2′-Hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma

Carcinogenesis

Volumn 32, Issue 4, 2011, Pages 568-575

  Nagaprashantha, Lokesh Dalasanur ^a   Vatsyayan, Rit ^a   Singhal, Jyotsana ^a   Lelsani, Poorna ^a   Prokai, Laszlo ^a   Awasthi, Sanjay ^a   Singhal, Sharad S ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' HYDROXYFLAVANONE; CD31 ANTIGEN; CYCLIN B1; CYCLIN DEPENDENT KINASE 4; EPIDERMAL GROWTH FACTOR RECEPTOR; FLAVANONE DERIVATIVE; GLUTATHIONE TRANSFERASE P1; KI 67 ANTIGEN; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN; 2'-HYDROXYFLAVANONE; 3 ALPHA BETA, 20 BETA HYDROXYSTEROID DEHYDROGENASE; 3 ALPHA-BETA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE; 3ALPHA(OR 20BETA) HYDROXYSTEROID DEHYDROGENASE; GSTP1 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; VHL PROTEIN, HUMAN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CITRUS FRUIT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENE EXPRESSION; GENE MUTATION; GENETIC RISK; KIDNEY CARCINOMA; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; ORANGE (FRUIT); PHENOTYPE; PRIORITY JOURNAL; RISK REDUCTION; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; ANIMAL; CELL CYCLE; CELL MOTION; DRUG EFFECT; DRUG SCREENING; GENETICS; HUMAN; KIDNEY TUMOR; MUTATION; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; VASCULARIZATION;

20-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CARCINOMA, RENAL CELL; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FLAVANONES; GLUTATHIONE S-TRANSFERASE PI; HUMANS; KIDNEY NEOPLASMS; MICE; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79953682228     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr021     Document Type: Article

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