Bacterial gene profiling assay applied as an alternative method for mode of action classification: Pilot study using chlorinated anilines

Environmental Toxicology and Chemistry

Volumn 30, Issue 5, 2011, Pages 1059-1068

  Dom, Nathalie ^a   Nobels, Ingrid ^a   Knapen, Dries ^a   Blust, Ronny ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Alternative testing; Anilines; Bacterial gene profiling; Biological MOA; Escherichia coli

Indexed keywords

4-CHLOROANILINE; ALTERNATIVE METHODS; ALTERNATIVE TESTING; BACTERIAL GENE PROFILING; BACTERIAL GENES; BIOLOGICAL INFORMATION; BIOLOGICAL MOA; CATEGORIZATION METHODS; CHEMICAL TREATMENTS; DATA SETS; DICHLOROANILINE; ENVIRONMENTAL RISK ASSESSMENT; EXPOSURE CONCENTRATION; GENE EXPRESSION PROFILES; HIGH QUALITY; MEMBRANE DAMAGE; MODE OF ACTION; NON-POLAR; PILOT STUDIES; POLAR NARCOTICS; PROTEIN PERTURBATION; SECOND PHASE; STRUCTURAL ANALOGUE; TOXIC EFFECT;

ANILINE; BACTERIA; BACTERIOLOGY; CHEMICAL ANALYSIS; CHEMICAL COMPOUNDS; ESCHERICHIA COLI; INDICATORS (CHEMICAL); POTASSIUM COMPOUNDS; RISK ASSESSMENT;

GENE EXPRESSION;

2,3,4 TRICHLOROANILINE; 3,5 DICHLOROANILINE; 4 CHLOROANILINE; ANILINE; ANILINE DERIVATIVE; CHLORINE DERIVATIVE; NARCOTIC AGENT; UNCLASSIFIED DRUG;

BACTERIUM; BIOASSAY; CHLORINATED HYDROCARBON; COLIFORM BACTERIUM; CONCENTRATION (COMPOSITION); DATA SET; ENVIRONMENTAL RISK; GENE EXPRESSION; MEMBRANE; OPTIMIZATION; OXIDATION; PROTEIN; RISK ASSESSMENT; TOXICITY;

ARTICLE; ASSAY; BACTERIAL GENE; DRUG MECHANISM; MEMBRANE DAMAGE; NONHUMAN; OXIDATIVE STRESS; PILOT STUDY; PRIORITY JOURNAL; RISK ASSESSMENT;

ANILINE COMPOUNDS; ANIMAL TESTING ALTERNATIVES; CHLORINE COMPOUNDS; ENVIRONMENTAL MONITORING; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION PROFILING; GENES, BACTERIAL; HAZARDOUS SUBSTANCES; OXIDATIVE STRESS; PILOT PROJECTS; RISK ASSESSMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TOXICITY TESTS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 79953747373     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.476     Document Type: Article

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