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Volumn 2, Issue 4, 2011, Pages 274-277

Platinum-oxazoline complexes as anti-cancer agents: Syntheses, characterisation and initial biological studies

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYL 2 OXAZOLINE; 4,4 DIMETHYL 2 [O ANILINYL] 2 OXAZOLINE; ANTINEOPLASTIC METAL COMPLEX; CISPLATIN; OXAZOLINE DERIVATIVE; PLATINUM OXAZOLINE COMPLEX; PYRIDINE 2 CARBOXYANIL[O (4,4 DIMETHYL 2 OXAZOLINYL) IDE]; UNCLASSIFIED DRUG;

EID: 79953840928     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c0md00211a     Document Type: Article
Times cited : (29)

References (31)
  • 15
    • 79953847080 scopus 로고    scopus 로고
    • note
    • +).
  • 16
    • 79953892186 scopus 로고    scopus 로고
    • note
    • -3. Selected bond lengths (Å) and angles (°): Pt-Cl1 2.305(1), Pt-Cl2 2.299(2), Pt-N1 1.995(4), Pt-N2 2.042(7), N1-C2 1.282(9); Cl1-Pt-Cl2 91.79(6), Cl1-Pt-N1 179.0(2), Cl1-Pt-N2 90.3(2), N1-Pt-N2 88.9(2) Cl1-N2-C7 121.1(6).
  • 17
    • 79953859046 scopus 로고    scopus 로고
    • note
    • 2), 6.65 (m, 1H, Ar H), 6.82 (m, 1H, Ar H), 7.28 (m, 1H, Ar H), 7.63 (m, 1H, Ar H). Anal. Calc. (Found): C 28.96 (28.44); H 3.09 (2.97); N 6.14 (6.13)%. Crystals suitable for X-ray diffraction work were obtained by recrystallisation of 2 from aq. 95% EtOH at RT.
  • 18
    • 79953896503 scopus 로고    scopus 로고
    • note
    • -3. Selected bond lengths (Å) and angles (°): Pt-Cl1 2.294(3), Pt-Cl2 2.324(3), Pt-N1 2.043(7), Pt-N2 2.06(1), N1-C5 1.28(1); Cl1-Pt- Cl2 88.3(1), Cl1-Pt-N1 174.1(2), Cl1-Pt-N2 90.6(3), N1-Pt-N2 84.3(3) Pt1-N2-C7 110.0(7).
  • 19
    • 79953881232 scopus 로고    scopus 로고
    • note
    • 2). Anal. Calc. (Found): C 25.87 (25.65); H 3.91 (3.51); N 6.03 (6.01)%.
  • 20
    • 79953867176 scopus 로고    scopus 로고
    • Full details on the X-ray structural characterisation of complex 3 will be published separately: unpublished results
    • Full details on the X-ray structural characterisation of complex 3 will be published separately: Gossage, R. A.; Jenkins, H. A. unpublished results.
    • Gossage, R.A.1    Jenkins, H.A.2
  • 27
    • 79953851701 scopus 로고    scopus 로고
    • note
    • 50 values were determined as the drug concentration that reduced the absorbance to 50% of that in untreated control wells.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.