DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma

Cancer

Volumn 117, Issue 8, 2011, Pages 1649-1660

  Hirata, Hiroshi ^a   Hinoda, Yuji ^b   Majid, Shahana ^a   Chen, Yi ^a   Zaman, Mohd S ^a   Ueno, Koji ^a   Nakajima, Koichi ^c   Tabatabai, Z Laura ^a   Ishii, Nobuhisa ^c   Dahiya, Rajvir ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

3 (4; 5 dimethylthiazol 2 yl) 5 (3 carboxymethoxyphenyl) 2 (4 sulfophenyl) 2H tetrazolium assay; canonical pathway; colony formation assay; fluorescence activated cell sorting; in vivo study; invasion assay; noncanonical pathway; real time reverse transcriptase polymerase chain reaction; T cell factor lymphoid enhancer factor reporter assay; wound healing assay

Indexed keywords

BETA CATENIN; CASPASE 3; CYCLIN D1; DICKKOPF 4 PROTEIN; GELATINASE A; GLYCOPROTEIN; LYMPHOID ENHANCER FACTOR 1; MYC PROTEIN; STRESS ACTIVATED PROTEIN KINASE; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CELL CYCLE; CELL INVASION; CELL MIGRATION; CELL NUCLEUS; CELL VIABILITY; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; DISTANT METASTASIS; ENZYME ACTIVATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INHIBITION KINETICS; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; LYMPH NODE METASTASIS; MALE; MOUSE; NONHUMAN; NUDE MOUSE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR GROWTH; WOUND HEALING;

ADULT; AGED; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CLONE CELLS; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 79953798397     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25666     Document Type: Article

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