Development and validation of a cell-based assay for the nuclear receptor retinoid-related orphan receptor gamma

Assay and Drug Development Technologies

Volumn 9, Issue 2, 2011, Pages 125-135

  Wilkinson, Jennifer ^a   Hallis, Tina ^a   Hermanson, Spencer ^a   Bi, Kun ^a  

^a Life Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

24 HYDROXYCHOLESTEROL; 3,5 DI TERT BUTYL 4' CHALCONECARBOXYLIC ACID; 4 (2,6 DICHLORO 4 PYRIDINYL) 1 (1,3 DIMETHYL 4 ISOPROPYL 1H PYRAZOLO[3,4 B]PYRIDIN 6 YL)SEMICARBAZIDE; 6 (1,3 DIOXO 1H,3H BENZO[DE]ISOQUINOLIN 2 YL) N HYDROXYHEXANAMIDE; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; BETA LACTAMASE; CHOLESTEROL DERIVATIVE; CP 33918; DOXYCYCLINE; GBR 13609; HYBRID PROTEIN; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; NEFAZODONE; RECEPTOR BLOCKING AGENT; RETINOIC ACID; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STEROL DERIVATIVE; TETRACYCLINE; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; VANOXERINE; ZM 306416;

ARTICLE; CELL ASSAY; DNA BINDING; DRUG ACTIVITY; DRUG SCREENING; DRUG TARGETING; FOLLOW UP; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIGAND BINDING; PROTEIN DOMAIN; REPORTER GENE; RNA INTERFERENCE;

BIOLOGICAL ASSAY; GENE KNOCKDOWN TECHNIQUES; GENE LIBRARY; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; ORPHAN NUCLEAR RECEPTORS; PROTEIN BINDING;

EID: 79953805665     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2010.0290     Document Type: Article

References (14)

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