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Volumn 377, Issue 3, 2008, Pages 1012-1017

Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium

Author keywords

Dictyostelium; DIF 1; Glucose metabolism; Leukemia; Stalk cell differentiation

Indexed keywords

2,6 BIS(BENZYLOXY) 4 METHOXYBENZALDEHYDE; 2,6 BIS(BENZYLOXY) N BUTYL 4 METHOXYBENZAMIDE; 2,6 DIHYDROXY 4 METHOXYBENZALDEHYDE; 4,6 DICHLORO 2 (1 HYDROXYHEXYL) 5 METHOXYBENZENE 1,3 DIOL; DIFFERENTIATION INDUCING FACTOR; DIFFERENTIATION INDUCING FACTOR 1; N BUTYL 3,5 DICHLORO 2,6 DIHYDROXY 4 METHOXYBENZAMIDE; UNCLASSIFIED DRUG;

EID: 56049107828     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.105     Document Type: Article
Times cited : (11)

References (26)
  • 2
    • 0010467333 scopus 로고
    • Chemotactic signals induce cell differentiation in Dictyostelium discoideum
    • Darmon M., Brachet P., and Pereira da Silva L.H. Chemotactic signals induce cell differentiation in Dictyostelium discoideum. Proc. Natl. Acad. Sci. USA 72 (1975) 3163-3166
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 3163-3166
    • Darmon, M.1    Brachet, P.2    Pereira da Silva, L.H.3
  • 3
    • 0016751044 scopus 로고
    • Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells
    • Gerisch G., Fromm H., Husesgen A., and Wick U. Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells. Nature 255 (1975) 547-549
    • (1975) Nature , vol.255 , pp. 547-549
    • Gerisch, G.1    Fromm, H.2    Husesgen, A.3    Wick, U.4
  • 4
    • 0017160099 scopus 로고
    • Cell differentiation without morphogenesis in Dictyostelium discoideum
    • Town C.D., Gross J.D., and Kay R.R. Cell differentiation without morphogenesis in Dictyostelium discoideum. Nature 262 (1976) 717-719
    • (1976) Nature , vol.262 , pp. 717-719
    • Town, C.D.1    Gross, J.D.2    Kay, R.R.3
  • 5
    • 0023240287 scopus 로고
    • Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum
    • Morris H.R., Taylor G.W., Masento M.S., Jermyn K.A., and Kay R.R. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. Nature 328 (1987) 811-814
    • (1987) Nature , vol.328 , pp. 811-814
    • Morris, H.R.1    Taylor, G.W.2    Masento, M.S.3    Jermyn, K.A.4    Kay, R.R.5
  • 6
    • 0024851990 scopus 로고
    • Morphogen hunting in Dictyostelium discoideum
    • Kay R.R., Berks M., and Traynor D. Morphogen hunting in Dictyostelium discoideum. Dev. Suppl. (1989) 81-90
    • (1989) Dev. Suppl. , pp. 81-90
    • Kay, R.R.1    Berks, M.2    Traynor, D.3
  • 7
    • 0023791673 scopus 로고
    • Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues
    • Masento M.S., Morris H.R., Taylor G.W., Johnson S.J., Skapski A.C., and Kay R.R. Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Biochem. J. 256 (1988) 23-28
    • (1988) Biochem. J. , vol.256 , pp. 23-28
    • Masento, M.S.1    Morris, H.R.2    Taylor, G.W.3    Johnson, S.J.4    Skapski, A.C.5    Kay, R.R.6
  • 8
    • 0023955045 scopus 로고
    • Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum
    • Morris H.R., Masento M.S., Taylor G.W., Jermyn K.A., and Kay R.R. Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum. Biochem. J. 249 (1988) 903-906
    • (1988) Biochem. J. , vol.249 , pp. 903-906
    • Morris, H.R.1    Masento, M.S.2    Taylor, G.W.3    Jermyn, K.A.4    Kay, R.R.5
  • 10
    • 0028170061 scopus 로고
    • + concentrations determine cell fate in Dictyostelium discoideum
    • + concentrations determine cell fate in Dictyostelium discoideum. FASEB J. 8 (1994) 869-874
    • (1994) FASEB J. , vol.8 , pp. 869-874
    • Kubohara, Y.1    Okamoto, K.2
  • 11
    • 0029791315 scopus 로고    scopus 로고
    • 2+ levels mediates stalk gene induction by differentiation inducing factor in Dictyostelium
    • 2+ levels mediates stalk gene induction by differentiation inducing factor in Dictyostelium. EMBO J. 15 (1996) 5177-5183
    • (1996) EMBO J. , vol.15 , pp. 5177-5183
    • Schaap, P.1    Nebl, T.2    Fisher, P.R.3
  • 14
    • 0028904694 scopus 로고
    • DIF-1, morphogen of Dictyostelium discoideum, induces the erythroid differentiation in murine and human leukemia cells
    • Asahi K., Sakurai A., Takahashi N., Kubohara Y., Okamoto K., and Tanaka Y. DIF-1, morphogen of Dictyostelium discoideum, induces the erythroid differentiation in murine and human leukemia cells. Biochem. Biophys. Res. Commun. 208 (1995) 1036-1039
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 1036-1039
    • Asahi, K.1    Sakurai, A.2    Takahashi, N.3    Kubohara, Y.4    Okamoto, K.5    Tanaka, Y.6
  • 15
    • 0028895686 scopus 로고
    • Differentiation-inducing factor of D. discoideum raises intracellular calcium concentration and suppresses cell growth in rat pancreatic AR42J cells
    • Kubohara Y., Saito Y., and Tatemoto K. Differentiation-inducing factor of D. discoideum raises intracellular calcium concentration and suppresses cell growth in rat pancreatic AR42J cells. FEBS Lett. 359 (1995) 119-122
    • (1995) FEBS Lett. , vol.359 , pp. 119-122
    • Kubohara, Y.1    Saito, Y.2    Tatemoto, K.3
  • 16
    • 0028792250 scopus 로고
    • Putative morphogen, DIF, of Dictyostelium discoideum induces apoptosis in rat pancreatic AR42J cells
    • Kubohara Y., Kimura C., and Tatemoto K. Putative morphogen, DIF, of Dictyostelium discoideum induces apoptosis in rat pancreatic AR42J cells. Dev. Growth Differ. 37 (1995) 711-716
    • (1995) Dev. Growth Differ. , vol.37 , pp. 711-716
    • Kubohara, Y.1    Kimura, C.2    Tatemoto, K.3
  • 17
    • 0031577299 scopus 로고    scopus 로고
    • DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60
    • Kubohara Y. DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60. Biochem. Biophys. Res. Commun. 236 (1997) 418-422
    • (1997) Biochem. Biophys. Res. Commun. , vol.236 , pp. 418-422
    • Kubohara, Y.1
  • 18
    • 0032829310 scopus 로고    scopus 로고
    • Effects of differentiation-inducing factors (DIFs) of Dictyostelium discoideum on the human leukemia K562 cells: DIF-3 is the most potent anti-leukemic agent
    • Kubohara Y. Effects of differentiation-inducing factors (DIFs) of Dictyostelium discoideum on the human leukemia K562 cells: DIF-3 is the most potent anti-leukemic agent. Eur. J. Pharmacol. 381 (1999) 57-62
    • (1999) Eur. J. Pharmacol. , vol.381 , pp. 57-62
    • Kubohara, Y.1
  • 19
    • 0033527433 scopus 로고    scopus 로고
    • The putative morphogen, DIF-1, of Dictyostelium discoideum activates Akt/PKB in human leukemia K562 cells
    • Kubohara Y., and Hosaka K. The putative morphogen, DIF-1, of Dictyostelium discoideum activates Akt/PKB in human leukemia K562 cells. Biochem. Biophys. Res. Commun. 263 (1999) 790-796
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 790-796
    • Kubohara, Y.1    Hosaka, K.2
  • 20
    • 0037473051 scopus 로고    scopus 로고
    • Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK dependent pathway
    • Kanai M., Konda Y., Nakajima T., Izumi Y., Nanakin A., Kanda N., Kubohara Y., and Chiba T. Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK dependent pathway. Oncogene 22 (2003) 548-554
    • (2003) Oncogene , vol.22 , pp. 548-554
    • Kanai, M.1    Konda, Y.2    Nakajima, T.3    Izumi, Y.4    Nanakin, A.5    Kanda, N.6    Kubohara, Y.7    Chiba, T.8
  • 21
    • 0037646484 scopus 로고    scopus 로고
    • Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3β and degrades cyclin D1 in mammalian cells
    • Takahashi-Yanaga F., Taba Y., Miwa Y., Kubohara Y., Watanabe Y., Hirata M., Morimoto S., and Sasaguri T. Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3β and degrades cyclin D1 in mammalian cells. J. Biol. Chem. 278 (2003) 9663-9670
    • (2003) J. Biol. Chem. , vol.278 , pp. 9663-9670
    • Takahashi-Yanaga, F.1    Taba, Y.2    Miwa, Y.3    Kubohara, Y.4    Watanabe, Y.5    Hirata, M.6    Morimoto, S.7    Sasaguri, T.8
  • 22
    • 23044435107 scopus 로고    scopus 로고
    • Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells
    • Gokan N., Kikuchi H., Nakamura K., Oshima Y., Hosaka K., and Kubohara Y. Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells. Biochem. Pharmacol. 70 (2005) 676-685
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 676-685
    • Gokan, N.1    Kikuchi, H.2    Nakamura, K.3    Oshima, Y.4    Hosaka, K.5    Kubohara, Y.6
  • 23
    • 1642497589 scopus 로고    scopus 로고
    • Differentiation-inducing factor-1-induced growth arrest of K562 leukemia cells involves the reduction of ERK1/2 activity
    • Akaishi E., Narita T., Kawai S., Miwa Y., Sasaguri T., Hosaka K., and Kubohara Y. Differentiation-inducing factor-1-induced growth arrest of K562 leukemia cells involves the reduction of ERK1/2 activity. Eur. J. Pharmacol. 485 (2004) 21-29
    • (2004) Eur. J. Pharmacol. , vol.485 , pp. 21-29
    • Akaishi, E.1    Narita, T.2    Kawai, S.3    Miwa, Y.4    Sasaguri, T.5    Hosaka, K.6    Kubohara, Y.7
  • 24
    • 1942538254 scopus 로고    scopus 로고
    • Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) is a pharmacological target of differentiation-inducing factor-1, an anti-tumor agent isolated from Dictyostelium
    • Shimizu K., Murata T., Tagawa T., Takahashi K., Ishikawa R., Abe Y., Hosaka K., and Kubohara Y. Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) is a pharmacological target of differentiation-inducing factor-1, an anti-tumor agent isolated from Dictyostelium. Cancer Res. 64 (2004) 2568-2571
    • (2004) Cancer Res. , vol.64 , pp. 2568-2571
    • Shimizu, K.1    Murata, T.2    Tagawa, T.3    Takahashi, K.4    Ishikawa, R.5    Abe, Y.6    Hosaka, K.7    Kubohara, Y.8
  • 25
    • 34347401616 scopus 로고    scopus 로고
    • Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells
    • Omata W., Shibata H., Nagasawa M., Kojima I., Kikuchi H., Oshima Y., Hosaka K., and Kubohara Y. Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells. FEBS J. 274 (2007) 3392-3404
    • (2007) FEBS J. , vol.274 , pp. 3392-3404
    • Omata, W.1    Shibata, H.2    Nagasawa, M.3    Kojima, I.4    Kikuchi, H.5    Oshima, Y.6    Hosaka, K.7    Kubohara, Y.8
  • 26
    • 0020531928 scopus 로고
    • Dictyostelium mutants lacking DIF, a putative morphogen
    • Kopachik W., Oohata A., Dhokia B., Brookman J.J., and Kay R.R. Dictyostelium mutants lacking DIF, a putative morphogen. Cell 33 (1983) 397-403
    • (1983) Cell , vol.33 , pp. 397-403
    • Kopachik, W.1    Oohata, A.2    Dhokia, B.3    Brookman, J.J.4    Kay, R.R.5


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