Biochemical and structural characterization of lysophosphatidic acid binding by a humanized monoclonal antibody

Journal of Molecular Biology

Volumn 408, Issue 3, 2011, Pages 462-476

  Fleming, Jonathan K ^a   Wojciak, Jonathan M ^b   Campbell, Mary Ann ^b   Huxford, Tom ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b Lpath Inc   (United States)

Author keywords

CDR; cLPA; complementarity determining region; cyclic LPA; IgG; immunoglobulin G; LPA; lysophosphatidic acid; PBS; PEG; PGE; phosphate buffered saline; polyethylene glycol; S1P; sphingosine 1 phosphate; triethylene glycol

Indexed keywords

AMINO ACID; GLYCEROPHOSPHATE; HYDROCARBON; IMMUNOGLOBULIN F(AB) FRAGMENT; LT3015; LYSOPHOSPHATIDIC ACID; MONOCLONAL ANTIBODY; PHOSPHOLIPID ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; COMPLEMENTARITY DETERMINING REGION; CRYSTAL STRUCTURE; HYDROGEN BOND; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 79953904501     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.02.061     Document Type: Article

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