Artificial compounds differentially control Dictyostelium chemotaxis and cell differentiation

Cell Structure and Function

Volumn 36, Issue 1, 2011, Pages 21-26

  Kuwayama, Hidekazu ^a   Kikuchi, Haruhisa ^b   Oshima, Yoshiteru ^b   Kubohara, Yuzuru ^c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Chemotaxis; Dictyostelium; DIF; GbpB; RegA

Indexed keywords

CYCLIC AMP; DIFFERENTIATION INDUCING FACTOR; DIFFERENTIATION INDUCING FACTOR 1; DIFFERENTIATION INDUCING FACTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CHEMOTAXIS; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

AMIDES; BIOMIMETIC MATERIALS; CELL DIFFERENTIATION; CHEMOTAXIS; DICTYOSTELIUM; MUTATION; PROTOZOAN PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

ACRASIDA; DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM;

EID: 79953886735     PISSN: 03867196     EISSN: 13473700     Source Type: Journal    
DOI: 10.1247/csf.10018     Document Type: Article

References (22)

1. Berks, M. and Kay, R.R. 1988. Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum. Dev. Biol., 126: 108-114.
2. Bosgraaf, L., Russcher, H., Smith, J.L., Wessels, D., Soll, D.R., and van Haastert, P.J.M. 2002a. A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J., 21: 4560-4570.
3. Bosgraaf, L., Russcher, H., Snippe, H., Bader, S., Wind, J., and van Haastert, P.J.M. 2002b. Identification and characterization of two unusual cGMP-stimulated phoshodiesterases in Dictyostelium. Mol. Biol. Cell, 13: 3878-3889.
4. Darmon, M., Brachet, P., and Pereira da Silva, L.H. 1975. Chemotactic signals induce cell differentiation in Dictyostelium discoideum. Proc. Natl. Acad. Sci. USA, 72: 3163-3166.
5. Gokan, N., Kikuchi, H., Nakamura, K., Oshima, Y., Hosaka, K., and Kubohara, Y. 2005. Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells. Biochem. Pharmacol., 70: 676-685.
6. Goldberg, J.M., Bosgraaf, L., van Haastert, P.J.M., and Smith, L. 2002. Identification of four candidate cGMP targets in Dictyostelium. Proc. Natl. Acad. Sci. USA, 99: 6749-6754.
7. Inouye, K. 1988. Induction by acid load of the maturation of prestalk cells in Dictyostelium discoideum. Development, 104: 669-681.
8. Kay, R.R., Berks, M., and Traynor, D. 1989. Morphogen hunting in Dictyostelium. Development, Suppl: 81-90.
9. Kay, R.R., Flatman, P., and Thompson, C.R.L. 1999. DIF signalling and cell fate. Semin. Cell Dev. Biol., 10: 577-585.
10. Kikuchi, H., Ishiko, S., Oshima, Y., Gokan, N., Hosaka, K., and Kubohara, Y. 2008. Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium. Biochem. Biophys. Res. Commun., 377: 1012-1017.
11. Konijn, T.M., van de Meene, J.G.C., Bonner, J.T., and Barkley, D.S. 1967. The acrasin activity of adenosine-3',5'-cyclic phosphate. Proc. Natl. Acad. Sci. USA, 58: 1152-1154.
12. Kopachik, W., Oohata, A., Dhokia, B., Brookman, J.J., and Kay, R.R. 1983. Dictyostelium mutants lacking DIF, a putative orphogen. Cell, 33: 397-403.
13. Kuwayama, H., Obara, S., Morio, T., Katoh, M., Urushihara, H., and Tanaka, Y. 2002. PCR-mediated generation of a gene disruption construct without the use of DNA ligase and plasmid vectors. Nucleic Acid Res., 30: E2.
14. Kuwayama, H. and Kubohara, Y. 2009. Differentiation-inducing factor-1 and -2 function also as modulators for Dictyostelium chemotaxis. PLoS ONE, 4: e6658.
15. Luciani, M.-F., Kubohara, Y., Kikuchi, H., Oshima, Y., and Golstein, P. 2009. Autophagic or necrotic cell death triggered by distinct motifs of the differentiation factor DIF-1. Cell Death Differ., 16: 564-570.
16. Masento, M.S., Morris, H.R., Taylor, G.W., Johnson, S.J., Skapski, A.C., and Kay, R.R. 1988. Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Biochem. J., 256: 23-28.
17. Morris, H.R., Taylor, G.W., Masento, M.S., Jermyn, K.A., and Kay, R.R. 1987. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. Nature, 328: 811-814.
18. Morris, H.R., Masento, M.S., Taylor, G.W., Jermyn, K.A., and Kay, R.R. 1988. Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum. Biochem. J., 249: 903-906.
19. Shaulsky, G., Escalante, R., and Loomis, W.F. 1996. Developmental signal transduction pathways uncovered by genetic suppressors. Proc. Natl. Acad. Sci. USA, 93: 15260-15265.
20. Shaulsky, G., Fuller, D., and Loomis, W.F. 1998. A cAMP-phosphodi- esterase controls PKA-dependent differentiation. Development, 125: 691-699.
21. Thompson, C.R.L. and Kay, R.R. 2000. The role of DIF-1 signaling in Dictyostelium development. Mol. Cell, 6: 1509-1514.
22. Town, D.D., Gross, J.D., and Kay, R.R. 1976. Cell differentiation without morphogenesis in Dictyostelium discoideum. Nature, 262: 717-719.