Binding of [123I]iodobenzamide to the rat D2 receptor after challenge with various doses of methylphenidate: An in vivo imaging study with dedicated small animal SPECT

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 38, Issue 4, 2011, Pages 694-701

  Nikolaus, Susanne ^c   Antke, Christina ^c   Beu, Markus ^c   Kley, Konstantin ^a   Wirrwar, Andreas ^c   Huston, Joseph P ^b   Müller, Hans Wilhelm ^c  

^a Institute of Radiology and Nuclear Medicine   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

123I Iodobenzamide; ADHD; D2 receptor; Methylphenidate; Small animal SPECT

Indexed keywords

2,3 DICARBOXYPROPANE 1,1 DIPHOSPHONATE TECHNETIUM TC 99M; DOPAMINE 2 RECEPTOR; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; IODINE 123; IODOBENZAMIDE I 123; METHYLPHENIDATE; RACLOPRIDE C 11; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M; TETROFOSMIN TC 99M; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; DOPAMINE; IDOBENZAMIDE; IODOBENZENE;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; IMAGING; MALE; NONHUMAN; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ANIMAL; DRUG EFFECT; METABOLISM; NEOSTRIATUM; PROTEIN BINDING; WISTAR RAT;

ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; IODOBENZENES; MALE; METHYLPHENIDATE; NEOSTRIATUM; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 79953682513     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-010-1668-x     Document Type: Article

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