Primary structure of guinea pig preprodynorphin and preproenkephalin mRNAs: Multiple transcription initiation sites for preprodynorphin

Brain Research Bulletin

Volumn 63, Issue 2, 2004, Pages 119-126

  LaForge, K Steven ^a,b   Nyberg, Fred ^b   Kreek, Mary Jeanne ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Endogenous opioid system; mRNA structure; Neuropeptide

Indexed keywords

MESSENGER RNA; PREPRODYNORPHIN; PREPROENKEPHALIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DNA LIBRARY; DNA SEQUENCE; DNA STRUCTURE; ENZYME ASSAY; EXON; GENE MAPPING; GENE SEQUENCE; GUINEA PIG; INTRON; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA ANALYSIS; RNA SEQUENCE; RNA STABILITY; RNA STRUCTURE; RNA TRANSCRIPTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION SITE;

ANIMALS; BASE SEQUENCE; BRAIN; DYNORPHINS; ENKEPHALINS; GUINEA PIGS; MALE; MOLECULAR SEQUENCE DATA; PITUITARY GLAND; PROTEIN PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION INITIATION SITE;

EID: 2342559921     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2004.01.008     Document Type: Article

References (41)

1. Beaulier M., Ouellette M., Desgroseillers L., Brakier-Gringras L. Molecular cloning and characterization of the hamster preproenkephalin A cDNA. DNA Cell Biol. 13:1994;933-940
2. Brooks P.J., Funabashi T., Kleopoulos S.P., Mobbs C.V., Pfaff D.W. Cell-specific expression of preproenkephalin intronic heteronuclear RNA in the rat forebrain. Mol. Brain Res. 19:1993;22-30
3. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159
4. Civelli O., Douglass J., Goldstein A., Herbert E. Sequence and expression of the rat prodynorphin gene. Proc. Natl. Acad. Sci. U.S.A. 82:1985;4291-4295
5. Comb M.P., Seeburg H., Adelman J., Eiden L., Herbert E. Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (London). 295:1982;663-666
6. Culpepper-Morgan J., Kreek M.J., Holt P.R., LaRoche D., Zhang J., O'Bryan L. Orally administered kappa as well as mu opiate antagonists delay gastrointestinal transit time in the guinea pig. Life Sci. 42:1988;2073-2077
7. Day R., Schaefer M.K.-H., Collard M.W., Watson S.J., Akil H. Atypical prodynorphin gene expression in corticosteroid-producing cells of the rat adrenal gland. Proc. Natl. Acad. Sci. U.S.A. 88:1991;1320-1324
8. Douglass J., McMurray C.T., Garrett J.E., Adelman J.P., Calavetta L. Characterization of the rat prodynorphin gene. Mol. Endocrinol. 3:1989;2070-2078
9. Feinberg A.P., Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13
10. Garrett J., Collard M.V., Douglass J. Translational control of germ cell-expressed mRNA imposed by alternative splicing: opioid gene expression in rat testis. Mol. Cell. Biol. 9:1989;4381-4389
11. Geijer T., Telkov M., Terenius L. Characterization of human prodynorphin gene transcripts. Biochem. Biophys. Res. Commun. 215:1995;881-888
12. Gubler U., Seeburg P., Hoffman B.J., Gage L.P., Udenfriend S. Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides. Nature (London). 295:1982;206-208
13. Horikawa S., Takai T., Toyosato M., Takahashi H., Noda M., Kakidani H., Kubo T., Hirose T., Inayama S., Hayashida H., Miyata T., Numa S. Isolation and structural organization of the human preproenkephalin B gene. Nature (London). 306:1983;611-614
14. Howells R.D., Kilpatrick D.L., Bhatt R., Monahan J.J., Poonian M., Udenfriend S. Molecular cloning and sequence determination of rat preproenkephalin cDNA: sensitive probe for studying transcriptional changes in rat tissues. Proc. Natl. Acad. Sci. U.S.A. 81:1984;7651-7655
15. Jiang H., Weesner G.D., Malven P.V. cDNA sequence and expression of bovine prodynorphin. Gene. 186:1997;279-283
16. Josefsen K., Buschard K., Sorensen L.R., Wollike M., Ekman M., Birkenbach M. Glucose stimulation of pancreatic beta-cell lines induces expression and secretion of dynorphin. Endocrinology. 139:1998;4329-4336
17. Kakidani H., Furutani Y., Takahashi H., Noda M., Morimoto Y., Hirose T., Asai M., Inayama S., Nakanishi S., Numa S. Cloning and sequence analysis of cDNA for porcine b-neo-endorphin/dynorphin precursor. Nature (London). 298:1982;245-249
18. Kilpatrick D.L., Borland K., Jin D.F. Differential expression of opioid peptide genes by testicular germ cells and somatic cells. Proc. Natl. Acad. Sci. U.S.A. 84:1987;5695-5699
19. Kilpatrick D.L., Howells R.D., Noe M., Bailey L.C., Udenfriend S. Expression of preproenkephalin-like mRNA and its peptide products in mammalian testis and ovary. Proc. Natl. Acad. Sci. U.S.A. 82:1985;7467-7469
20. Kilpatrick D.L., Zinn S.A., Fitzgerald M., Higuchi H., Sabol S.L., Meyerhardt J. Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells. Mol. Cell. Biol. 10:1990;3717-3726
21. LaForge K.S., Unterwald E.M., Kreek M.J. Structure and expression of the guinea pig preproenkephalin gene: site-specific cleavage in the 3′ untranslated region yields truncated mRNA transcripts in specific brain regions. Mol. Cell. Biol. 15:1995;2080-2089
22. Legon S., Glover D.M., Hughes J., Lowry P.J., Rigby P.W.J., Watson C.J. The structure and expression of the preproenkephalin gene. Nucleic Acids Res. 10:1982;7905-7918
23. T. Maniatis, E.F. Fritsch, J. Sambrook, Molecular Cloning, a Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1982.
24. Martens G.J.M., Herbert E. Polymorphism and absence of Leu-enkephalin sequences in proenkephalin genes in Xenopus laevis. Nature (London). 310:1984;251-254
25. Melton D.A., Kneg P.A., Rebagliati M.R., Maniatis T., Zinn K., Green M.R. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:1984;7035-7056
26. Noda M., Furutani Y., Takahashi H., Toyosato M., Hirose T., Inayama S., Nakanishi S., Numa S. Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin. Nature (London). 295:1982;202-206
27. Pham K., LaForge K.S., Kreek M.J. Comparison of methods for quantitation of radioactivity in protected hybrids in RNase protection assays. BioTechniques. 25:1998;198-200
28. Rao S.M., Howells R.D. cis-Acting elements in the 5′-untranslated region of rat testis proenkephalin mRNA regulate translation of the precursor. J. Biol. Chem. 268:1993;22164-22169
29. Rosen H., Douglass J., Herbert E. Isolation and characterization of the rat proenkephalin gene. J. Biol. Chem. 259:1984;14309-14313
30. Sharif N.A., Hughes J. Discrete mapping of brain mu and delta opioid receptors using selective peptides: quantitative autoradiography, species differences and comparison with kappa receptors. Peptides. 10:1989;499-522
31. Sharifi N., Ament M., Brennan M.B., Hochschwender U. Isolation and characterization of the mouse homolog of the preprodynorphin (Pdyn) gene. Neuropeptides. 33:1999;236-238
32. Tavani A., Gambino M.C., Petrillo P. The opioid kappa-selective compound U-50, 488H does not inhibit intestinal propulsion in rats. J. Pharm. Pharmacol. 36:1984;343-344
33. 2 opioid receptors in rat and guinea pig brain. Brain Res. 562:1991;57-65
34. Yoshikawa K., Maruyama K., Aizawa T., Yamamoto A. A new species of enkephalin precursor mRNA with a distinct 5′-untranslated region in haploid germ cells. FEBS Lett. 246:1989;193-196
35. Yoshikawa K., Williams C., Sabol S.L. Rat brain preproenkephalin mRNA: cDNA cloning, primary structure, and distribution in the central nervous system. J. Biol. Chem. 259:1984;14301-14308
36. 3H ]Dynorphin A binding and k selectivity of prodynorphin peptides in rat, guinea pig and monkey brain Eur. J. Pharmacol. 121:1986;355-365
37. Yuferov V.P., LaForge K.S., Spangler R., Maggos C.E., Kreek M.J. Guinea pig preprodynorphin mRNA: primary structure and regional quantitation in the brain. DNA Cell Biol. 15:1996;1105-1112
38. Zadina J.E., Hackler L., Ge L.-J., Kastin A.J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature (London). 386:1997;499-502
39. Zhu Y.S., Branch A.D., Robertson H.D., Inturrisi C.E. Cloning and characterization of hamster proenkephalin gene. DNA Cell Biol. 13:1994;25-35
40. 2 opioid receptors. Proc. Natl. Acad. Sci. U.S.A. 85:1988;4061-4065
41. Zurawaski G., Benedik M., Kamb B.J., Abrams J.S., Zurawaski S.M., Lee F.D. Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis. Science. 232:1986;772-775