High-resolution esophageal pressure topography is superior to conventional sleeve manometry for the detection of transient lower esophageal sphincter relaxations associated with a reflux event

Neurogastroenterology and Motility

Volumn 23, Issue 5, 2011, Pages

  Rohof, W O A ^a   Boeckxstaens, G E E ^a,b   Hirsch, D P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Gastro esophageal reflux disease; High resolution esophageal pressure topography; Transient lower esophageal sphincter relaxation

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; ESOPHAGUS MANOMETRY; ESOPHAGUS MOTILITY; ESOPHAGUS PRESSURE; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; LOWER ESOPHAGUS SPHINCTER; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; CATHETERS; ESOPHAGEAL SPHINCTER, LOWER; GASTROESOPHAGEAL REFLUX; HUMANS; MALE; MANOMETRY; MIDDLE AGED; MUSCLE RELAXATION;

EID: 79953858074     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2010.01654.x     Document Type: Article

References (26)

1. Kahrilas PJ, Shaheen NJ, Vaezi MF et al. American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease. Gastroenterology 2008; 135: 1383-91.
2. Dent J, Dodds WJ, Friedman RH et al. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest 1980; 65: 256-67.
3. Dodds WJ, Dent J, Hogan WJ et al. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med 1982; 307: 1547-52.
4. Sifrim D, Holloway R. Transient lower esophageal sphincter relaxations: how many or how harmful? Am J Gastroenterol 2001; 96: 2529-32.
5. Beaumont H, Bennink R, de JJ, Boeckxstaens G. The position of the acid pocket as a major risk factor for acidic reflux in healthy subjects and GERD patients. Gut 2010; 59: 441-51.
6. Page AJ, Blackshaw LA. An in vitro study of the properties of vagal afferent fibres innervating the ferret oesophagus and stomach. J Physiol 1998; 512: 907-16.
7. Babaei A, Bhargava V, Korsapati H, Zheng WH, Mittal RK. A unique longitudinal muscle contraction pattern associated with transient lower esophageal sphincter relaxation. Gastroenterology 2008; 134: 1322-31.
8. Boeckxstaens GE, Tytgat GN. More pathophysiologically oriented treatment of GORD? Lancet 2002; 359: 1267-8.
9. Boeckxstaens GE. Reflux inhibitors: a new approach for GERD? Curr Opin Pharmacol 2008; 8: 685-9.
10. Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995; 268: G128-33.
11. Dent J. Pathogenesis of gastro-oesophageal reflux disease and novel options for its therapy. Neurogastroenterol Motil 2008; 20(Suppl 1): 91-102.
12. Holloway RH, Boeckxstaens G, Penagini R et al. Objective definition and detection of transient lower esophageal relaxation revisited: is there room for improvement? Gastroenterology 2009; 136: A527.
13. Fox MR, Bredenoord AJ. Oesophageal high-resolution manometry: moving from research into clinical practice. Gut 2008; 57: 405-23.
14. Grubel C, Hiscock R, Hebbard G. Value of spatiotemporal representation of manometric data. Clin Gastroenterol Hepatol 2008; 6: 525-30.
15. Pandolfino JE, Ghosh SK, Rice J, Clarke JO, Kwiatek MA, Kahrilas PJ. Classifying esophageal motility by pressure topography characteristics: a study of 400 patients and 75 controls. Am J Gastroenterol 2008; 103: 27-37.
16. Ghosh SK, Pandolfino JE, Rice J, Clarke JO, Kwiatek M, Kahrilas PJ. Impaired deglutitive EGJ relaxation in clinical esophageal manometry: a quantitative analysis of 400 patients and 75 controls. Am J Physiol Gastrointest Liver Physiol 2007; 293: G878-85.
17. Pandolfino JE, Zhang QG, Ghosh SK, Han A, Boniquit C, Kahrilas PJ. Transient lower esophageal sphincter relaxations and reflux: mechanistic analysis using concurrent fluoroscopy and high-resolution manometry. Gastroenterology 2006; 131: 1725-33.
18. Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Sleeve sensor versus high-resolution manometry for the detection of transient lower esophageal sphincter relaxations. Am J Physiol Gastrointest Liver Physiol 2005; 288: G1190-4.
19. Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Intermittent spatial separation of diaphragm and lower esophageal sphincter favors acidic and weakly acidic reflux. Gastroenterology 2006; 130: 334-40.
20. Sifrim D, Holloway R, Silny J et al. Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001; 120: 1588-98.
21. Sifrim D, Castell D, Dent J, Kahrilas PJ. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut 2004; 53: 1024-31.
22. Kahrilas PJ, Sifrim D. High-resolution manometry and impedance-pH/manometry: valuable tools in clinical and investigational esophagology. Gastroenterology 2008; 135: 756-69.
23. Pandolfino JE, Ghosh SK, Zhang Q, Han A, Kahrilas PJ. Upper sphincter function during transient lower oesophageal sphincter relaxation (tLOSR); it is mainly about microburps. Neurogastroenterol Motil 2007; 19: 203-10.
24. Kuribayashi S, Massey BT, Hafeezullah M et al. Terminating motor events for TLESR are influenced by the presence and distribution of refluxate. Am J Physiol Gastrointest Liver Physiol 2009; 297: G71-5.
25. Babaei A, Bhargava V, Mittal RK. Upper esophageal sphincter during transient lower esophageal sphincter relaxation: effects of reflux content & posture. Am J Physiol Gastrointest Liver Physiol 2010; 298: G601-7.
26. Kwiatek MA, Post J, Pandolfino JE, Kahrilas PJ. Transient lower oesophageal sphincter relaxation in achalasia: everything but LOS relaxation. Neurogastroenterol Motil 2009; 21: 1294-e123.