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Volumn 39, Issue 6, 2011, Pages 2378-2392

α-MSH regulates intergenic splicing of MC1R and TUBB3 in human melanocytes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; BETA TUBULIN; BETA TUBULIN 3 PROTEIN; ISOPROTEIN; MELANOCORTIN 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 79953710861     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq1125     Document Type: Article
Times cited : (21)

References (41)
  • 1
    • 33646814991 scopus 로고    scopus 로고
    • Targeting melanocortin receptors as potential novel therapeutics
    • Getting,S.J. (2006) Targeting melanocortin receptors as potential novel therapeutics. Pharmacol. Therapeut., 111, 1-15.
    • (2006) Pharmacol. Therapeut. , vol.111 , pp. 1-15
    • Getting, S.J.1
  • 2
    • 33847188116 scopus 로고    scopus 로고
    • Melanocyte biology and skin pigmentation
    • Lin,J.Y. and Fisher,D.E. (2007) Melanocyte biology and skin pigmentation. Nature, 445, 843.
    • (2007) Nature , vol.445 , pp. 843
    • Lin, J.Y.1    Fisher, D.E.2
  • 5
    • 6344290128 scopus 로고    scopus 로고
    • The genetics of sun sensitivity in humans
    • Rees,J.L. (2004) The genetics of sun sensitivity in humans. Am. J. Hum. Genet., 75, 739-751.
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 739-751
    • Rees, J.L.1
  • 7
    • 0028786945 scopus 로고
    • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
    • Valverde,P., Healy,E., Jackson,I., Rees,J.L. and Thody,A.J. (1995) Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat. Genet., 11, 328-330.
    • (1995) Nat. Genet. , vol.11 , pp. 328-330
    • Valverde, P.1    Healy, E.2    Jackson, I.3    Rees, J.L.4    Thody, A.J.5
  • 10
    • 0026800892 scopus 로고
    • The cloning of a family of genes that encode the melanocortin receptors
    • Mountjoy,K.G., Robbins,L.S., Mortrud,M.T. and Cone,R.D. (1992) The cloning of a family of genes that encode the melanocortin receptors. Science, 257, 1248-1251.
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1    Robbins, L.S.2    Mortrud, M.T.3    Cone, R.D.4
  • 11
    • 33846554676 scopus 로고    scopus 로고
    • Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation
    • April,C.S. and Barsh,G.S. (2007) Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. PLoS Genet., 3, e9.
    • (2007) PLoS Genet. , vol.3
    • April, C.S.1    Barsh, G.S.2
  • 12
    • 10944234560 scopus 로고    scopus 로고
    • Melanocytes and the microphthalmia transcription factor network
    • Steingrimsson,E., Copeland,N.G. and Jenkins,N.A. (2004) Melanocytes and the microphthalmia transcription factor network. Annu. Rev. Genet., 38, 365-411.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 365-411
    • Steingrimsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 14
    • 0028177933 scopus 로고
    • Alpha-melanocyte stimulating hormone and its analogue Nle4DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes
    • Hunt,G., Todd,C., Cresswell,J.E. and Thody,A.J. (1994) Alpha-melanocyte stimulating hormone and its analogue Nle4DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes. J. Cell. Sci., 107(Pt 1), 205-211.
    • (1994) J. Cell. Sci. , vol.107 , Issue.PART 1 , pp. 205-211
    • Hunt, G.1    Todd, C.2    Cresswell, J.E.3    Thody, A.J.4
  • 15
    • 0031242973 scopus 로고    scopus 로고
    • Characterisation of ACTH Peptides in Human Skin and Their Activation of the Melanocortin-1 Receptor
    • Wakamatsu,K., Graham,A., Cook,D. and Thody,A.J. (1997) Characterisation of ACTH peptides in human skin and their activation of the melanocortin-1 receptor. Pigment Cell Res., 10, 288-297. (Pubitemid 127524305)
    • (1997) Pigment Cell Research , vol.10 , Issue.5 , pp. 288-297
    • Wakamatsu, K.1    Graham, A.2    Cook, D.3    Thody, A.J.4
  • 16
    • 33847197910 scopus 로고    scopus 로고
    • Two G-rich regulatory elements located adjacent to and 440 nucleotides downstream of the core poly(A) site of the intronless melanocortin receptor 1 gene are critical for efficient 3′ end processing
    • Dalziel,M., Nunes,N.M. and Furger,A. (2007) Two G-rich regulatory elements located adjacent to and 440 nucleotides downstream of the core poly(A) site of the intronless melanocortin receptor 1 gene are critical for efficient 3′ end processing. Mol. Cell. Biol., 27, 1568-1580.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 1568-1580
    • Dalziel, M.1    Nunes, N.M.2    Furger, A.3
  • 17
    • 77953284100 scopus 로고    scopus 로고
    • Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
    • Millevoi,S. and Vagner,S. (2010) Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation. Nucleic Acids Res., 38, 2757-2774.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 2757-2774
    • Millevoi, S.1    Vagner, S.2
  • 18
    • 2342505693 scopus 로고    scopus 로고
    • New perspectives on connecting messenger RNA 3′ end formation to transcription
    • Proudfoot,N. (2004) New perspectives on connecting messenger RNA 3′ end formation to transcription. Curr. Opin. Cell Biol., 16, 272-278.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 272-278
    • Proudfoot, N.1
  • 19
    • 13744254695 scopus 로고    scopus 로고
    • A large-scale analysis of mRNA polyadenylation of human and mouse genes
    • DOI 10.1093/nar/gki158
    • Tian,B., Hu,J., Zhang,H. and Lutz,C.S. (2005) A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res., 33, 201-212. (Pubitemid 40276942)
    • (2005) Nucleic Acids Research , vol.33 , Issue.1 , pp. 201-212
    • Tian, B.1    Hu, J.2    Zhang, H.3    Lutz, C.S.4
  • 20
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr,C. and Bartel,D.P. (2009) Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell, 138, 673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 21
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • DOI 10.1126/science.1155390
    • Sandberg,R., Neilson,J.R., Sarma,A., Sharp,P.A. and Burge,C.B. (2008) Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science, 320, 1643-1647. (Pubitemid 351931255)
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 23
    • 0024693747 scopus 로고
    • Definition of an efficient synthetic poly(A) site
    • Levitt,N., Briggs,D., Gil,A. and Proudfoot,N.J. (1989) Definition of an efficient synthetic poly(A) site. Genes Dev., 3, 1019-1025.
    • (1989) Genes Dev. , vol.3 , pp. 1019-1025
    • Levitt, N.1    Briggs, D.2    Gil, A.3    Proudfoot, N.J.4
  • 24
    • 77951977370 scopus 로고    scopus 로고
    • A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence
    • Nunes,N.M., Li,W., Tian,B. and Furger,A. (2010) A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence. EMBO J., 29, 1523-1536.
    • (2010) EMBO J. , vol.29 , pp. 1523-1536
    • Nunes, N.M.1    Li, W.2    Tian, B.3    Furger, A.4
  • 25
    • 0032029996 scopus 로고    scopus 로고
    • Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter
    • Greger,I.H., Demarchi,F., Giacca,M. and Proudfoot,N.J. (1998) Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter. Nucleic Acids Res., 26, 1294-1301.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1294-1301
    • Greger, I.H.1    Demarchi, F.2    Giacca, M.3    Proudfoot, N.J.4
  • 27
    • 0034659736 scopus 로고    scopus 로고
    • Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes
    • Busca,R., Abbe,P., Mantoux,F., Aberdam,E., Peyssonnaux,C., Eychene,A., Ortonne,J.-P. and Ballotti,R. (2000) Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes. EMBO J., 19, 2900-2910. (Pubitemid 30386762)
    • (2000) EMBO Journal , vol.19 , Issue.12 , pp. 2900-2910
    • Busca, R.1    Abbe, P.2    Mantoux, F.3    Aberdam, E.4    Peyssonnaux, C.5    Eychene, A.6    Ortonne, J.-P.7    Ballotti, R.8
  • 28
    • 0034617367 scopus 로고    scopus 로고
    • The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells
    • DOI 10.1016/S0014-5793(00)01726-9, PII S0014579300017269
    • Smalley,K. and Eisen,T. (2000) The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells. FEBS Lett., 476, 198-202. (Pubitemid 30410817)
    • (2000) FEBS Letters , vol.476 , Issue.3 , pp. 198-202
    • Smalley, K.1    Eisen, T.2
  • 29
    • 58149144383 scopus 로고    scopus 로고
    • Alternative polyadenylation: A twist on mRNA 3′ end formation
    • Lutz,C.S. (2008) Alternative polyadenylation: a twist on mRNA 3′ end formation. ACS Chem. Biol., 3, 609-617.
    • (2008) ACS Chem. Biol. , vol.3 , pp. 609-617
    • Lutz, C.S.1
  • 32
    • 0346732315 scopus 로고    scopus 로고
    • Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK
    • Poulin,F., Brueschke,A. and Sonenberg,N. (2003) Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. J. Biol. Chem., 278, 52290-52297.
    • (2003) J. Biol. Chem. , vol.278 , pp. 52290-52297
    • Poulin, F.1    Brueschke, A.2    Sonenberg, N.3
  • 33
    • 17144434438 scopus 로고    scopus 로고
    • Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor alpha-chain genes generate a fusion mRNA in normal cells. Implication for the production of multidomain proteins during evolution
    • Magrangeas,F., Pitiot,G., Dubois,S., Bragado-Nilsson,E., Cherel,M., Jobert,S., Lebeau,B., Boisteau,O., Lethe,B., Mallet,J. et al. (1998) Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor alpha-chain genes generate a fusion mRNA in normal cells. Implication for the production of multidomain proteins during evolution. J. Biol. Chem., 273, 16005-16010.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16005-16010
    • Magrangeas, F.1    Pitiot, G.2    Dubois, S.3    Bragado-Nilsson, E.4    Cherel, M.5    Jobert, S.6    Lebeau, B.7    Boisteau, O.8    Lethe, B.9    Mallet, J.10
  • 36
    • 33646540697 scopus 로고    scopus 로고
    • MATN and LAPTM are parts of larger transcription units produced by intergenic splicing: Intergenic splicing may be a common phenomenon
    • Maeda,K., Horikoshi,T., Nakashima,E., Miyamoto,Y., Mabuchi,A. and Ikegawa,S. (2005) MATN and LAPTM are parts of larger transcription units produced by intergenic splicing: intergenic splicing may be a common phenomenon. DNA Res., 12, 365-372.
    • (2005) DNA Res. , vol.12 , pp. 365-372
    • Maeda, K.1    Horikoshi, T.2    Nakashima, E.3    Miyamoto, Y.4    Mabuchi, A.5    Ikegawa, S.6
  • 37
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
    • Lasa,M., Mahtani,K.R., Finch,A., Brewer,G., Saklatvala,J. and Clark,A.R. (2000) Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol. Cell. Biol., 20, 4265-4274.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 38
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • DOI 10.1093/emboj/18.18.4969
    • Winzen,R., Kracht,M., Ritter,B., Wilhelm,A., Chen,C.Y., Shyu,A.B., Muller,M., Gaestel,M., Resch,K. and Holtmann,H. (1999) The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J., 18, 4969-4980. (Pubitemid 29443799)
    • (1999) EMBO Journal , vol.18 , Issue.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.-Y.A.5    Shyu, A.-B.6    Muller, M.7    Gaestel, M.8    Resch, K.9    Holtmann, H.10
  • 39
    • 15444365234 scopus 로고    scopus 로고
    • Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse Melanocortin 1 receptors
    • Sanchez-Mas,J., Guillo,L.A., Zanna,P., Jimenez-Cervantes,C. and Garcia-Borron,J.C. (2005) Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse Melanocortin 1 receptors. Mol. Endocrinol., 19, 1035-1048.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1035-1048
    • Sanchez-Mas, J.1    Guillo, L.A.2    Zanna, P.3    Jimenez-Cervantes, C.4    Garcia-Borron, J.C.5
  • 41
    • 0037764082 scopus 로고    scopus 로고
    • Class III beta-tubulin in human development and cancer
    • DOI 10.1002/cm.10116
    • Katsetos,C.D., Herman,M.M. and Mork,S.J. (2003) Class III beta-tubulin in human development and cancer. Cell Motil Cytoskeleton, 55, 77-96. (Pubitemid 36627260)
    • (2003) Cell Motility and the Cytoskeleton , vol.55 , Issue.2 , pp. 77-96
    • Katsetos, C.D.1    Herman, M.M.2    Mork, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.