Sci Am
, vol.270
, pp. 52-59
-
-
Capecchi, M.R.1
-
26
-
-
0029925360
-
Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility
-
C.R. Esther Jr., T.E. Howard, E.M. Marino, J.M. Goddard, M.R. Capecchi, and K.E. Bernstein Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility Lab Invest 74 1996 953 965 (Pubitemid 26152664)
-
(1996)
Laboratory Investigation
, vol.74
, Issue.5
, pp. 953-965
-
-
Esther Jr., C.R.1
Howard, T.E.2
Marino, E.M.3
Goddard, J.M.4
Capecchi, M.R.5
Bernstein, K.E.6
-
27
-
-
0027532257
-
Location of crossovers during gene targeting with insertion and replacement vectors
-
C. Deng, K.R. Thomas, and M.R. Capecchi Location of crossovers during gene targeting with insertion and replacement vectors Mol Cell Biol 13 1993 2134 2140 (Pubitemid 23097692)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.4
, pp. 2134-2140
-
-
Deng, C.1
Thomas, K.R.2
Capecchi, M.R.3
-
28
-
-
11144355163
-
Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice
-
DOI 10.1074/jbc.M400149200
-
S. Fuchs, H.D. Xiao, J.M. Cole, J.W. Adams, K. Frenzel, A. Michaud, H. Zhao, G. Keshelava, M.R. Capecchi, and P. Corvol Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice J Biol Chem 279 2004 15946 15953 This paper shows that the selective inactivation of the N-terminal site of ACE in vivo has no effect on blood pressure; the presence of the C-terminal ACE catalytic domain is sufficient to maintain a functional renin-angiotensin system. It also strongly suggests that the anemia present in ACE null mice is not due to the accumulation of the tetrapeptide AcSDKP. (Pubitemid 38509282)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.16
, pp. 15946-15953
-
-
Fuchs, S.1
Xiao, H.D.2
Cole, J.M.3
Adams, J.W.4
Frenzel, K.5
Michaud, A.6
Zhao, H.7
Keshelava, G.8
Capecchi, M.R.9
Corvol, P.10
Bernstein, K.E.11
-
29
-
-
38549119426
-
Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo
-
DOI 10.1161/HYPERTENSIONAHA.107.097865, PII 0000426820080200000019
-
S. Fuchs, H.D. Xiao, C. Hubert, A. Michaud, D.J. Campbell, J.W. Adams, M.R. Capecchi, P. Corvol, and K.E. Bernstein Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo Hypertension 51 2008 267 274 This study shows that the C-domain of ACE is the predominant site of angiotensin I cleavage in vivo. (Pubitemid 351159938)
-
(2008)
Hypertension
, vol.51
, Issue.2
, pp. 267-274
-
-
Fuchs, S.1
Xiao, H.D.2
Hubert, C.3
Michaud, A.4
Campbell, D.J.5
Adams, J.W.6
Capecchi, M.R.7
Corvol, P.8
Bernstein, K.E.9
-
30
-
-
0037059464
-
Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure
-
DOI 10.1161/hh0102.102360
-
J. Cole, L. Quach du, K. Sundaram, P. Corvol, M.R. Capecchi, and K.E. Bernstein Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure Circ Res 90 2002 87 92 (Pubitemid 34074613)
-
(2002)
Circulation Research
, vol.90
, Issue.1
, pp. 87-92
-
-
Cole, J.1
Quach, D.L.2
Sundaram, K.3
Corvol, P.4
Capecchi, M.R.5
Bernstein, K.E.6
-
31
-
-
0031037629
-
Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis
-
J.H. Krege, H.S. Kim, J.S. Moyer, J.C. Jennette, L. Peng, S.K. Hiller, and O. Smithies Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis Hypertension 29 1997 150 157 (Pubitemid 27074036)
-
(1997)
Hypertension
, vol.29
, Issue.1 II
, pp. 150-157
-
-
Krege, J.H.1
Kim, H.-S.2
Moyer, J.S.3
Jennette, J.C.4
Peng, L.5
Hiller, S.K.6
Smithies, O.7
-
32
-
-
0031297091
-
Theodore Cooper Memorial Lecture. A mouse view of hypertension
-
O. Smithies Theodore Cooper Memorial Lecture. A mouse view of hypertension Hypertension 30 1997 1318 1324
-
(1997)
Hypertension
, vol.30
, pp. 1318-1324
-
-
Smithies, O.1
-
33
-
-
0030698849
-
High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: A new marker of chronic angiotensin-converting enzyme inhibition
-
M. Azizi, E. Ezan, L. Nicolet, J.M. Grognet, and J. Menard High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition Hypertension 30 1997 1015 1019 (Pubitemid 27476151)
-
(1997)
Hypertension
, vol.30
, Issue.5
, pp. 1015-1019
-
-
Azizi, M.1
Ezan, E.2
Nicolet, L.3
Grognet, J.-M.4
Menard, J.5
-
34
-
-
0030027331
-
Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline
-
M. Azizi, A. Rousseau, E. Ezan, T.T. Guyene, S. Michelet, J.M. Grognet, M. Lenfant, P. Corvol, and J. Menard Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline J Clin Invest 97 1996 839 844 (Pubitemid 26060543)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.3
, pp. 839-844
-
-
Azizi, M.1
Rousseau, A.2
Ezan, E.3
Guyene, T.-T.4
Michelet, S.5
Grognet, J.-M.6
Lenfant, M.7
Corvol, P.8
Menard, J.9
-
35
-
-
0026475680
-
Reversible inhibitory effects and absence of toxicity of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in human long-term bone marrow culture
-
D. Bonnet, F.M. Lemoine, E. Khoury, P. Pradelles, A. Najman, and M. Guigon Reversible inhibitory effects and absence of toxicity of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in human long-term bone marrow culture Exp Hematol 20 1992 1165 1169
-
(1992)
Exp Hematol
, vol.20
, pp. 1165-1169
-
-
Bonnet, D.1
Lemoine, F.M.2
Khoury, E.3
Pradelles, P.4
Najman, A.5
Guigon, M.6
-
36
-
-
0346848845
-
Ac-SDKP Reverses Cardiac Fibrosis in Rats with Renovascular Hypertension
-
DOI 10.1161/01.HYP.0000100423.24330.96
-
H. Peng, O.A. Carretero, D.R. Brigstock, N. Oja-Tebbe, and N.E. Rhaleb Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertension Hypertension 42 2003 1164 1170 The authors show that in hypertension, Ac-SDKP reverses cardiac fibrosis, due in part to a decrease in TGF-β and CTGF in the heart. (Pubitemid 37549072)
-
(2003)
Hypertension
, vol.42
, Issue.6
, pp. 1164-1170
-
-
Peng, H.1
Carretero, O.A.2
Brigstock, D.R.3
Oja-Tebbe, N.4
Rhaleb, N.-E.5
-
37
-
-
54049120719
-
Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension
-
C.X. Lin, N.E. Rhaleb, X.P. Yang, T.D. Liao, M.A. D'Ambrosio, and O.A. Carretero Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension Am J Physiol Heart Circ Physiol 295 2008 H1253 H1261 This manuscript shows that, in angiotensin II-induced hypertension, Ac-SDKP prevents the development of aortic fibrosis.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Lin, C.X.1
Rhaleb, N.E.2
Yang, X.P.3
Liao, T.D.4
D'Ambrosio, M.A.5
Carretero, O.A.6
-
38
-
-
74949132319
-
N-acetyl-seryl-aspartyl-lysyl-proline attenuates renal injury and dysfunction in hypertensive rats with reduced renal mass: Council for high blood pressure research
-
T.D. Liao, X.P. Yang, M. D'Ambrosio, Y. Zhang, N.E. Rhaleb, and O.A. Carretero N-acetyl-seryl-aspartyl-lysyl-proline attenuates renal injury and dysfunction in hypertensive rats with reduced renal mass: council for high blood pressure research Hypertension 55 2010 459 467
-
(2010)
Hypertension
, vol.55
, pp. 459-467
-
-
Liao, T.D.1
Yang, X.P.2
D'Ambrosio, M.3
Zhang, Y.4
Rhaleb, N.E.5
Carretero, O.A.6
-
39
-
-
77956524295
-
Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury
-
P. Li, H.D. Xiao, J. Xu, F.S. Ong, M. Kwon, J. Roman, A. Gal, K.E. Bernstein, and S. Fuchs Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury Am J Pathol 177 2010 1113 1121 This study shows that the inactivation of the N-terminal catalytic site of ACE significantly reduced bleomycin-induced lung fibrosis and implicates AcSDKP in the mechanism of protection.
-
(2010)
Am J Pathol
, vol.177
, pp. 1113-1121
-
-
Li, P.1
Xiao, H.D.2
Xu, J.3
Ong, F.S.4
Kwon, M.5
Roman, J.6
Gal, A.7
Bernstein, K.E.8
Fuchs, S.9
-
40
-
-
39149103740
-
The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?
-
DOI 10.1016/j.biocel.2007.08.011, PII S1357272507002877
-
A. Moeller, K. Ask, D. Warburton, J. Gauldie, and M. Kolb The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int J Biochem Cell Biol 40 2008 362 382 (Pubitemid 351249887)
-
(2008)
International Journal of Biochemistry and Cell Biology
, vol.40
, Issue.3
, pp. 362-382
-
-
Moeller, A.1
Ask, K.2
Warburton, D.3
Gauldie, J.4
Kolb, M.5
-
41
-
-
0036667985
-
Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice
-
C.K. Haston, M. Wang, R.E. Dejournett, X. Zhou, D. Ni, X. Gu, T.M. King, M.M. Weil, R.A. Newman, and C.I. Amos Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice Hum Mol Genet 11 2002 1855 1863
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1855-1863
-
-
Haston, C.K.1
Wang, M.2
Dejournett, R.E.3
Zhou, X.4
Ni, D.5
Gu, X.6
King, T.M.7
Weil, M.M.8
Newman, R.A.9
Amos, C.I.10
-
42
-
-
0033590994
-
S 17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase
-
DOI 10.1006/bbrc.1999.0366
-
H. Barelli, A. Petit, E. Hirsch, S. Wilk, G. De Nanteuil, P. Morain, and F. Checler S 17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase Biochem Biophys Res Commun 257 1999 657 661 (Pubitemid 29301498)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.257
, Issue.3
, pp. 657-661
-
-
Barelli, H.1
Petit, A.2
Hirsch, E.3
Wilk, S.4
De Nanteuil, G.5
Morain, P.6
Checler, F.7
-
43
-
-
41949135032
-
Structure, function and biological relevance of prolyl oligopeptidase
-
Z. Szeltner, and L. Polgar Structure, function and biological relevance of prolyl oligopeptidase Curr Protein Pept Sci 9 2008 96 107
-
(2008)
Curr Protein Pept Sci
, vol.9
, pp. 96-107
-
-
Szeltner, Z.1
Polgar, L.2
-
44
-
-
34250803343
-
Decreased endogenous levels of Ac-SDKP promote organ fibrosis
-
DOI 10.1161/HYPERTENSIONAHA.106.084103, PII 0000426820070700000023
-
M.A. Cavasin, T.D. Liao, X.P. Yang, J.J. Yang, and O.A. Carretero Decreased endogenous levels of Ac-SDKP promote organ fibrosis Hypertension 50 2007 130 136 (Pubitemid 46986021)
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 130-136
-
-
Cavasin, M.A.1
Liao, T.-D.2
Yang, X.-P.3
Yang, J.J.4
Carretero, O.A.5
-
45
-
-
0032478121
-
Angiotensin-converting enzyme and male fertility
-
DOI 10.1073/pnas.95.5.2552
-
J.R. Hagaman, J.S. Moyer, E.S. Bachman, M. Sibony, P.L. Magyar, J.E. Welch, O. Smithies, J.H. Krege, and D.A. O'Brien Angiotensin-converting enzyme and male fertility Proc Natl Acad Sci U S A 95 1998 2552 2557 (Pubitemid 28145980)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.5
, pp. 2552-2557
-
-
Hagaman, J.R.1
Moyer, J.S.2
Bachman, E.S.3
Sibony, M.4
Magyar, P.L.5
Welch, J.E.6
Smithies, O.7
Krege, J.H.8
O'Brien, D.A.9
-
46
-
-
0032527628
-
Selective restoration of male fertility in mice lacking angiotensin- converting enzymes by sperm-specific expression of the testicular isozyme
-
P. Ramaraj, S.P. Kessler, C. Colmenares, and G.C. Sen Selective restoration of male fertility in mice lacking angiotensin-converting enzymes by sperm-specific expression of the testicular isozyme J Clin Invest 102 1998 371 378 (Pubitemid 28335196)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.2
, pp. 371-378
-
-
Ramaraj, P.1
Kessler, S.P.2
Colmenares, C.3
Sen, G.C.4
-
47
-
-
0042908657
-
Molecular cloning of human testicular angiotensin-converting enzyme: The testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme
-
M.R. Ehlers, E.A. Fox, D.J. Strydom, and J.F. Riordan Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme Proc Natl Acad Sci U S A 86 1989 7741 7745 (Pubitemid 19265263)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.20
, pp. 7741-7745
-
-
Ehlers, M.R.W.1
Fox, E.A.2
Strydom, D.J.3
Riordan, J.F.4
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