Gastroprotective effects of stachys lavandulifolia extract on experimental gastric ulcer

African Journal of Pharmacy and Pharmacology

Volumn 5, Issue 2, 2011, Pages 155-159

  Nabavizadeh, Fatemeh ^a   Alizadeh, Ali Mohammad ^a   Adeli, Soheila ^a   Golestan, Masoumeh ^a   Moloudian, Hamid ^a   Kamalinejad, Mohammad ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acid; Nitric oxide; Pepsin; Stachys lavandulifolia

Indexed keywords

ALCOHOL; NITRIC OXIDE; PEPSIN A; PLANT EXTRACT; STACHYS LAVANDULIFOLIA EXTRACT; STOMACH SECRETION INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; MALE; NONHUMAN; PEPSIN SECRETION; RAT; STACHYS; STACHYS LAVANDULIFOLIA; STOMACH ACID SECRETION; STOMACH PROTECTION; STOMACH ULCER;

EID: 79953665992     PISSN: None     EISSN: 19960816     Source Type: Journal    
DOI: 10.5897/AJPP10.296     Document Type: Article

References (35)

1. Basil MD, Howard MS (1995). Clinical Gastroenterology. 4th Ed. New York: Mc-Graw- Hill. pp. 113-161.
2. Bersted A (1970). A modified hemoglobin substrate method for the estimation of pepsin in gastric juice. Scan. J. Gastroenterol., 5(5): 347-348.
3. Delazar A, Celik S, Gokturk RS, Unal O, Nahar L, Sarker SD (2005). Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity. Pharmazie, 60(11): 878-880.
4. Dijkstra G, Van Goor H, Jansen PL, Moshage H (2004). Targeting nitric oxide in the gastrointestinal tract. Curr. Opin. Investig. Drugs, 5(5): 529-536.
5. Evans WC (2002). Trease and Evans Pharmacognosy. 15th Ed, London: Sounders W.B. pp. 214-327.
6. Ghasemi-Pirbalouti A (2011). Wound Healing Activity of Extracts of Malva sylvestris and Stachys lavandulifolia. Int. J. Bio., 3(1): 174-179.
7. Hajhashemi V, Ghannadi A, Sedighifar S (2007). Analgesic and antiinflammatory properties of the hydroalcoholic, polyphenolic and boiled extracts of Stachys lavandulifolia. R.P.S., 2: 92-98.
8. Herring N, Danson EJ, Paterson DJ (2002). Cholinergic control of heart rate by nitric oxide is site specific. News. Physiol. Sci., 17: 202-206.
9. Herring N, Paterson DJ (2001). Nitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitro. J. Physiol., 535(2): 507-518.
10. Hollander D, Taranawski A, Krause WJ, Gergely H (1985). Protective effect of sucralfate against alcohol-induced gastric mucosal inury in the rat. Gastroenterol., 88(1): 366-374.
11. Javidnia K, Mojab F, Mojahedi SA (2004). Chemical constituents ofessential oil of Stachys lavandulifolia Vahl from Iran. Iranian. J. Pharm. Res., 3: 61-63.
12. Karioti A, Bolognesi L, Vincieri FF, Bilia AR (2010). Analysis of the constituents of aqueous preparations of Stachys recta by HPLC-DAD and HPLC-ESI-MS. J. Pharm. Biomed. Anal., 53(1): 15-23.
13. Kato S, Kitamura M, Korolkiewicz RP, Takeuchi K (1998). Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitor. Br. J. Pharmacol., 123(5): 839-846.
14. Khanavi M, Sharifzadeh M, Hadjiakhoondi A, Shafiee A (2005). Phytochemical investigation and anti-inflammatory activity of aerial parts of Stachys byzanthina C. Koch. J. Ethnopharmacol., 21; 97(3): 463-468.
15. Kim H, Kim KH (1998). Effect of nitric oxide on hydrogen peroxideinduced damage in isolated rabbit gastric glands. Pharmacology, 57(6): 323-330.
16. Kushima H, Hiruma-Lima CA, Santos MA, Viana E, Coelho-Ferreira M, Brito AR (2005). Gastroprotective activity of Pradosia huberi on experimentally induced gastric lesions in rodents: role of endogenous sulphydryls and nitric oxide. J. Ethnopharmacol., 3; 101(1-3): 61-67.
17. Maleki N, Garjani A, Nazemiyeh H, Nilfouroushan N, Eftekhar Sadat AT, Allameh Z, Hasannia N (2001). Potent anti-inflammatory activities of hydroalcoholic extract from aerial parts of Stachys inflata on rats. J. Ethnopharmacol., 75(2-3): 213-218.
18. Nabavizadeh RF, Vahedian J (2004). The effect of insulin-dependent diabetes mellitus on basal and distention-induced acid and pepsin secretion in rat. Diabetes. Res. Clin. Pract., 66(1): 1-6.
19. Nabavizadeh F, Salimi E, Sadroleslami Z, Vahedian J (2009). Saffron (Crocus sativus) increases gastric acid and pepsin secretions in rats: Role of nitric oxide. Afr. J. Pharm. Pharmacol., 3(5): 181-184.
20. Naghibi F, Mosaddegh M, Motamed SM, Ghorbani A (2005). Labiatae Family in Folk Medicine in Iran: from Ethnobotany to Pharmacology. I.J.P.R. 4(2): 63-79.
21. Nahrevanian H, Gholizadeh J, Farahmand M, Assmar M, Sharifi K, Ayatollahi Mousavi SA, Abolhassani M (2006). Nitric oxide induction as a novel immune-epidemiological target in malaria-infected patients from endemic areas of the Islamic Republic of Iran. Scand. J. Clin. Lab. Invest., 66(3): 201-209.
22. Nash J, Lambert L, Deakin M (1994). Histamine H2-receptor antagonists in peptic ulcer disease. Evidence for a prophylactic use. Drugs. 47(6): 862-871.
23. Ozdil S, Yanardag R, Koyuturk M, bolkent S, Arbak S (2004). Protective effects of ascorbic acid, DL-_-Tocopherol acetate, and sodium selenate on ethanol-induced gastric mucosal injury of rats. Bio. Trace. Elem. Res., 99(1-3): 173-189.
24. Premkumar K, Abraham SK, Santhiya ST, Ramesh A (2003). Protective effects of saffron (Crocus sativus Linn.) on genotoxins-induced oxidative stress in Swiss albino mice. Phytother. Res., 17(6): 614-617
25. Salim AS (1988). Gastric diversion: a method for H+ output estimation in the rat. Digestion. 39(1): 47-51.
26. Singha S, Khajuriaa A, Tanejab SC, Khajuriab RK, Singha S, Qazia GN (2008). The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats. Phytomedicine, 15(6-7): 408-415.
27. Skaltsa HD, Demetzos C, Lazari D, Sokovic M (2003). Essential oil analysis and antimicrobial activity of eight Stachys species from Greece. Phytochemistry. 64(3): 743-752.
28. Skaltsa HD, Lazari DM, Chinou IB, Loukis AE (1999). Composition and antibacterial activity of the essential oils of Stachys candida and S. chrysantha from southern Greece. Planta. Med., 65(3): 255-256.
29. Souza MHL, Paula Lemos H, Oliveira RB, Cunha FQ (2004). Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide (iNOS) synthase deficient mice. Gut., 53(6): 791-796.
30. Tanaka A, Mizoguchi H, Kunikata T, Miyazawa T, Takeuchi K (2001). Protection by constitutively formed nitric oxide of intestinal damage induced by indomethacin in rats. J. Physiol. Paris., 95(1-6): 35-41.
31. Tepperman BL, Whittle BJ (1992). Endogenous nitric oxide and sensory neuropeptides interact in the modulation of the rat gastric microcirculation. Br. J. Pharmacol., 105(1): 171-175.
32. Tripp MA, Tepperman BL (1995). Effect of nitric oxide on integrity, blood flow and cyclic GMP levels in the rat gastric mucosa: modulation by sialoadenectomy. Br. J. Pharmacol., 115(2): 344-348.
33. Vogel HG, Vogel WH (1997). Drug discovery and evaluation (Pharmacological assays). Berlin: Springer Verlag Co. 2; 486-487.
34. Wallace JL, Granger DN (1996). The cellular and molecular basis of gastric mucosal defense. FASEB. J., 10(7): 731-740.
35. Whittle BJ, Lopez-Belmonte J, Moncada S (1990). Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat. Br. J. Pharmacol., 99(3): 607-611.