Expression and clinical significance of ZO-1 in patients with non-small cell lung cancer

Chinese Journal of Lung Cancer

Volumn 14, Issue 2, 2011, Pages 146-150

  Wang, Yekai ^a   Zhou, Jihang ^a   Zeng, Fang ^a   Huang, Yanyan ^a   Zhou, Shiquan ^a   Liu, Xiaoguang ^a  

^a Zhoushan Hospital   (China)

Author keywords

Immunohistochemistry; Lung neoplasms; ZO 1 protein

Indexed keywords

MESSENGER RNA; PROTEIN ZO1;

ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; METASTASIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 79953886335     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: 10.3779/j.issn.1009-3419.2011.02.08     Document Type: Article

References (17)

1. Ding GR, Qiu LB, Wang XW, et al. EMP-induced alterations of tight junction protein expression and disruption of the blood-brain barrier. Toxicol Lett, 2010, 196(3): 154-160.
2. Zhang JB, Du XG, Zhang H, et al. Breakdown of the gut barrier in patients with multiple organ dysfunction syndrome is attenuated by continuous blood purification: effects on tight junction structural proteins. Int J Artif Organs, 2010, 33(1): 5-14.
3. Fanning AS, Ma TY, Anderson JM. Isolation and functional characterization of the actin binding region in the tight junction protein ZO-1. FASEB J, 2002, 16(13): 1835-1837.
4. Yu D, Marchiando AM, Weber CR, et al. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci USA, 2010, 107(18): 8237-8241.
5. Jinn Y, Inase N. Connexin 43, E-cadherin, beta-catenin and ZO-1 expression, and aberrant methylation of the connexin 43 gene in NSCLC. Anticancer Res, 2010, 30(6): 2271-2278.
6. Fiorini C, Gilleron J, Carette D, et al. Accelerated internalization of junctional membrane proteins (connexin 43, N-cadherin and ZO-1) within endocytic vacuoles: an early event of DDT carcinogenicity. Biochim Biophys Acta, 2008, 1778(1): 56-67.
7. Orban E, Szabo E, Lotz G, et al. Different expression of occludin and ZO-1 in primary and metastatic liver tumors. Pathol Oncol Res, 2008, 14(3): 299-306.
8. Tsukita S, Yamazaki Y, Katsuno T, et al. Tight junction-based epithelial microenvironment and cell proliferation. Oncogene, 2008, 27(55): 6930-6938.
9. Severson EA, Kwon M, Hilgarth RS, et al. Glycogen synthase kinase 3 (GSK-3) influences epithelial barrier function by regulating Occludin, Claudin- 1 and E-cadherin expression. Biochem Biophys Res Commun, 2010, 397(3): 592-597.
10. Ko JA, Murata S, Nishida TS. Up-regulation of the tight-junction protein ZO-1 by substance P and IGF-1 in A431 cells. Cell Biochem Funct, 2009, 27(6): 388-394.
11. Marzioni D, Banita M, Felici A, et al. Expression of ZO-1 and occludin in normal human placenta and in hydatidiform moles. Mol Hum Reprod, 2001, 7(3): 279-285.
12. Pfeiffer F, Kumar V, Butz S, et al. Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. Eur J Immunol, 2008, 38(8): 2142-2155.
13. Polette M, Mestdagt M, Bindels S, et al. Beta-catenin and ZO-1: shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes. Cells Tissues Organs, 2007, 185(1-3): 61-65.
14. Tuomi S, Mai A, Nevo J, et al. PKCepsilon regulation of an alpha5 integrin- ZO-1 complex controls lamellae formation in migrating cancer cells. Sci Signal, 2009, 2(77): ra32.
15. Zen K, Yasui K, Gen Y, et al. Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma. Oncogene, 2009, 28(32): 2910-2918.
16. Ohtani S, Terashima M, Satoh J, et al. Expression of tight-junction-associated proteins in human gastric cancer: downregulation of claudin-4 correlates with tumor aggressiveness and survival. Gastric Cancer, 2009, 12(1): 43-51.
17. Greatens TM, Niehans GA, Rubins JB, et al. Do molecular markers predict survival in non-small-cell lung cancer? Am J Respir Crit Care Med, 1998, 157(4Pt1): 1093-1097.