A framework for understanding experiential deficits in schizophrenia

Psychiatry Research

Volumn 178, Issue 1, 2010, Pages 10-16

  Cohen, Alex S ^a   Minor, Kyle S ^a   Najolia, Gina M ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Affect; Ambivalence; Apathy; Deficit; Emotion; Negative; Positive; Schizophrenia

Indexed keywords

AFFECT; AMBIVALENCE; ANHEDONIA; APATHY; EMOTION; EMOTIONAL DISORDER; HUMAN; NEGATIVE SYNDROME; POSITIVE SYNDROME; PRIORITY JOURNAL; PSYCHOSIS; REVIEW; SCHIZOPHRENIA; SOCIAL DISABILITY; SYMPTOMATOLOGY;

EID: 79954415738     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2009.11.016     Document Type: Review

References (98)

1. Addington, J., Addington, D., 2000. Neurocognitive and social functioning in schizophrenia: a 2.5 year follow-up study. Schizophrenia Research 44, 47-56.
2. Addington, D., Addington, J., Maticka-Tyndale, E., Joyce, J., 1992. Reliability and validity of a depression rating scale for schizophrenics. Schizophrenia Research 6, 201-208.
3. American Psychiatric Association, 1994. Diagnostic and Statistical Manual of Mental Disorders DSM-IV, 4th ed. American Psychiatric Press, Washington, DC.
4. Andreasen, N.C., 1982. Negative symptoms in schizophrenia: definition and reliability. Archives of General Psychiatry 39, 784-788.
5. Andreasen, N.C., Olsen, S., 1982. Negative vs. positive schizophrenia. Archives of General Psychiatry 39, 789-794.
6. Barch, D.M., 2005. The relationships among cognition, motivation, and emotion in schizophrenia: how much and how little we know. Schizophrenia Bulletin 31, 875-881.
7. Barkhof, E., DeHaan, L.,Meijer, C.J., Fouwels, A.J., Keet, I.P.M., Hulstijn, K.P., Schippers, G.M., Linszen, D.H., 2006. Motivational interviewing in psychotic disorders. Current Psychiatry Reviews 2, 207-213.
8. Bebbington, P., Wilkins, S., Jones, P.B., Foerster, A., Murray, R.M., Toone, B., Lewis, S., 1993. Life events and psychosis: Initial results from the premorbid functioning. British Journal of Psychiatry 162, 72-79.
9. Bellack, A.S., DiClemente, C.C., 1999. Treating substance abuse among patients with schizophrenia. Psychiatric Services 50, 75-80.
10. Bentall, R.P., Jackson, H.F., Pilgrim, D., 1988. Abandoning the concept of 'schizophrenia': some implications of validity arguments for psychological research into psychotic phenomena. British Journal of Clinical Psychology 27, 303-324.
11. Berenbaum, H., Fujita, F., 1994. Schizophrenia and personality: exploring the boundaries and connections between vulnerability and outcome. Journal of Abnormal Psychology 103, 148-158.
12. Berridge, K.C., Robinson, T.E., 1998. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Research Reviews 28, 309-369.
13. Blanchard, J.J., 1998. Hedonic capacity: implications for understanding emotional and social functioning in schizophrenia. In: Flack Jr., W.F., Laird, J.D. (Eds.), Emotions in Psychopathology: Theory and Research. Oxford University Press, New York, pp. 336-352.
14. Blanchard, J.J., Cohen, A.S., 2006. The structure of negative symptoms in schizophrenia: implications for assessment. Schizophrenia Bulletin 32, 238-245.
15. Blanchard, J.J., Mueser, K.T., Bellack, A.S., 1998. Anhedonia, positive and negative affect, and social functioning in schizophrenia. Schizophrenia Bulletin 24, 413-424.
16. Bleuler, E., 1950. Dementia Praecox or the Group of Schizophrenias. International Universities Press, New York.
17. Bryson, G., Bell, M., Kaplan, E., Greig, T., Lysaker, P., 1998. Affect recognition in deficit syndrome schizophrenia. Psychiatry Research 77, 113-120.
18. Buchanan, R.W., 2007. Persistent negative symptoms in schizophrenia: an overview. Schizophrenia Bulletin 33, 1013-1022.
19. Cacioppo, J.T., Gardner, W.L., Berntson, G.G., 1997. Beyond bipolar conceptualizations and measures: the case of attitudes and evaluative space. Personality and Social Psychology Review 1, 3-25.
20. Carter, C.S., MacDonald III, A.W., Ross, L.L., Stenger, V.A., 2001. Anterior cingulate cortex activity and impaired self-monitoring of performance in patients with schizophrenia: an event-related fMRI study. American Journal of Psychiatry 158, 1423-1428.
21. Cohen, A.S., Davis, T.E.I., 2009. Schizotypal symptoms and quality of life in a large nonclinical sample. Comprehensive Psychiatry 50 (5), 408-414.
22. Cohen, A.S., Docherty, N.M., 2004. Affective reactivity of speech and emotional experience in patients with schizophrenia. Schizophrenia Research 69, 7-14.
23. Cohen, A.S., Docherty, N.M., 2005. Symptom-oriented versus syndrome approaches to resolving heterogeneity of neuropsychological functioning in schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences 17, 384-390.
24. Cohen, A.S., Minor, K.S., 2010. Emotional experience in patients with schizophrenia revisited: meta-analysis of laboratory studies. Schizophrenia Bulletin 36, 143-150.
25. Cohen, A.S., Docherty, N.M., Nienow, T., Dinzeo, T., 2003. Self-reported stress and the deficit syndrome of schizophrenia. Psychiatry 66, 308-316.
26. Cohen, A.S., Dinzeo, T.J., Nienow, T.M., Smith, D.A., Singer, B., Docherty, N.M., 2005. Diminished emotionality and social functioning in schizophrenia. Journal of Nervous and Mental Disease 193, 796-802.
27. Cohen, A.S., Forbes, C.B., Mann, M.C., Blanchard, J.J., 2006. Specific cognitive deficits and differential domains of social functioning impairment in schizophrenia. Schizophrenia Research 81, 227-238.
28. Cohen, A.S., Saperstein, A.M., Gold, J.M., Kirkpatrick, B., Carpenter Jr.,W.T., Buchanan, R.W., 2007. Neuropsychology of the deficit syndrome: new data and meta-analysis of findings to date. Schizophrenia Bulletin 33, 1201-1212.
29. Cohen, A.S., Alpert, M., Nienow, T.M., Dinzeo, T.J., Docherty, N.M., 2008. Computerized measurement of negative symptoms in schizophrenia. Journal of Psychiatric Research 10, 827-836.
30. Cohen, A.S., St-Hilaire, A., Aakres, J.M., Docherty, N.M., 2009. The emotional underpinnings of anhedonia in schizophrenia: lexical analysis of natural speech. Cognition & Emotion 23 (3), 569-586.
31. Cools, R., Calder, A.J., Lawrence, A.D., Clark, L., Bullmore, E., Robbins, T.W., 2005. Individual differences in threat sensitivity predict serotonergic modulation of amygdala response to fearful faces. Psychopharmacology 180, 670-679.
32. Crow, T.J., 1980. Molecular pathology of schizophrenia: more than one dimension of pathology? British Medical Journal 280, 66-68.
33. Cunningham, W.A., Raye, C.L., Johnson, M.K., 2004. Implicit and explicit evaluation: fMRI correlates of valence, emotional intensity, and control in the processing of attitudes. Journal of Cognitive Neuroscience 16, 1717-1729.
34. Davidson, R.J., 2003. Affective neuroscience and psychophysiology: toward a synthesis. Psychophysiology 40, 655-665.
35. Davidson, R.J., Ekman, P., Saron, C.D., Senulis, J.A., Friesen, W.V., 1990. Approach/ withdrawal and cerebral asymmetry: emotional expression and brain physiology. Journal of Personality and Social Psychology 58, 330-341.
36. Day, R., Nielsen, J.A., Korten, A., Ernberg, G., Dube, K.C., Gebhart, J., Jablensky, A., Leon, C., Marsella, A., Olatawura, M., Sartorius, N., Stromgren, E., Takahashi, R., Wig, N., Wynne, L.C., 1987. Stressful life events preceding the acute onset of schizophrenia: a cross-national study from the World Health Organization. Culture, Medicine and Psychiatry 11, 123-205.
37. Docherty, N.M., 1996. Affective reactivity of symptoms as a process discriminator in schizophrenia. Journal of Nervous and Mental Disease 184, 535-541.
38. Earnst, K.S., Kring, A.M., 1999. Emotional responding in deficit and non-deficit schizophrenia. Psychiatry Research 88, 191-207.
39. Fox, N.A., 1991. If it's not left, it's right: electroencephalograph asymmetry and the development of emotion. American Psychologist 46, 863-872.
40. Fox, N.A., Bell, M.A., 1990. Electrophysiological indices of frontal lobe development: relations to cognitive and affective behavior in human infants over the first year of life. Annals of the New York Academy of Science 608, 677-704.
41. Gard, D.E., Kring, A.M., Gard, M.G., Horan, W.P., Green, M.F., 2007. Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophrenia Research 93, 253-260.
42. Gratz, K.L., Rosenthal, M.Z., Tull, M.T., Lejuez, C.W., Gunderson, J.G., 2006. An experimental investigation of emotion dysregulation in borderline personality disorder. Journal of Abnormal Psychology 115, 850-855.
43. Gray, J.R., 2004. Integration of emotion and cognitive control. Current Directions in Psychological Science 13, 46-48.
44. Gross, J.J., 2002. Emotion regulation: affective, cognitive, and social consequences. Psychophysiology 39, 281-291.
45. Habel, U., Klein, M., Shah, N.J., Toni, I., Zilles, K., Falkai, P., Schneider, F., 2004. Genetic load on amygdala hypofunction during sadness in nonaffected brothers of schizophrenia patients. American Journal of Psychiatry 161, 1806-1813.
46. Hariri, A.R., Mattay, V.S., Tessitore, A., Fera, F., Weinberger, D.R., 2003. Neocortical modulation of the amygdala response to fearful stimuli. Biological Psychiatry 53, 494-501.
47. Heckers, S., Goff, D., Schacter, D.L., Savage, C.R., Fischman, A.J., Alpert, N.M., Rauch, S.L., 1999. Functional imaging of memory retrieval in deficit vs nondeficit schizophrenia. Archives of General Psychiatry 56, 1117-1123.
48. Heilman, K.M., 1997. The neurobiology of emotional experience. Journal of Neuropsychiatry and Clinical Neurosciences 9, 439-448.
49. Horan, W.P., Blanchard, J.J., 2003. Neurocognitive, social, and emotional dysfunction in deficit syndrome schizophrenia. Schizophrenia Research 65, 125-137.
50. Horan, W.P., Subotnik, K.L., Reise, S.P., Ventura, J., Nuechterlein, K.H., 2005. Stability and clinical correlates of personality characteristics in recent-onset schizophrenia. Psychological Medicine 35, 995-1005.
51. Horan, W.P., Blanchard, J.J., Kring, A.M., 2006. Anhedonia in schizophrenia: a review of assessment strategies. Schizophrenia Bulletin 32, 359-373.
52. Horan, W.P., Blanchard, J.J., Clark, L.A., Green, M.F., 2008. Affective traits in schizophrenia and schizotypy. Schizophrenia Bulletin 34, 856-874.
53. Jung, Y.C., An, S.K., Seok, J.H., Kim, J.S., Oh, S.J., Moon, D.H., Kim, J.J., 2006. Neural substrates associated with evaluative processing during co-activation of positivity and negativity: a PET investigation. Biological Psychology 73, 253-261.
54. Junginger, J., 1996. Psychosis and violence: the case for a content analysis of psychotic experience. Schizophrenia Bulletin 22, 91-103.
55. Kantor, R.E., Wallner, J.M., Winder, C.L., 1953. Process and reactive schizophrenia. Journal of Consulting Psychology 17, 157-162.
56. Kay, S.R., Opler, L.A., Lindenmayer, J.P., 1988. Reliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Research 23, 99-110.
57. Kemp, R., Kirov, G., Everitt, B., Hayward, P., David, A., 1998. Randomised controlled trial of compliance therapy: 18-month follow-up. British Journal of Psychiatry 172, 413-419.
58. Kentros, M.K., Terkelsen, K., Hull, J., Smith, T.E., Goodman, M., 1997. The relationship between personality and quality of life in persons with schizoaffective disorder and schizophrenia. Quality of Life Research 6, 118-122.
59. Kerns, J.G., Cohen, J.D., MacDonald III, A.W., Cho, R.Y., Stenger, V.A., Carter, C.S., 2004. Anterior cingulate conflict monitoring and adjustments in control. Science 303, 1023-1026.
60. Kerns, J.G., Cohen, J.D., MacDonald III, A.W., Johnson, M.K., Stenger, V.A., Aizenstein, H., Carter, C.S., 2005. Decreased conflict- and error-related activity in the anterior cingulate cortex in subjects with schizophrenia. American Journal of Psychiatry 162, 1833-1839.
61. Kirkpatrick, B., Amador, X.F., 1995. The study of paranoia and suspiciousness. Biological Psychiatry 38, 496-497.
62. Kirkpatrick, B., Buchanan, R.W., 1990. Anhedonia and the deficit syndrome of schizophrenia. Psychiatry Research 31, 25-30.
63. Kirkpatrick, B., Buchanan, R.W., McKenney, P.D., Alphs, L.D., Carpenter Jr., W.T., 1989. The schedule for the deficit syndrome: an instrument for research in schizophrenia. Psychiatry Research 30, 119-123.
64. Kirkpatrick, B., Buchanan, R.W., Breier, A., Carpenter Jr., W.T., 1993. Case identification and stability of the deficit syndrome of schizophrenia. Psychiatry Research 47, 47-56.
65. Kirkpatrick, B., Buchanan, R.W., Breier, A., Carpenter Jr., W.T., 1994. Depressive symptoms and the deficit syndrome of schizophrenia. Journal of Nervous and Mental Disease 182, 452-455.
66. Kirkpatrick, B., Amador, X.F., Yale, S.A., Bustillo, J.R., Buchanan, R.W., Tohen, M., 1996. The deficit syndrome in the DSM-IV Field Trial: Part II: depressive episodes and persecutory beliefs. Schizophrenia Research 20, 79-90.
67. Kirkpatrick, B., Buchanan, R.W., Ross, D.E., Carpenter Jr., W.T., 2001. A separate disease within the syndrome of schizophrenia. Archives of Geneneral Psychiatry 58, 165-171.
68. Kirkpatrick, B., Fenton, W.S., Carpenter Jr., W.T., Marder, S.R., 2006. The NIMH-MATRICS consensus statement on negative symptoms. Schizophrenia Bulletin 32, 214-219.
69. Kraepelin, E., 1971. Dementia Praecox and Paraphrenia. Robert E. Krieger Publishing Co. Inc., New York.
70. Kwapil, T.R., 1998. Social anhedonia as a predictor of the development of schizophreniaspectrum disorders. Journal of Abnormal Psychology 107, 558-565.
71. Kwapil, T.R., Raulin, M.L., Midthun, J.C., 2000. A ten-year longitudinal study of intense ambivalence as a predictor of risk for psychopathology. Journal of Nervous and Mental Disease 188, 402-408.
72. Kwapil, T.R., Mann, M.C., Raulin, M.L., 2002. Psychometric properties and concurrent validity of the schizotypal ambivalence scale. Journal of Nervous and Mental Disease 190, 290-295.
73. Lahti, A.C., Holcomb, H.H., Medoff, D.R., Weiler, M.A., Tamminga, C.A., Carpenter Jr., W.T., 2001. Abnormal patterns of regional cerebral blood flow in schizophrenia with primary negative symptoms during an effortful auditory recognition task. American Journal of Psychiatry 158, 1797-1808.
74. Larsen, J.T., McGraw, A.P., Cacioppo, J.T., 2001. Can people feel happy and sad at the same time? Journal of Personality and Social Psychology 81, 684-696.
75. Loas, G., Noisette, C., Legrand, A., Boyer, P., 1996. Anhedonia, depression and the deficit syndrome of schizophrenia. Acta Psychiatrica Scandinavica 94, 477-479.
76. Loas, G., Boyer, P., Legrand, A., 1999. Anhedonia in the deficit syndrome of schizophrenia. Psychopathology 32, 207-219.
77. Mann, M.C., Vaughn, A.G., Barrantes-Vidal, N., Raulin, M.L., Kwapil, T.R., 2008. The schizotypal ambivalence scale as a marker of schizotypy. Journal of Nervous and Mental Disease 196, 399-404.
78. Meador-Woodruff, J.H., Haroutunian, V., Powchik, P., Davidson, M., Davis, K.L., Watson, S.J., 1997. Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex: focal abnormalities in orbitofrontal cortex in schizophrenia. Archives of General Psychiatry 54, 1089-1095.
79. Meehl, P., 1962. Schizotaxia, schizotypy, schizophrenia. American Psychology 17, 827-838.
80. Meehl, P., 1990. Toward an integrated theory of schizotaxia, schizotypy, and schizophrenia. Journal of Personality Disorders 4, 1-99.
81. Miller, N.E., 1951. Comments on theoretical models: illustrated by the development of a theory of conflict behavior. Journal of Personality 20, 82-100.
82. Mueser, K.T., Curran, P.J., McHugo, G.J., 1997. Factor structure of the Brief Psychiatric Rating Scale in schizophrenia. Psychological Assessment 9, 196-204.
83. Mueser, K.T., Salyers, M.P., Mueser, P.R., 2001. A prospective analysis of work in schizophrenia. Schizophrenia Bulletin 27, 281-296.
84. Pavlov, I.P., 1932. Experimentelle neurosen. Deutsche Zeitschrift fur Nervenheilkunde 124, 137-139.
85. Piamarta, F., Iurlaro, S., Isella, V., Atzeni, L., Grimaldi, M., Russo, A., Forapani, E., Appollonio, I., 2004. Unconventional affective symptoms and executive functions after stroke in the elderly. Archives of Gerontology and Geriatrics Supp. 9, 315-323.
86. Posner, M.I., Rothbart, M.K., 2000. Developing mechanisms of self-regulation. Development and Psychopathology 12, 427-441.
87. Rado, S., 1953. Dynamics and classification of disordered behavior. American Journal of Psychiatry 110, 406-416.
88. Rollnick, S., Miller, W.R., 1995. What is motivational interviewing? Behavioural and Cognitive Psychotherapy 23, 325-334.
89. Rottenberg, J., Kasch, K.L., Gross, J.J., Gotlib, I.H., 2002. Sadness and amusement reactivity differentially predict concurrent and prospective functioning in major depressive disorder. Emotion 2, 135-146.
90. Santangelo, G., Vitale, C., Trojano, L., Longo, K., Cozzolino, A., Grossi, D., Barone, P., 2009. Relationship between depression and cognitive dysfunctions in Parkinson's disease without dementia. Journal of Neurology 256, 632-638.
91. Sayers, S.L., Curran, P.J., Mueser, K.T., 1996. Factor structure and construct validity of the scale for the assessment of negative symptoms. Psychological Assessment 8, 269-280.
92. Tamminga, C.A., Thaker, G.K., Buchanan, R., Kirkpatrick, B., Alphs, L.D., Chase, T.N., Carpenter, W.T., 1992. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Archives of General Psychiatry 49, 522-530.
93. Taylor, S.F., Liberzon, I., Decker, L.R., Koeppe, R.A., 2002. A functional anatomic study of emotion in schizophrenia. Schizophrenia Research 58, 159-172.
94. Taylor, S.F., Phan, K.L., Britton, J.C., Liberzon, I., 2005. Neural response to emotional salience in schizophrenia. Neuropsychopharmacology 30, 984-995.
95. Waltz, J.A., Gold, J.M., 2007. Probabilistic reversal learning impairments in schizophrenia: further evidence of orbitofrontal dysfunction. Schizophrenia Research 93, 296-303.
96. Watson, C.G., Klett, W.G., Lorei, T.W., 1970. Toward an operational definition of anhedonia. Psychological Reports 26, 371-376.
97. Yon, V., Loas, G., Monestes, J.L., 2009. Relationships between schizotypy and subjective experiences in a sample of 399 university students. Comprehensive Psychiatry 50, 142-150.
98. Zvolensky, M.J., Feldner, M.T., Eifert, G.H., Brown, R.A., 2001. Affective style among smokers: Understanding anxiety sensitivity, emotional reactivity and distress tolerance using biological challenge. Addictive Behaviors 26, 901-915.