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3 did not give the product 3a at all.
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3 did not give the product 3a at all.
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3 = 1:1) in toluene gave monobutenylindium along with a small amount of dibutenylindium. The second transmetalation could be relatively fast because the steric hindrance of substituents of 1b (1c) are smaller than those of 1a and 1d.
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56
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79953683618
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note
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The generation of 4d as a single product was observed by NMR spectroscopy.
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The data obtained from the measurement was good, and the analysis was completed to optimize the structure. Although some level A alerts still remain, this structure should be justified because of the excellent level of the data and structure refinement.
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77955137580
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The reaction of 1b with 2 was examined at 0 °C and gave the products in 86% yield and ratio of 3b / 14b = 37/63. This result indicates that the ratio of 3 / 14 does not depend on a reaction temperature.
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3B) or an open air condition is required in a radical initiation step to facilitate an efficient reaction. On the contrary, because nonsubstituted 13e easily generates a radical species (not fully determined) assisted by oxygen, an additional radical initiator is not required.
-
-
-
|