Intrathecal herpes simplex virus type 1 amplicon vector-mediated human proenkephalin reduces chronic constriction injury-induced neuropathic pain in rats

Molecular Medicine Reports

Volumn 4, Issue 3, 2011, Pages 529-533

  Zou, Wangyuan ^a   Guo, Qulian ^a   Chen, Chan ^a   Yang, Yong ^a   Wang, E ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Herpes simplex virus type 1; Human enkephalins; Intrathecal; Neuropathic pain

Indexed keywords

BETA GALACTOSIDASE; HERPESVIRUS VECTOR; LEUCINE ENKEPHALIN; MESSENGER RNA; PROENKEPHALIN;

ALLODYNIA; AMPLICON; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; HYPERALGESIA; LOW DRUG DOSE; MALE; NERVE COMPRESSION; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; PAW WITHDRAWAL MECHANICAL THRESHOLD; PAW WITHDRAWAL THERMAL LATENCY; RAT; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINATION;

ANIMALS; CHRONIC DISEASE; CONSTRICTION; ENKEPHALIN, LEUCINE; ENKEPHALINS; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; HYPERALGESIA; INJECTIONS, SPINAL; MALE; NALOXONE; NEURALGIA; PLASMIDS; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD; TIME FACTORS;

HUMAN HERPESVIRUS 1; RATTUS;

EID: 79953767560     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.445     Document Type: Article

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